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公开(公告)号：US20210260292A1
公开(公告)日：2021-08-26
申请号：US17260411
申请日：2019-07-15
申请人： Sanofi
发明人： David Aubrey Plumptre , Robert Veasey , Paul Griffin , Rory James Livingston Hawkins , Tom Alexander Earwalker
IPC分类号： A61M5/24
摘要： A drug delivery device is proposed, comprising: a housing; a drive mechanism; a cartridge containing a drug, the cartridge being retained in a defined position relative to the housing, wherein the drive mechanism is configured to dispense drug from the cartridge; a cartridge bias system, which comprises at least one resilient member and at least one rigid force transfer body, wherein the rigid force transfer body is movably retained in the housing, wherein the cartridge bias system is arranged and configured to exert a force on the cartridge to maintain the cartridge in the defined position, wherein the force is provided by the at least one resilient member, and wherein the rigid force transfer body is operatively connected to the at least one resilient member such that the force is reacted by the rigid force transfer body. Further, a method to modify a drug delivery device is disclosed.
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公开(公告)号：US11090436B2
公开(公告)日：2021-08-17
申请号：US15557338
申请日：2016-03-11
申请人： SANOFI
发明人： Richard James Vincent Avery , Matthew Meredith Jones , William Marsh , Anthony Paul Morris , David Aubrey Plumptre , Samuel Keir Steel , Robert Frederick Veasey
摘要： The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing. The device further comprises a monitoring device, wherein at least one component part of the device is diaphanous to allow optical detection of the movements of the at least two separate component parts relative to the housing, relative to the monitoring device and/or relative to each other during dose setting and/or during dose dispensing by the monitoring device.
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73.发明申请公开(公告)号：US20200316306A1
公开(公告)日：2020-10-08
申请号：US16303462
申请日：2017-05-29
摘要： A button for setting and dispensing a dose of a drug from a drug delivery device is described. The button comprises a plastic component and a metal component, wherein the plastic component is at least partly received by the metal component, and wherein the metal component is configured to be manipulated by a user for setting and dispensing the dose. Furthermore, a method for assembling a button for a drug delivery device and a drug delivery device comprising the button are described.
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公开(公告)号：US10744270B2
公开(公告)日：2020-08-18
申请号：US15528289
申请日：2015-11-24
申请人： Sanofi
发明人： Richard James Vincent Avery , Matthew Meredith Jones , William Geoffrey Arthur Marsh , Anthony Paul Morris , David Aubrey Plumptre , Samuel Keir Steel , Robert Frederick Veasey
摘要： A dose setting mechanism comprising a first element and a second element; the first element being moveable with respect to the second element; the first element and the second element being coupled by a ratchet mechanism allowing motion of the first element with respect to the second element from a first position to a second position only in a first direction while preventing motion in a second direction that is opposite to the first direction; once passing the second position, the first element being moveable with respect to the second element in the first direction and in the second direction.
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公开(公告)号：US10744269B2
公开(公告)日：2020-08-18
申请号：US14888724
申请日：2014-05-02
摘要： A supplemental device for attachment to an injection device, the supplemental device comprising: an electromechanical switch arrangement having an open state and a closed state, the electromechanical switch arrangement comprising a protrusion configured to contact a surface of the injection device when a dose of zero units is dialled into the injection device, wherein the state of the switch arrangement is configured to change when a dose dialled into the attached injection device is decreased from one unit to zero units; and a processor arrangement configured to: detect one or more changes in the state of the electromechanical switch arrangement; and determine from the one or more state changes that a dose of zero units is dialled into the injection device.
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公开(公告)号：US10525205B2
公开(公告)日：2020-01-07
申请号：US15313900
申请日：2015-05-27
发明人： Matthew Jones , Samuel Steel , Neal Alexander Blundred , Joseph Butler , Robert Veasey , David Aubrey Plumptre
摘要： A dispense mechanism for a drug delivery device for the delivery of a primary medicament in a primary cartridge and a secondary medicament in a secondary cartridge includes a primary drive member and a secondary drive member serve for driving a primary and a secondary lead screw. The primary drive member and the secondary drive member are configured to rotate during dose dispense. A coupling member serves for rotationally coupling the primary drive member to the secondary drive member and moves from a first position in which the primary drive member is rotationally decoupled from the secondary drive member into a second position in which the primary drive member is rotationally coupled to the secondary drive member during dose dispense. Rotation of the primary drive member moves the coupling member from the first position into the second position.
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公开(公告)号：US20200001020A1
公开(公告)日：2020-01-02
申请号：US16490759
申请日：2018-03-07
IPC分类号： A61M5/32
摘要： A multi-part cap assembly for a drug delivery device is provided, the cap assembly comprising: a first cap component, and a second cap component, wherein the first cap component is assembled to the second cap component, wherein one of the first cap component and the second cap component is provided with a guide track and the other one of the first cap component and the second cap component is provided with a guide feature, wherein the guide track and the guide feature are arranged to cooperate to form an axial guiding interface between the first cap component and the second cap component, and wherein the axial guiding interface is configured such that relative rotational movement between the first cap component and the second cap component is restricted or prevented. Furthermore, a kit for assembling a cap and a method for assembling a cap are provided as well as a drug delivery device.
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公开(公告)号：US20190351141A1
公开(公告)日：2019-11-21
申请号：US16528080
申请日：2019-07-31
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
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公开(公告)号：US10420897B2
公开(公告)日：2019-09-24
申请号：US14783174
申请日：2014-05-02
IPC分类号： A61M5/315
摘要： A supplemental device for attachment to an injection device, the supplemental device having a housing containing at least two electromechanical switches each having an open state and a closed state and a protrusion associated with each switch configured to protrude from the housing so as to contact a rotatable surface of the injection device while the supplemental device is attached to the injection device; and a processor arrangement configured to detect a change in the state of each of the switches; and to determine a direction of rotation of the rotatable surface of the injection device from the detected state changes.
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公开(公告)号：US10293112B2
公开(公告)日：2019-05-21
申请号：US15137262
申请日：2016-04-25
摘要： The invention relates to a disposable drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a cartridge holder for retaining a cartridge containing the medicament, a piston rod displaceable relative to the cartridge holder, a driver coupled to the piston rod, a display member for indicating a set dose and being coupled to the housing and to the driver, and a button coupled to the display member and to the driver.
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