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公开(公告)号：US20030054405A1
公开(公告)日：2003-03-20
申请号：US09999833
申请日：2001-10-24
Applicant: Genentech, Inc.
Inventor： Avi Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C07K014/435 , A61K031/17 , C12P021/02 , C12N005/06
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20030050240A1
公开(公告)日：2003-03-13
申请号：US09978403
申请日：2001-10-16
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William l. Wood
IPC: A61K038/17 , G01N033/53 , C07H021/04 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: G11B5/022 , C07K2317/24 , C07K2319/30 , H04B10/508
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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Patent Agency Ranking
公开(公告)号：US20030050239A1
公开(公告)日：2003-03-13
申请号：US09978191
申请日：2001-10-15
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20030045462A1
公开(公告)日：2003-03-06
申请号：US09978608
申请日：2001-10-16
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20030004102A1
公开(公告)日：2003-01-02
申请号：US09978189
申请日：2001-10-15
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K038/17 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20020192209A1
公开(公告)日：2002-12-19
申请号：US10001054
申请日：2001-11-30
Applicant: GENENTECH, INC.
Inventor： Kevin P. Baker , Audrey Goddard , Austin L. Gurney , Caroline Hebert , William Henzel , Rhona C. Kabakoff , David L. Shelton , Victoria Smith , Colin K. Watanabe , William I. Wood
IPC: A61K039/395 , C07H021/04 , C12N009/00 , C07K016/30 , C12P021/02 , C12N005/06
Abstract: The present invention concerns methods and compositions for inhibiting neoplastic cell growth. In particular, the present invention concerns antitumor compositions and methods for the treatment of tumors. The invention further concerns screening methods for identifying growth inhibitory, e.g., antitumor compounds. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及用于抑制肿瘤细胞生长的方法和组合物。 特别地，本发明涉及用于治疗肿瘤的抗肿瘤组合物和方法。 本发明还涉及用于鉴定生长抑制性例如抗肿瘤化合物的筛选方法。 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US20020177553A1
公开(公告)日：2002-11-28
申请号：US09978192
申请日：2001-10-15
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K038/17 , C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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