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134 条记录 (耗时 0.043 秒)

    Ortho-substituted pentafluorosulfanyl benzenes, method for the production thereof and their use as synthesis intermediates
    81.
    发明授权
    Ortho-substituted pentafluorosulfanyl benzenes, method for the production thereof and their use as synthesis intermediates 失效
    正取代的五氟硫烷基苯，其制备方法及其作为合成中间体的用途

    公开(公告)号：US07763661B2

    公开(公告)日：2010-07-27

    申请号：US11684259

    申请日：2007-03-09

    申请人： Heinz-Werner Kleemann ,  Remo Weck

    发明人： Heinz-Werner Kleemann ,  Remo Weck

    IPC分类号： A61K31/095 ,  C07C321/00

    CPC分类号： C07C381/00

    摘要： This invention relates to novel substituted pentafluorosulfanylbenzenes of the formula I: and/or salts thereof as claimed, for use as a synthetic intermediates for preparing medicaments, diagnostic aids, liquid crystals, pesticides, herbicides, fungicides, nematicides, parasiticides, insecticides, acaricides, arthropodicides and polymers.

    摘要翻译： 本发明涉及用作制备药物，诊断助剂，液晶，农药，除草剂，杀真菌剂，杀线虫剂，杀寄生物剂，杀虫剂，杀螨剂等的合成中间体的式I的取代五氟硫烷基苯和/或其盐， 杀虫剂和聚合物。

    Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives
    82.
    发明授权
    Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives 有权
    制备（3-氧代-2,3-二氢-1H-异吲哚-1-基）乙酰基胍衍生物的方法

    公开(公告)号：US07531569B2

    公开(公告)日：2009-05-12

    申请号：US11001624

    申请日：2004-12-01

    申请人： Gerrit Schubert ,  Joerg Rieke-Zapp ,  Johannes Keil ,  Heinz-Werner Kleemann ,  Reda Hanna ,  Bao-Guo Huang ,  Xiao-Dong Wu ,  Yves Gouraud

    发明人： Gerrit Schubert ,  Joerg Rieke-Zapp ,  Johannes Keil ,  Heinz-Werner Kleemann ,  Reda Hanna ,  Bao-Guo Huang ,  Xiao-Dong Wu ,  Yves Gouraud

    IPC分类号： A61K31/4035 ,  C07D209/46 ,  C07C229/38

    CPC分类号： A61K31/4035

    摘要： A method and apparatus for preventing board warpage during the application and curing or drying of liquid epoxies, or the like, on printed circuit boards using a clamping fixture assembly, which includes at least one clamping fixture support and at least one clamping fixture overlay. If desired, a plurality of printed circuit boards may be processed using an appropriate clamping fixture assembly. Furthermore, the clamping fixture may be constructed so a slight bow or curvature thereof can counter either a convex or concave bow or curvature of the printed circuit board.In the method, at least one printed circuit board is mounted to a clamping fixture support whereby a clamping fixture overlay is placed on top of the first printed circuit board.

    摘要翻译： 一种用于在使用夹紧夹具组件的印刷电路板上施加和固化或干燥液体环氧树脂等期间防止板翘曲的方法和装置，其包括至少一个夹紧夹具支架和至少一个夹紧固定盖。 如果需要，可以使用适当的夹具组件来处理多个印刷电路板。 此外，夹持夹具可以被构造成轻微的弓形或其曲率可以对抗印刷电路板的凸形或凹形弓形或曲率。 在该方法中，至少一个印刷电路板安装到夹具固定支架上，由此夹紧夹具覆盖物放置在第一印刷电路板的顶部上。

    PENTAFLUOROSULFANYLBENZOYLGUANIDINES, PROCESS FOR THEIR PREPARATION, USE AS A MEDICAMENT OR DIAGNOSTIC AID, AND MEDICAMENT COMPRISING SAME
    83.
    发明申请
    PENTAFLUOROSULFANYLBENZOYLGUANIDINES, PROCESS FOR THEIR PREPARATION, USE AS A MEDICAMENT OR DIAGNOSTIC AID, AND MEDICAMENT COMPRISING SAME 有权
    二苯并呋喃基苯甲酰胺，其制备方法，用作药物或诊断辅助药物，以及包含其的药物

    公开(公告)号：US20080146673A1

    公开(公告)日：2008-06-19

    申请号：US11972954

    申请日：2008-01-11

    申请人： Heinz-Werner KLEEMANN

    发明人： Heinz-Werner KLEEMANN

    IPC分类号： A61K31/155 ,  C07C277/08 ,  A01N1/02 ,  A61P9/10 ,  A61P41/00 ,  A61P39/00

    CPC分类号： C07C381/00

    摘要： Pentafluorosulfanylbenzoylguanidines of formula I wherein R1 to R4 have the meanings stated in the claims, are suitable, for example, as antiarrhythmic medicaments with a cardioprotective component for the prophylaxis of infarction and treatment of infarction and for the treatment of angina pectoris. They also inhibit preventively the pathophysiological processes associated with the development of ischemia-induced damage, especially in the triggering of ischemia-induced cardiac arrhythmias.

    摘要翻译： 其中R 1至R 4具有权利要求中所述含义的式I的五氟硫烷基苯甲酰基胍适用于例如具有用于预防梗塞和治疗梗塞和用于治疗心绞痛的心脏保护组分的抗心律失常药物。 它们还预防性地抑制与缺血诱导的损伤的发展相关的病理生理过程，特别是在引发缺血诱发的心律失常中。

    Process for preparing 4-pentafluorosulfanylbenzoylguanidines
    85.
    发明授权
    Process for preparing 4-pentafluorosulfanylbenzoylguanidines 有权
    制备4-五氟硫基苯甲酰基胍的方法

    公开(公告)号：US07126026B2

    公开(公告)日：2006-10-24

    申请号：US10988971

    申请日：2004-11-15

    申请人： Gerrit Schubert ,  Heinz-Werner Kleemann

    发明人： Gerrit Schubert ,  Heinz-Werner Kleemann

    IPC分类号： C07C233/65

    CPC分类号： C07C381/00

    摘要： A process for preparing 4-pentafluorosulfanylbenzoylguanidines of formula I wherein R1 to R4 have the meanings indicated in the specification. The compounds of formula I are NHE1 inhibitors and can be employed, for example, for the treatment of cardiovascular disorders.

    摘要翻译： 一种制备式I的4-五氟硫烷基苯甲酰胍的方法，其中R1至R4具有说明书中所示的含义。 式I化合物是NHE1抑制剂，可用于例如治疗心血管疾病。