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    SYSTEM AND APPARATUS FOR INCREASING REGULARITY AND/OR PHASE-LOCKING OF NEURAL ACTIVITY RELATING TO AN EPILEPTIC EVENT
    85.
    发明申请
    SYSTEM AND APPARATUS FOR INCREASING REGULARITY AND/OR PHASE-LOCKING OF NEURAL ACTIVITY RELATING TO AN EPILEPTIC EVENT 有权
    增加与临床活动相关的神经活动的正常和/或相位锁定的系统和装置

    公开(公告)号：US20150174407A1

    公开(公告)日：2015-06-25

    申请号：US14638890

    申请日：2015-03-04

    Applicant: Flint Hills Scientific, L.L.C.

    Inventor： Ivan Osorio

    IPC: A61N1/36

    CPC classification number: A61N1/36064 ,  A61N1/0529 ,  A61N1/36114 ,  A61N1/36139 ,  A61N1/36142 ,  A61N1/36171

    Abstract: A method, comprising detecting, in at least a first brain region of a patient, an electrical activity relating to an epileptic activity; determining a first regularity index of said electrical activity; and applying at least one first electrical stimulation to at least one neural target of said patient for treating said epileptic event, in response to said first regularity index being within a first range. A non-transitive, computer-readable storage device for storing instructions that, when executed by a processor, perform the method. A medical device system suitable for use in the method.

    Abstract translation: 一种方法，包括在患者的至少第一脑区域中检测与癫痫活动相关的电活动; 确定所述电活动的第一规律指数; 以及响应于所述第一规律性指数在第一范围内，将至少一个第一电刺激应用于所述患者的至少一个神经靶标来治疗所述癫痫事件。 一种用于存储当由处理器执行时执行该方法的指令的非传递式计算机可读存储设备。 适用于该方法的医疗装置系统。

    CONTIGENT ACQUISITION AND ANALYSIS OF BIOLOGICAL SIGNAL OR FEATURE THEREOF FOR EPILEPTIC EVENT DETECTION
    87.
    发明申请
    CONTIGENT ACQUISITION AND ANALYSIS OF BIOLOGICAL SIGNAL OR FEATURE THEREOF FOR EPILEPTIC EVENT DETECTION 审中-公开
    生物学信号或其特征的连续获取和分析，用于异常事件检测

    公开(公告)号：US20140276129A1

    公开(公告)日：2014-09-18

    申请号：US14205164

    申请日：2014-03-11

    Applicant: Flint Hills Scientific, L.L.C.

    Inventor： Ivan Osorio

    IPC: A61B5/00 ,  A61B5/04

    Abstract: We report a method comprising receiving a first indication to gather a first biological signal or feature thereof from a patient; gathering the first biological signal or feature thereof; receiving a second indication to stop gathering the first biological signal or feature thereof, wherein the second indication relates to a detection of an end of a brain state change; and stopping gathering the first biological signal or feature thereof. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

    Abstract translation: 我们报告一种方法，包括接收从患者收集第一生物信号或其特征的第一指示; 收集第一生物信号或其特征; 接收第二指示以停止收集第一生物信号或其特征，其中所述第二指示涉及脑状态改变的结束的检测; 并停止收集第一生物信号或其特征。 我们还报告配置为实施该方法的医疗设备系统。 我们还报告了一种非暂时性的计算机可读程序存储单元，其中编码有指令，当由计算机执行时，执行该方法。

    PATHOLOGICAL STATE DETECTION USING DYNAMICALLY DETERMINED BODY INDEX RANGE VALUES
    88.
    发明申请
    PATHOLOGICAL STATE DETECTION USING DYNAMICALLY DETERMINED BODY INDEX RANGE VALUES 审中-公开
    使用动态确定的身体指数范围值进行病理状态检测

    公开(公告)号：US20140275828A1

    公开(公告)日：2014-09-18

    申请号：US14084513

    申请日：2013-11-19

    Applicant: Flint Hills Scientific, L.L.C.

    Inventor： Ivan Osorio

    IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/22 ,  A61B5/0488 ,  A61B5/01 ,  A61B5/04 ,  A61B5/11 ,  A61B5/145

    Abstract: We report method of detecting a pathological body state of a patient, comprising receiving a body signal of the patient; determining a body index from said body signal; determining an activity level of said patient; determining a value range for said body index for said patient, based at least in part on said activity level; comparing said body index to said value range; and detecting a pathological state when said body index is outside said value range. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

    Abstract translation: 我们报告检测患者的病理体状态的方法，包括接收患者的身体信号; 从所述身体信号确定身体指数; 确定所述患者的活动水平; 至少部分地基于所述活动水平确定所述患者的身体指数的值范围; 将身体指数与所述值范围进行比较; 以及当所述身体指数在所述值范围之外时检测病理状态。 我们还报告配置为实施该方法的医疗设备系统。 我们还报告了一种非暂时性的计算机可读程序存储单元，其中编码有指令，当由计算机执行时，执行该方法。

    System and Apparatus for Automated Quantitative Assessment, Optimization and Logging of the Effects of a Therapy
    89.
    发明申请
    System and Apparatus for Automated Quantitative Assessment, Optimization and Logging of the Effects of a Therapy 有权
    用于自动定量评估，优化和记录治疗效果的系统和装置

    公开(公告)号：US20140052213A1

    公开(公告)日：2014-02-20

    申请号：US14034292

    申请日：2013-09-23

    Applicant: Flint Hills Scientific, L.L.C.

    Inventor： Ivan Osorio

    IPC: A61N1/36

    CPC classification number: A61N1/36064 ,  A61B5/0476 ,  A61B5/4094 ,  A61B5/4848 ,  A61N1/0529 ,  A61N1/36114 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/3621

    Abstract: A method for assessment, optimization and logging of the effects of a therapy for a medical condition, including (a) receiving into a signal processor input signals indicative of the subject's brain activity; (b) characterizing the spatio-temporal behavior of the brain activity using the signals; (c) delivering a therapy to a target tissue of the subject; (d) characterizing the spatio-temporal effect of the therapy on the brain activity; (e) in response to the characterizing, optimizing at least one parameter of the therapy if the brain activity has not been satisfactorily modified and/or has been adversely modified by the therapy; (f) characterizing the spatio-temporal effect of the at least one optimized parameter; and (g) logging to memory the at least one optimized parameter. A computer readable program storage unit encoded with instructions that, when executed by a computer, performs the method.

    Abstract translation: 一种用于评估，优化和记录治疗对于医​​疗状况的影响的方法，包括（a）接收信号处理器输入指示受试者大脑活动的信号; （b）使用信号表征大脑活动的时空行为; （c）向受试者的靶组织递送治疗; （d）描述治疗对大脑活动的时空影响; （e）响应于特征，如果脑活动未被令人满意地修改和/或已被治疗不利地修饰，则优化治疗的至少一个参数; （f）表征所述至少一个优化参数的时空效应; 和（g）将至少一个优化参数记录到存储器。 一种计算机可读程序存储单元，其编码有当由计算机执行时执行该方法的指令。

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