Minimally-invasive delivery systems

    公开(公告)号:US12053379B2

    公开(公告)日:2024-08-06

    申请号:US17181722

    申请日:2021-02-22

    申请人: CARDIOVALVE LTD.

    IPC分类号: A61F2/24 A61F2/966 A61F2/958

    摘要: A delivery tool includes a nosepiece that is fixed to a shaft, and distal to an implant, and an expandable element proximal to the nosepiece. Maximally-expanded, the expandable element (i) has an expanded external diameter at its widest part that is smaller than the expanded internal diameter of a lumen of the frame of the implant, (ii) tapers proximally away from the widest part and from the nosepiece, and (iii) is dimensioned to slide proximally through the lumen of the implant in its expanded state, between leaflets of the implant, and out of the lumen. When non-expanded, the widest part of the expandable element has a non-expanded external diameter that is smaller than the expanded external diameter of the expandable element. In a compressed state of the implant a portion of the expandable element is disposed within the lumen of the frame. Other applications are also described.

    Prosthetic valve with angularly offset frames

    公开(公告)号:US11793635B2

    公开(公告)日:2023-10-24

    申请号:US17004693

    申请日:2020-08-27

    申请人: CARDIOVALVE LTD.

    IPC分类号: A61F2/24 A61F2/95 A61F2/915

    摘要: Prosthetic valves and methods of use of prosthetic valves may be provided. In one implementation, a prosthetic valve may include an annular outer frame formed of struts intersecting at outer frame junctions, an inner frame situated within the outer frame and formed of struts intersecting at inner frame junctions, and a plurality of tissue anchors extending from the outer frame. The junctions along a downstream end of the outer frame may be spaced apart circumferentially from the junctions along a downstream end of the inner frame. The outer frame may include an anchor support strut extending between a downstream junction of the outer frame and a point of connection between one of the tissue anchors and the outer frame. The anchor support strut may be configured for placement parallel to a longitudinal axis of the prosthetic valve.

    Delivery of a prosthetic valve
    9.
    发明授权

    公开(公告)号:US11701225B2

    公开(公告)日:2023-07-18

    申请号:US16746489

    申请日:2020-01-17

    申请人: CARDIOVALVE LTD.

    IPC分类号: A61F2/24 A61F2/82

    摘要: Apparatus includes a delivery tool and a prosthetic valve, the prosthetic valve includes a first frame, and a second frame coupled to the first frame. The delivery tool includes a first catheter, a second catheter, and a rod. A steerable portion of the second catheter extends out of the first catheter, and a steerable distal portion of the rod extends out of the second catheter. An extracorporeal rod-controller is operably coupled to the rod such that operating the extracorporeal rod-controller steers the steerable distal portion of the rod. In a delivery state of the apparatus, the prosthetic valve is compressed onto the rod, distal to the distal end of the second catheter, and the apparatus is transfemorally and transseptally advanceable into a left atrium of a heart of a subject. Other embodiments are also described.

    LEAFLET-GROUPING SYSTEM
    10.
    发明公开

    公开(公告)号:US20230218399A1

    公开(公告)日:2023-07-13

    申请号:US17956319

    申请日:2022-09-29

    申请人: CARDIOVALVE LTD.

    IPC分类号: A61F2/24

    CPC分类号: A61F2/2472 A61F2/2415

    摘要: A method for grouping prosthetic valve leaflets of an aggregate of prosthetic valve leaflets is provided. Using a computer processor, for each leaflet of the aggregate, in response to an image parameter of the leaflet, a leaflet-flexibility value is derived. A group size value is provided to the processor. Using the processor, at least some of the leaflets of the aggregate are designated into leaflet groups, based on similarity between the respective leaflet-flexibility value of each leaflet of the aggregate. Each of the leaflet groups includes a number of leaflets equal to the group size value. Using the processor, an indication of the designated leaflet groups is outputted. Other embodiments are also described.