公开(公告)号：US4066692A

公开(公告)日：1978-01-03

申请号：US669118

申请日：1976-03-22

Applicant: Edward J. Cragoe, Jr. ,  John B. Bicking ,  Robert L. Smith

Inventor： Edward J. Cragoe, Jr. ,  John B. Bicking ,  Robert L. Smith

IPC: C07C49/16 ,  C07C49/227 ,  C07C59/215 ,  C07C245/18 ,  C07D303/38 ,  C07F9/54 ,  C07C59/00

CPC classification number: C07D303/38 ,  C07C245/18 ,  C07C59/215 ,  C07F9/5407 ,  Y10S514/929

Abstract: This invention relates to 11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of hypertension, for the prevention of thrombus formation, in preventing gastric secretion, and as regulators of the immune response.

公开(公告)号：US3897478A

公开(公告)日：1975-07-29

申请号：US3920270

申请日：1970-05-21

Applicant: STAUFFER CHEMICAL CO

Inventor： SHIM KYUNG S ,  MARTIN DONALD J

IPC: C07C245/18 ,  C07C67/00

CPC classification number: C07C245/18

Abstract: A continuous process for the preparation of the C1-C10 alkyl chrysanthemate esters is disclosed. The use of this novel process is found to be far more rapid as well as less hazardous than the batch-type process presently employed for the preparation of alkyl chrysanthemate esters while also producing the latter esters in yields which are substantially greater than those attainable by means of this batch-type process.

Abstract translation: 公开了用于制备C1-C10烷基菊酸酯的连续方法。 发现这种新方法的使用比目前用于制备烷基菊酸酯的间歇式方法更加快速和危险性更低，同时产生后者酯的产率，其显着大于可通过手段获得的那些 的这种批量过程。

公开(公告)号：US2965636A

公开(公告)日：1960-12-20

申请号：US70896958

申请日：1958-01-15

Applicant: PARKE DAVIS & CO

Inventor： MOORE ALEXANDER M ,  DE WALD HORACE A

IPC: C07C245/18

CPC classification number: C07C245/18

公开(公告)号：US2965635A

公开(公告)日：1960-12-20

申请号：US70896858

申请日：1958-01-15

Applicant: PARKE DAVIS & CO

Inventor： MOORE ALEXANDER M ,  DE WALD HORACE A

IPC: C07C245/18

CPC classification number: C07C245/18

公开(公告)号：US2878245A

公开(公告)日：1959-03-17

申请号：US70897058

申请日：1958-01-15

Applicant: PARKE DAVIS & CO

Inventor： MOORE ALEXANDER M ,  DE WALD HORACE A

IPC: C07C245/18 ,  C07D263/44

CPC classification number: C07D263/44 ,  C07C245/18