TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS
    1.
    发明申请
    TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS 有权
    治疗真菌和/或功能性感染

    公开(公告)号:US20120258907A1

    公开(公告)日:2012-10-11

    申请号:US13335549

    申请日:2011-12-22

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    摘要: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.

    摘要翻译: 本发明涉及多肽的用途,其包含衍生自载脂蛋白的硫酸肝素蛋白多糖(HSPG)受体结合区域的肽的重复物,用于治疗或预防真菌和/或原生生物感染。 本发明还涉及这种肽用于治疗或预防用这些肽污染表面或物体的用途。

    Treatment of fungal and/or protist infections
    2.
    发明授权
    Treatment of fungal and/or protist infections 有权
    治疗真菌和/或原生生殖感染

    公开(公告)号:US08916516B2

    公开(公告)日:2014-12-23

    申请号:US13335549

    申请日:2011-12-22

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    摘要: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.

    摘要翻译: 本发明涉及多肽的用途,其包含衍生自载脂蛋白的硫酸肝素蛋白多糖(HSPG)受体结合区域的肽的重复物,用于治疗或预防真菌和/或原生生物感染。 本发明还涉及这种肽用于治疗或预防用这些肽污染表面或物体的用途。

    Treatment of bacterial infections

    公开(公告)号:US08524861B2

    公开(公告)日:2013-09-03

    申请号:US10586416

    申请日:2005-02-28

    IPC分类号: C07K7/08

    摘要: The invention relates to polypeptides, comprising repeats of peptides derived from apolipoproteins, which exhibit antibacterial activity and to nucleic acids encoding the same. The invention further provides the use of such polypeptides, derivatives, analogues or nucleic acids as medicaments, and also their use in methods of preventing or treating bacterial infection or objects and surfaces. The invention further extends to objects, such as contact lenses, coated with the polypeptides.

    TREATMENT OF VIRAL INFECTIONS
    4.
    发明申请
    TREATMENT OF VIRAL INFECTIONS 审中-公开
    治疗病毒感染

    公开(公告)号:US20100221273A1

    公开(公告)日:2010-09-02

    申请号:US12702919

    申请日:2010-02-09

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    CPC分类号: C07K7/08 A61K38/00 C07K14/775

    摘要: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.

    摘要翻译: 本发明涉及来自apoE141-149的串联重复的多肽及其作为药物的用途。 肽可以包含串联重复序列及其截短,其中至少一个亮氨酸(L)被具有至少4个碳原子和至少一个氮原子的侧链的氨基酸替代。 这样的肽可用于预防或治疗病毒感染。

    Treatment of viral infections
    5.
    发明授权
    Treatment of viral infections 有权
    病毒感染的治疗

    公开(公告)号:US08017579B2

    公开(公告)日:2011-09-13

    申请号:US10580984

    申请日:2004-12-20

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    IPC分类号: C07K7/08 A61K38/10

    CPC分类号: C07K14/775 A61K38/00

    摘要: The present invention relates to polypeptides, and derivatives or analogues thereof, comprising a tandem repeat of apolipoprotein B, or a truncation thereof, derived from an HSPG receptor binding region of apolipoprotein B. Such peptides are useful for treating or preventing the development of viral infections.

    摘要翻译: 本发明涉及多肽及其衍生物或类似物,其包含衍生自载脂蛋白B的HSPG受体结合区的载脂蛋白B的串联重复序列或其截短。这些肽可用于治疗或预防病毒感染的发展 。

    Antiviral polypeptides comprising tandem repeats of APOE 141-149 and variants thereof
    6.
    发明授权
    Antiviral polypeptides comprising tandem repeats of APOE 141-149 and variants thereof 有权
    包含APOE 141-149的串联重复的抗病毒多肽及其变体

    公开(公告)号:US07691382B2

    公开(公告)日:2010-04-06

    申请号:US10580761

    申请日:2004-12-17

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    IPC分类号: A61K39/00

    CPC分类号: C07K7/08 A61K38/00 C07K14/775

    摘要: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.

    摘要翻译: 本发明涉及来自apoE141-149的串联重复的多肽及其作为药物的用途。 肽可以包含串联重复序列及其截短,其中至少一个亮氨酸(L)被具有至少4个碳原子和至少一个氮原子的侧链的氨基酸替代。 这样的肽可用于预防或治疗病毒感染。

    TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS
    7.
    发明申请
    TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS 审中-公开
    治疗真菌和/或功能性感染

    公开(公告)号:US20150190462A1

    公开(公告)日:2015-07-09

    申请号:US14542319

    申请日:2014-11-14

    申请人: Ai2 Limited

    发明人: Curtis Dobson

    IPC分类号: A61K38/16 A01N37/30 A61K38/10

    摘要: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.

    摘要翻译: 本发明涉及多肽的用途,其包含衍生自载脂蛋白的硫酸肝素蛋白多糖(HSPG)受体结合区域的肽的重复物,用于治疗或预防真菌和/或原生生物感染。 本发明还涉及这种肽用于治疗或预防用这些肽污染表面或物体的用途。

    TREATMENT OF VIRAL INFECTIONS
    8.
    发明申请
    TREATMENT OF VIRAL INFECTIONS 审中-公开
    治疗病毒感染

    公开(公告)号:US20130150288A1

    公开(公告)日:2013-06-13

    申请号:US13550029

    申请日:2012-07-16

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    IPC分类号: C07K7/08

    CPC分类号: C07K7/08 A61K38/00 C07K14/775

    摘要: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.

    摘要翻译: 本发明涉及来自apoE141-149的串联重复的多肽及其作为药物的用途。 肽可以包含串联重复序列及其截短,其中至少一个亮氨酸(L)被具有至少4个碳原子和至少一个氮原子的侧链的氨基酸替代。 这样的肽可用于预防或治疗病毒感染。

    Treatment of Fungal and/or Protist Infections
    9.
    发明申请
    Treatment of Fungal and/or Protist Infections 审中-公开
    真菌和/或原始感染的治疗

    公开(公告)号:US20080207508A1

    公开(公告)日:2008-08-28

    申请号:US11916627

    申请日:2006-06-26

    申请人: Curtis Dobson

    发明人: Curtis Dobson

    IPC分类号: A61K38/00

    摘要: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.

    摘要翻译: 本发明涉及多肽的用途,其包含衍生自载脂蛋白的硫酸肝素蛋白多糖(HSPG)受体结合区域的肽的重复物,用于治疗或预防真菌和/或原生生物感染。 本发明还涉及这种肽用于治疗或预防用这些肽污染表面或物体的用途。