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公开(公告)号:US12053379B2
公开(公告)日:2024-08-06
申请号:US17181722
申请日:2021-02-22
申请人: CARDIOVALVE LTD.
发明人: Ilia Hariton , Boaz Harari , Maxim Karalnik , Michael Albitov , Meni Iamberger
CPC分类号: A61F2/2436 , A61F2/2433 , A61F2/966 , A61F2002/9583
摘要: A delivery tool includes a nosepiece that is fixed to a shaft, and distal to an implant, and an expandable element proximal to the nosepiece. Maximally-expanded, the expandable element (i) has an expanded external diameter at its widest part that is smaller than the expanded internal diameter of a lumen of the frame of the implant, (ii) tapers proximally away from the widest part and from the nosepiece, and (iii) is dimensioned to slide proximally through the lumen of the implant in its expanded state, between leaflets of the implant, and out of the lumen. When non-expanded, the widest part of the expandable element has a non-expanded external diameter that is smaller than the expanded external diameter of the expandable element. In a compressed state of the implant a portion of the expandable element is disposed within the lumen of the frame. Other applications are also described.
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公开(公告)号:US20240216128A1
公开(公告)日:2024-07-04
申请号:US18601399
申请日:2024-03-11
申请人: CARDIOVALVE LTD.
发明人: Yossi GROSS , Gil HACOHEN , Eran MILLER , Yuval ZIPORY , Tal REICH , Meir KUTZIK , Rotem NEEMAN
IPC分类号: A61F2/24 , A61B17/00 , A61B17/122 , A61F2/848
CPC分类号: A61F2/2418 , A61B17/122 , A61F2/2409 , A61F2/2436 , A61F2/2439 , A61F2/2454 , A61F2/246 , A61F2/2466 , A61B2017/00243 , A61F2/2427 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2463 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0091 , A61F2230/0006 , A61F2230/0013 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0015 , A61F2250/006 , A61F2250/0069 , A61F2250/0071
摘要: For some applications, apparatus is provided for facilitating implantation of a prosthetic valve (150) at a native heart valve (120) of a subject, the apparatus comprising a prosthetic valve support (22), the prosthetic valve support (a) being configured to be transluminally-deliverable to the native valve and to be deployable at the native valve, and (b) comprising one or more tissue-engaging elements (24), configured to couple the prosthetic valve support to leaflets (128) of the native valve without eliminating check valve functionality of the native valve. Other embodiments are also described.
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公开(公告)号:US12023243B2
公开(公告)日:2024-07-02
申请号:US17010886
申请日:2020-09-03
申请人: CARDIOVALVE LTD.
发明人: Ilia Hariton , Meni Iamberger , Aviram Baum , Boaz Harari
IPC分类号: A61F2/24
CPC分类号: A61F2/2427 , A61F2/243 , A61F2/2436 , A61F2/2445 , A61F2/2454 , A61F2/2463 , A61F2/2409 , A61F2/2418 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/007
摘要: A prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an annular valve body. The prosthetic valve may also include a plurality of tissue anchors arranged about the valve body and configured to extend from connection points on the valve body. The prosthetic valve may also include at least one protective fabric covering extending over each of the connection points between each tissue anchor and the valve body.
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公开(公告)号:US11937795B2
公开(公告)日:2024-03-26
申请号:US17683875
申请日:2022-03-01
申请人: CARDIOVALVE LTD.
发明人: Ilia Hariton , Tal Reich , Paul Kaye
CPC分类号: A61B17/0057 , A61F2/2427 , A61M27/002 , A61B2017/00247 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61F2/2412 , A61F2/2436 , A61F2002/249 , A61F2210/0057 , A61M2210/125
摘要: During a medical procedure, a transseptal fenestration is made at a septum of the heart and a shunt is implanted into the transseptal fenestration. During the same medical procedure, a transapical puncture is made into a left ventricle of the heart. A prosthetic valve is delivered via the transapical puncture and implanted at a mitral valve of the heart. Subsequently to delivering the prosthetic valve and making the transseptal fenestration, the transapical puncture is closed. Other embodiments are also described.
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公开(公告)号:US11793638B2
公开(公告)日:2023-10-24
申请号:US16896858
申请日:2020-06-09
申请人: CARDIOVALVE LTD.
发明人: Ilia Hariton , Boaz Harari
CPC分类号: A61F2/2436 , A61F2/243 , A61F2/2409 , A61F2/2418 , A61F2/9517 , A61F2002/91575 , A61F2220/0016 , A61F2220/0025
摘要: Prosthetic heart valves and methods of use of prosthetic heart valves may be provided. In one implementation, a prosthetic heart valve may include an annular valve body and atrial anchors and ventricular anchors extending from the valve body. An atrial anchor may include a pivoting portion configured to extend in an upstream direction when the prosthetic heart valve is in a delivery configuration and in a downstream direction when the prosthetic heart valve is in a deployed-anchor configuration. A portion of a ventricular anchor may be configured to abut the annular valve body when the prosthetic heart valve is arranged in the delivery configuration.
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公开(公告)号:US11793635B2
公开(公告)日:2023-10-24
申请号:US17004693
申请日:2020-08-27
申请人: CARDIOVALVE LTD.
发明人: Ilia Hariton , Boaz Harari
CPC分类号: A61F2/2436 , A61F2/243 , A61F2/2409 , A61F2/2418 , A61F2/9517 , A61F2002/91575 , A61F2220/0016 , A61F2220/0025
摘要: Prosthetic valves and methods of use of prosthetic valves may be provided. In one implementation, a prosthetic valve may include an annular outer frame formed of struts intersecting at outer frame junctions, an inner frame situated within the outer frame and formed of struts intersecting at inner frame junctions, and a plurality of tissue anchors extending from the outer frame. The junctions along a downstream end of the outer frame may be spaced apart circumferentially from the junctions along a downstream end of the inner frame. The outer frame may include an anchor support strut extending between a downstream junction of the outer frame and a point of connection between one of the tissue anchors and the outer frame. The anchor support strut may be configured for placement parallel to a longitudinal axis of the prosthetic valve.
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公开(公告)号:US20230293293A1
公开(公告)日:2023-09-21
申请号:US18125350
申请日:2023-03-23
申请人: CARDIOVALVE LTD.
发明人: Maxim KARALNIK , Michael ALBITOV , Oren SHUA , Meni IAMBERGER , Ilia HARITON
CPC分类号: A61F2/2415 , A61F2/2427 , B21D39/048 , A61F2/9522 , A61F2/9525 , Y10T29/49865 , A61F2210/0014
摘要: An assembly (10) for crimping a frame (56) of an implant (58) comprises a crimping device (20) with a base (22) and a crimping mechanism (24) that defines a crimping aperture (26). A bath (28) having a floor (30), and one or more side-walls (32) extending upward from the floor to a side-wall height defines a receptacle (18) that is shaped to receive a portion of the crimping device. The apparatus has an assembled state in which the portion of the crimping device has been received by the receptacle, the crimping device is held securely by the bath, and the aperture is below the side-wall height. Other embodiments are also described.
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公开(公告)号:US20230248352A1
公开(公告)日:2023-08-10
申请号:US18136504
申请日:2023-04-19
申请人: CARDIOVALVE LTD.
发明人: Yossi GROSS , Gil HACOHEN , Eran MILLER , Yuval ZIPORY , Tal REICH
CPC分类号: A61B17/0401 , A61F2/2409 , A61F2/2418 , A61F2/2436 , A61F2/2457 , A61F2/2466 , A61F2/2427 , A61F2/243 , A61F2/2412 , A61F2220/0016 , A61F2230/0041 , A61F2230/005 , A61B2017/00243
摘要: Apparatus and methods are described including a prosthetic valve support (40) configured to be placed at a patient's native atrioventricular valve annulus. The valve support defines an annular element (44) that defines an inner cross-sectional area thereof. An expandable prosthetic valve (80) is placed into the patient's ventricle, the prosthetic valve including an expandable frame (79) and prosthetic valve leaflets (82) coupled to the frame. When the frame is in a non-constrained state thereof, a cross-sectional area of the frame, along at least a given portion L of the frame's length, is greater than the cross-sectional area defined by the annular element. The prosthetic valve is couplable to the prosthetic valve support at any location along the portion, by the frame being expanded when the location along the portion is aligned with the annular element. Other applications are also described.
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公开(公告)号:US11701225B2
公开(公告)日:2023-07-18
申请号:US16746489
申请日:2020-01-17
申请人: CARDIOVALVE LTD.
发明人: Tal Hammer , Meni Iamberger , Yuval Zipory , Michael Albitov , Tal Reich , Ilia Hariton
CPC分类号: A61F2/2436 , A61F2/2418 , A61F2/2439 , A61F2002/828 , A61F2220/0025 , A61F2230/001 , A61F2230/0067 , A61F2250/0039
摘要: Apparatus includes a delivery tool and a prosthetic valve, the prosthetic valve includes a first frame, and a second frame coupled to the first frame. The delivery tool includes a first catheter, a second catheter, and a rod. A steerable portion of the second catheter extends out of the first catheter, and a steerable distal portion of the rod extends out of the second catheter. An extracorporeal rod-controller is operably coupled to the rod such that operating the extracorporeal rod-controller steers the steerable distal portion of the rod. In a delivery state of the apparatus, the prosthetic valve is compressed onto the rod, distal to the distal end of the second catheter, and the apparatus is transfemorally and transseptally advanceable into a left atrium of a heart of a subject. Other embodiments are also described.
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公开(公告)号:US20230218399A1
公开(公告)日:2023-07-13
申请号:US17956319
申请日:2022-09-29
申请人: CARDIOVALVE LTD.
发明人: Yonatan KISLEV , Or COHEN , Meni IAMBERGER
IPC分类号: A61F2/24
CPC分类号: A61F2/2472 , A61F2/2415
摘要: A method for grouping prosthetic valve leaflets of an aggregate of prosthetic valve leaflets is provided. Using a computer processor, for each leaflet of the aggregate, in response to an image parameter of the leaflet, a leaflet-flexibility value is derived. A group size value is provided to the processor. Using the processor, at least some of the leaflets of the aggregate are designated into leaflet groups, based on similarity between the respective leaflet-flexibility value of each leaflet of the aggregate. Each of the leaflet groups includes a number of leaflets equal to the group size value. Using the processor, an indication of the designated leaflet groups is outputted. Other embodiments are also described.
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