公开(公告)号：US20120149753A1

公开(公告)日：2012-06-14

申请号：US13398278

申请日：2012-02-16

Applicant: Yueh-Hsiung Kuo ,  Bi-Fong Lin

Inventor： Yueh-Hsiung Kuo ,  Bi-Fong Lin

IPC: A61K31/4015 ,  A61K31/235 ,  A61P29/00 ,  A61K31/34

CPC classification number: C07D207/40 ,  C07D207/444 ,  C07D307/60

Abstract: Disclosed herein are isolated compounds or pharmaceutically acceptable salts thereof, which exhibit immunostimulatory or anti-inflammatory effects. The compounds are isolated from the fruiting body of A. camphorata in a solid culture. Also disclosed are methods of stimulating immune responses and/or treating an inflammatory disorder with these compounds and pharmaceutical compositions including the compounds or pharmaceutically acceptable salts thereof.

Abstract translation: 本文公开了显示免疫刺激或抗炎作用的分离的化合物或其药学上可接受的盐。 化合物在固体培养物中从樟芝的子实体中分离出来。 还公开了用这些化合物和药物组合物刺激免疫应答和/或治疗炎性病症的方法，包括其化合物或其药学上可接受的盐。

公开(公告)号：US08148420B2

公开(公告)日：2012-04-03

申请号：US12956897

申请日：2010-11-30

Applicant: Yueh-Hsiung Kuo ,  Bi-Fong Lin

Inventor： Yueh-Hsiung Kuo ,  Bi-Fong Lin

IPC: A61K31/4015 ,  A61K31/341 ,  A61K31/216

CPC classification number: C07D207/40 ,  C07D207/444 ,  C07D307/60

Abstract: Methods of stimulating immune response or treating an inflammatory disorder with one of a number of the compounds disclosed herein or a pharmaceutically acceptable salt thereof.

Abstract translation: 用本文公开的许多化合物之一或其药学上可接受的盐刺激免疫应答或治疗炎性病症的方法。

公开(公告)号：US20110218415A1

公开(公告)日：2011-09-08

申请号：US13127617

申请日：2009-10-28

Applicant: Peng-Sheng Chen ,  Shien-Fong Lin

Inventor： Peng-Sheng Chen ,  Shien-Fong Lin

IPC: A61M5/00 ,  A61N1/365 ,  A61N1/39 ,  A61B5/04

CPC classification number: A61B5/04001 ,  A61B5/6846 ,  A61N1/3624 ,  A61N1/395

Abstract: A method has been developed that detects cardiac arrhythmia from intrinsic cardiac nerve signals obtained from a heart in a patient. The method includes sampling intrinsic cardiac nerve activity at a high sample rate, filtering the sampled signal with a high pass filter, comparing the filtered signal to a predetermined threshold, and initiating a therapeutic action in response to the filtered signal exceeding the predetermined threshold. The intrinsic cardiac nerve activity may be received through an electrode implanted on the heart or from an electrode inserted into the venous structure of the heart.

Abstract translation: 已经开发了一种从患者心脏获得的内在心脏神经信号中检测心律失常的方法。 该方法包括以高采样率对固有的心脏神经活动进行采样，用高通滤波器对采样信号进行滤波，将滤波的信号与预定的阈值进行比较，以及响应于经过滤波的信号超过预定阈值启动治疗动作。 可以通过植入在心脏上的电极或插入到心脏静脉结构中的电极来接收固有的心脏神经活动。

公开(公告)号：US07902384B2

公开(公告)日：2011-03-08

申请号：US12418490

申请日：2009-04-03

Applicant: Ching-Jang Huang ,  Ssu-Ching Wang ,  Yueh-Hsiung Kuo ,  Yong-Han Hong ,  Bi-Fong Lin ,  Chin Hsu

Inventor： Ching-Jang Huang ,  Ssu-Ching Wang ,  Yueh-Hsiung Kuo ,  Yong-Han Hong ,  Bi-Fong Lin ,  Chin Hsu

IPC: C07D315/00

CPC classification number: C07D307/83 ,  A23L33/105 ,  A61K31/343 ,  C07D309/30

Abstract: The present invention relates to compounds having estrogenic activity selected from the group consisting of Loliolide, (4S,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one, (4R,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one and analogues thereof. The compounds of the present invention are selective estrogen receptor modulator, which can selectively activate ERβ and simultaneously express high estrogenic activity, and also can be applied as medical or food compositions to improve estrogen deficiency-related symptoms.

Abstract translation: 本发明涉及具有选自下组的雌激素活性的化合物：（L，R），（4S，6S）-4-羟基-6-十九烷基 - 四氢吡喃-2-酮，（4R，6S）-4-羟基-6 - 十二烷基 - 四氢 - 吡喃-2-酮及其类似物。 本发明的化合物是选择性雌激素受体调节剂，其可以选择性地激活ER和bgr; 同时表现出较高的雌激素活性，也可用作医药或食品组合物，以改善与雌激素缺乏有关的症状。

公开(公告)号：US20100214217A1

公开(公告)日：2010-08-26

申请号：US12003227

申请日：2007-12-20

Applicant: Hao Fong Lin

Inventor： Hao Fong Lin

IPC: G06F3/033 ,  G06F21/00

CPC classification number: G06F3/03543 ,  G06F21/34

Abstract: A theme changeable mouse for automatically matching network communities is provided and can automatically match and link users of individually customized theme website communities by built-in IDs (identifications). The mouse includes a theme cover and a mouse base. The theme cover can be optionally matched and changed, while each of the theme cover has the IDs therein. A recognition processing unit of a control circuit firmware on a printed circuit board in the mouse base is used to execute a recognition process, so that the user can automatically log into a specific website for providing advanced information service if the user is matched.

Abstract translation: 提供用于自动匹配网络社区的主题更改鼠标，并可通过内置ID（标识）自动匹配和链接单独定制的主题网站社区的用户。 鼠标包括主题封面和鼠标底座。 主题封面可以选择匹配和更改，而每个主题封面都有ID。 使用鼠标基板上的印刷电路板上的控制电路固件的识别处理单元执行识别处理，从而如果用户匹配，用户可以自动登录到特定网站以提供高级信息服务。

公开(公告)号：US20090179216A1

公开(公告)日：2009-07-16

申请号：US12351815

申请日：2009-01-10

Applicant: Rong Xuan ,  Chih-Hao Hsu ,  Wen-Yung Yeh ,  Chen-Peng Hsu ,  Chen-Kun Chen ,  Kun-Fong Lin

Inventor： Rong Xuan ,  Chih-Hao Hsu ,  Wen-Yung Yeh ,  Chen-Peng Hsu ,  Chen-Kun Chen ,  Kun-Fong Lin

IPC: H01L33/00

CPC classification number: H01L33/0004 ,  H01L25/0753 ,  H01L33/64 ,  H01L2224/48091 ,  H01L2224/73265 ,  H01L2924/00014

Abstract: A light emitting device with magnetic field includes a light emitting device, a thermal conductive material layer and a magnetic layer. The thermal conductive material layer is coupled with the light emitting device to dissipate heat generated by the light emitting device. The magnetic layer is coupled with thermal conductive material layer to produce a magnetic filed on the light emitting device.

Abstract translation: 具有磁场的发光器件包括发光器件，导热材料层和磁性层。 导热材料层与发光器件耦合以散发由发光器件产生的热量。 磁性层与导热材料层耦合以在发光器件上产生磁场。

公开(公告)号：US20090044586A1

公开(公告)日：2009-02-19

申请号：US11840071

申请日：2007-08-16

Applicant: Wei-Fong LIN ,  Wei-Yuan Peng ,  Min-Hsi Lin ,  Shao-Tzu Hsu

Inventor： Wei-Fong LIN ,  Wei-Yuan Peng ,  Min-Hsi Lin ,  Shao-Tzu Hsu

IPC: B21H5/00

CPC classification number: B21H5/00 ,  Y10T74/19679 ,  Y10T403/4381 ,  Y10T403/53 ,  Y10T403/606 ,  Y10T403/7016

Abstract: A gear-rolling apparatus includes two gear units and a base. Each gear unit has a rolling portion, a rolling shaft extends from the rolling portion, a clicking column and two location columns extend from edges of a free end of the rolling shaft along an axle direction of the rolling shaft. The clicking column and the two location columns are spaced out from each other to form three grooves therebetween, a clicking clasp extends inward from the top of the clicking column. The clicking clasp has an inclined inner surface which inclines inward from top to bottom. The two rolling shafts are inserted into the hole of the base, the clicking column of one of the rolling shafts mates the groove opened between the location columns of the other rolling shaft, the location columns of one of the rolling shafts mate the grooves opened between the clicking column and the location columns of the other rolling shaft respectively, bottom surfaces of the two clicking clasps are against each other.

Abstract translation: 齿轮滚动装置包括两个齿轮单元和一个底座。 每个减速器具有滚动部分，滚动轴从滚动部分延伸，一个咔哒声柱和两个位置列沿滚动轴的车轴方向从滚动轴的自由端的边缘延伸。 点击列和两个位置列彼此间隔开，在其间形成三个凹槽，点击扣从点击列的顶部向内延伸。 点击扣具有从上到下倾斜的倾斜内表面。 两个滚动轴插入基座的孔中，其中一个滚动轴的止动柱与在另一个滚动轴的定位柱之间打开的凹槽配合，一个滚动轴的位置列与第二滚动轴之间打开的凹槽配合， 分别是另一个滚动轴的点击列和位置列，两个点击扣的底部表面彼此相对。

公开(公告)号：US07446096B2

公开(公告)日：2008-11-04

申请号：US11303934

申请日：2005-12-19

Applicant: Ae-June Wang ,  Chi-Heng Jian ,  Shyh-Dar Li ,  Yi-Fong Lin ,  Shih-Jr Liu

Inventor： Ae-June Wang ,  Chi-Heng Jian ,  Shyh-Dar Li ,  Yi-Fong Lin ,  Shih-Jr Liu

IPC: A61K38/00

CPC classification number: A61K9/127 ,  A61K38/063 ,  A61K47/6911 ,  Y10S977/773

Abstract: A delivery system. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound including a moiety comprising a vitamin E derivative or a phospholipid derivative, a polyethylene glycol (PEG) or a polyethylene glycol derivative bonded thereto, and a glutathione (GSH) or a glutathione derivative bonded to the polyethylene glycol or the polyethylene glycol derivative.

Abstract translation: 送货系统。 递送系统包括载体或活性化合物和接枝在其上的谷胱甘肽或谷胱甘肽衍生物。 本发明还提供了包含包含维生素E衍生物或磷脂衍生物，聚乙二醇（PEG）或与其结合的聚乙二醇衍生物的部分的化合物以及与聚乙二醇结合的谷胱甘肽（GSH）或谷胱甘肽衍生物 聚乙二醇衍生物。

公开(公告)号：US06916208B2

公开(公告)日：2005-07-12

申请号：US10721279

申请日：2003-11-26

Applicant: Chien-An Chen ,  Yu-Fong Lin

Inventor： Chien-An Chen ,  Yu-Fong Lin

IPC: G06K7/00 ,  H01R25/00 ,  H01R27/02 ,  H01R31/00 ,  H01R33/88 ,  H01R33/92 ,  H01R33/94 ,  H02J7/00 ,  H04M1/725

CPC classification number: G06K7/00 ,  H02J7/0044 ,  H04M1/72527

Abstract: A compact card reader is described. The compact card reader has a charging circuit and a cellular phone-connecting slot to enable the compact card reader to save/retrieve data to/from a memory card or a cellular phone, at the same time charge the cellular phone and the cellular phone battery in order to reduce the operation cost and this also increases the speed of the data processing.

Abstract translation: 描述了小型读卡器。 紧凑型读卡器具有充电电路和蜂窝电话连接槽，以使小型读卡器能够从存储卡或蜂窝电话保存/取回数据，同时为蜂窝电话和蜂窝电话电池充电 为了降低运营成本，这也提高了数据处理的速度。

公开(公告)号：US20050142207A1

公开(公告)日：2005-06-30

申请号：US11024904

申请日：2004-12-29

Applicant: Ae-June Wang ,  Yi-Fong Lin ,  Chi-Heng Jian ,  Pei-Lin Wang ,  Shin-Jr Liu

Inventor： Ae-June Wang ,  Yi-Fong Lin ,  Chi-Heng Jian ,  Pei-Lin Wang ,  Shin-Jr Liu

IPC: A61K9/127 ,  A61K9/16 ,  B01J13/14 ,  A61K9/14 ,  A61K9/50

CPC classification number: B01J13/14 ,  A61K9/127 ,  A61K9/1635 ,  A61K9/1652

Abstract: A method for preparing polymeric microsphere by an aqueous two phase emulsion process. A first polymer aqueous solution is provided and the first polymer includes a functional group capable of forming cross-linking. A second polymer aqueous solution is provided, which is acidic and miscible with the first polymer aqueous solution. The first and second polymer aqueous solutions are mixed and stirred to form an emulsion, such that the first polymer solution forms a dispersed phase in a continuous phase of the second polymer solution. The dispersed phase includes a plurality of the first polymeric microsphere, and a solidification film formed by cross-linking of the functional group constitutes a microsphere surface. Finally, the first polymeric microsphere are separated out.

Abstract translation: 一种通过水相双相乳液法制备聚合物微球的方法。 提供第一聚合物水溶液，并且第一聚合物包括能够形成交联的官能团。 提供第二聚合物水溶液，其与第一聚合物水溶液呈酸性并可混溶。 将第一和第二聚合物水溶液混合并搅拌以形成乳液，使得第一聚合物溶液在第二聚合物溶液的连续相中形成分散相。 分散相包括多个第一聚合物微球，并且通过官能团交联形成的固化膜构成微球表面。 最后，分离第一个聚合物微球。