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61.发明授权公开(公告)号：US09370345B2
公开(公告)日：2016-06-21
申请号：US13744018
申请日：2013-01-17
IPC分类号： A61B17/00
CPC分类号： A61B17/00491 , A61B17/0057 , A61B2017/0065 , Y10T29/49826
摘要： A bioadhesive delivery catheter includes a manifold, a dual lumen tube, and a mixing member. The manifold includes a delivery device passage and an injection port. The tube is insertable into the delivery device passage and includes first and second lumens positioned side-by-side. The first lumen extends proximal of the second lumen within the delivery device passage, and the second lumen is in flow communication with the injection port. The mixing member is positioned between a proximal inlet of the injection port and the second lumen and is configured to help mix a bioadhesive material that is delivered through the injection port into the second lumen.
摘要翻译： 生物粘附递送导管包括歧管，双腔管和混合构件。 歧管包括输送装置通道和注射口。 管可插入输送装置通道中并且包括并排定位的第一和第二管腔。 第一腔在输送装置通道内延伸到第二腔的近端，并且第二腔与注射口流动连通。 混合构件位于注射口的近侧入口和第二腔之间，并且构造成帮助将通过注射口输送的生物粘附材料混合到第二腔中。
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公开(公告)号：US09358077B2
公开(公告)日：2016-06-07
申请号：US13770889
申请日：2013-02-19
发明人： Zachary J. Tegels
CPC分类号： A61B17/0469 , A61B17/0057 , A61B17/0467 , A61B17/0482 , A61B17/0485 , A61B17/0487 , A61B90/06 , A61B2017/00371 , A61B2017/00663 , A61B2017/00778 , A61B2017/0488 , A61B2090/062
摘要： A vascular closure assembly configured to seal a puncture in a vessel that is accessible through a tissue tract. The vascular closure assembly includes a vascular closure device comprising a handle assembly, an insertion shaft, an anchor assembly, and at least one suture member. The insertion shaft extends distally from the handle assembly and carries a plurality of needles. The needles are operable to position at least one suture across the vessel puncture. The anchor assembly is positioned distal of the insertion shaft. The at least one suture member is positioned distal of the insertion shaft. The insertion shaft extends into the tissue tract to position the anchor assembly through the puncture and into the vessel and includes a first depth indicator on an outer surface thereof that indicates a depth of the tissue tract.
摘要翻译： 一种血管闭合组件，其构造成密封可通过组织管道接近的容器中的穿刺。 血管闭合组件包括血管闭合装置，其包括手柄组件，插入轴，锚固组件和至少一个缝合构件。 插入轴从手柄组件向远侧延伸并且携带多个针。 针可操作以将至少一条缝合线定位穿过血管穿刺。 锚固组件位于插入轴的远侧。 至少一个缝合构件定位在插入轴的远侧。 插入轴延伸到组织管道中以将锚固组件定位穿过穿刺并进入容器，并且在其外表面上包括指示组织管道深度的第一深度指示器。
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公开(公告)号：US09131932B2
公开(公告)日：2015-09-15
申请号：US13757238
申请日：2013-02-01
发明人： Zachary J. Tegels
CPC分类号： A61B17/0057 , A61B2017/00663 , A61B2017/00672 , A61B2017/0417 , A61B2017/0496
摘要： A vascular closure device includes a carrier tube and a sleeve. The carrier tube includes at least first and second lumens, the first lumen being configured to hold a sealing member, the second lumen being configured to provide blood flow from a distal opening thereof to a proximal opening thereof. The sleeve is positioned on the carrier tube and movable from a first position wherein blood flow through the second lumen is unobstructed, and a second position covering the distal and proximal openings to block blood flow through the second lumen.
摘要翻译： 血管闭合装置包括载体管和套管。 所述载体管包括至少第一和第二腔，所述第一腔构造成保持密封构件，所述第二腔构造成将血流从其远端开口提供到其近侧开口。 套筒定位在承载管上并且可以从第一位置移动，其中通过第二内腔的血液流动畅通无阻，而第二位置覆盖远侧和近侧开口以阻止血流通过第二腔。
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公开(公告)号：US20140257371A1
公开(公告)日：2014-09-11
申请号：US13787470
申请日：2013-03-06
发明人： Zachary J. Tegels
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00526 , A61B2017/0065 , A61B2017/00654 , A61B2017/00672
摘要： A vascular closure device includes a catheter, a balloon, an introducer, and a guidewire lumen. The catheter includes an inflation lumen. The balloon is positioned at a distal end portion of the catheter. The introducer is positioned distal of the balloon. The guidewire lumen extends along at least a portion of the introducer and terminates at a rapid exchange port positioned distal of the balloon. The guidewire lumen is receptive of a guidewire to guide the catheter through a vessel puncture in a vessel to position the balloon within the vessel.
摘要翻译： 血管闭合装置包括导管，气囊，导引器和导丝管腔。 导管包括充气腔。 气囊位于导管的远端部分。 引导器位于气囊的远侧。 导丝腔沿引导器的至少一部分延伸并终止于位于气囊远端的快速交换口。 导丝腔容纳导丝，以引导导管通过容器在容器中穿刺以将气囊定位在血管内。
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公开(公告)号：US20140236224A1
公开(公告)日：2014-08-21
申请号：US13773197
申请日：2013-02-21
发明人： Zachary J. Tegels
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00557 , A61B2017/0065 , A61B2017/00654
摘要： A vascular closure system includes a carrier tube, an expandable anchor, a bioadhesive material, a sealing tip, and a filament. The expandable anchor is mounted to the carrier tube and configured to extend through a vessel puncture to temporarily seal the vessel puncture from within a vessel. The bioadhesive material is disposed outside of the vessel and configured to seal the vessel puncture. The sealing tip is mounted to the carrier tube distal of the expandable anchor. The filament is connected to and extends proximally from the sealing tip. Applying tension in the filament maintains connection of the sealing tip to the carrier tube, and releasing the tension in the filament permits release of the sealing tip within a channel formed in the bioadhesive material upon removal of the anchor through the bioadhesive material to seal the channel.
摘要翻译： 血管闭合系统包括载体管，可扩张锚，生物粘附材料，密封末端和细丝。 可膨胀锚固件安装到承载管并构造成延伸穿过容器穿刺以临时密封容器内的穿刺。 生物粘附材料设置在容器的外部并且构造成密封容器穿刺。 密封尖端安装在可伸缩锚的远端的载体管上。 灯丝与密封端连接并向近端延伸。 在灯丝中施加张力保持密封尖端与承载管的连接，并且释放细丝中的张力可以在将锚固件移除通过生物粘附材料以便密封通道时将密封尖端释放在形成于生物粘附材料中的通道内 。
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公开(公告)号：US20140222064A1
公开(公告)日：2014-08-07
申请号：US13757238
申请日：2013-02-01
发明人： Zachary J. Tegels
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00663 , A61B2017/00672 , A61B2017/0417 , A61B2017/0496
摘要： A vascular closure device includes a carrier tube and a sleeve. The carrier tube includes at least first and second lumens, the first lumen being configured to hold a sealing member, the second lumen being configured to provide blood flow from a distal opening thereof to a proximal opening thereof. The sleeve is positioned on the carrier tube and movable from a first position wherein blood flow through the second lumen is unobstructed, and a second position covering the distal and proximal openings to block blood flow through the second lumen.
摘要翻译： 血管闭合装置包括载体管和套管。 所述载体管包括至少第一和第二腔，所述第一腔构造成保持密封构件，所述第二腔构造成将血流从其远端开口提供到其近侧开口。 套筒定位在承载管上并且可以从第一位置移动，其中通过第二内腔的血液流动畅通无阻，而第二位置覆盖远侧和近侧开口以阻止血流通过第二腔。
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67.发明申请RAPID EXCHANGE TEMPORARY BLOOD FLOW CESSATION DEVICE FOR LARGE BORE CLOSURE 审中-公开快速交换临时血液流量消除装置，用于大型封闭公开(公告)号：US20140194918A1
公开(公告)日：2014-07-10
申请号：US13787204
申请日：2013-03-06
发明人： Zachary J. Tegels
CPC分类号： A61M29/00 , A61B17/0057 , A61B17/0469 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B2017/00663 , A61B2017/00867 , A61B2017/0472 , A61M29/02 , A61M2025/0183 , A61M2025/1052
摘要： A blood flow cessation device includes a catheter, an expandable member, and a rapid exchange port. The catheter includes a distal end portion and a proximal end portion. The expandable member is positioned at the distal end portion and is selectively expandable to stop blood flow through a vessel. The rapid exchange port is formed in the catheter at a location proximal of the expandable member. The rapid exchange port is configured receive a guidewire that passes through the distal end portion of the catheter to be positioned within the vessel.
摘要翻译： 血液流动停止装置包括导管，可扩张构件和快速交换口。 导管包括远端部分和近端部分。 可扩张构件位于远端部分并且可选择性地可扩张以阻止血液通过血管。 快速交换口形成在可扩张构件的近侧位置处的导管中。 快速交换口被构造成接收穿过导管的远端部分以定位在容器内的导丝。
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68.发明申请BIOADHESIVE MIXING AND PREPARATION SYSTEMS AND METHODS USING TWO SYRINGES 审中-公开生物混合和制备系统和使用两种注射剂的方法公开(公告)号：US20140135831A1
公开(公告)日：2014-05-15
申请号：US13779031
申请日：2013-02-27
发明人： Troy T. White , Zachary J. Tegels , Edward E. Parsonage , Russell D. Terwey , Martha Escobar , Timothy M. McGlinch , Bernhard Kaeferlein
IPC分类号： A61B17/00
CPC分类号： A61B17/00491 , A61B17/0057 , A61B2017/00495 , A61B2017/0065 , A61B2017/22067
摘要： A bioadhesive mixing assembly includes first and second syringes and an adapter. The first syringe includes first and second chambers holding a first sealant component and an activator, respectively. The second syringe includes third and fourth chambers holding a second sealant component and one of an activator or a third sealant component, respectively. The adapter is mounted to the first syringe and includes first and second channels in flow communication with the first and second chambers, a first seal member providing sealed access to the first and second channels, first and second needles connected in flow communication with the third and fourth chambers, and a second seal member enclosing the first and second needles. Connecting the adapter to the second syringe punctures the first and second seal members with the first and second syringes to create flow communication between the first and third chambers and the second and fourth chambers.
摘要翻译： 生物粘合剂混合组件包括第一和第二注射器和适配器。 第一注射器包括分别保持第一密封剂组分和活化剂的第一和第二腔室。 第二注射器包括分别保持第二密封剂组分和活化剂或第三密封剂组分之一的第三和第四室。 适配器安装到第一注射器并且包括与第一和第二腔室流体连通的第一和第二通道，第一密封构件，其提供对第一和第二通道的密封通路，与第三和第二腔室连通的第一和第二针头， 第四腔室和封闭第一和第二针头的第二密封构件。 将适配器连接到第二注射器用第一和第二注射器刺穿第一和第二密封构件，以在第一和第三腔室与第二和第四腔室之间产生流动连通。
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公开(公告)号：US20140135830A1
公开(公告)日：2014-05-15
申请号：US13778701
申请日：2013-02-27
发明人： Edward E. Parsonage , Martha Escobar , Zachary J. Tegels , Russell D. Terwey , Troy T. White , Bernhard Kaeferlein , Timothy M. McGlinch
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00495 , A61B2017/0065
摘要： A manifold for the delivery of bioadhesive sealant may comprise an inlet, a first outlet, a second outlet, and at least one valve positioned and configured to facilitate selective fluid communication between the inlet and the first outlet and the inlet and the second outlet. A syringe for delivering a bioadhesive sealant may comprise at least one barrel, at least one plunger, and at least one feature positioned and configured to prevent movement of the at least one plunger relative to the at least one barrel after a first predetermined quantity of bioadhesive sealant has been delivered. A bioadhesive sealant delivery system may comprise a manifold, a syringe, and a catheter, wherein a first lumen of the catheter is coupled to a first outlet of the manifold and a second lumen of the catheter coupled to a second outlet of the manifold.
摘要翻译： 用于输送生物粘附密封剂的歧管可以包括入口，第一出口，第二出口和至少一个阀，其定位和构造成促进入口与第一出口以及入口和第二出口之间的选择性流体连通。 用于递送生物粘合剂密封剂的注射器可以包括至少一个筒体，至少一个柱塞，以及至少一个特征定位和构造成在第一预定量的生物粘附剂之后防止至少一个柱塞相对于至少一个筒体移动 密封剂已经交付。 生物粘附密封剂输送系统可以包括歧管，注射器和导管，其中导管的第一内腔联接到歧管的第一出口，并且导管的第二腔联接到歧管的第二出口。
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70.发明申请公开(公告)号：US20140058429A1
公开(公告)日：2014-02-27
申请号：US13772933
申请日：2013-02-21
发明人： Zachary J. Tegels
CPC分类号： A61B17/3439 , A61B17/0057 , A61B17/3417 , A61B17/3431 , A61M29/00
摘要： A tissue puncture access assembly that includes a sheath and a dilator. The sheath is operable between an expanded position with a first maximum outer diameter, and a collapsed position with a second maximum outer diameter that is less than the first maximum outer diameter. The dilator is insertable through the sheath and has a leading end positionable distal of a distal end of the sheath. The sheath is operated into the collapsed position prior to and during insertion with the dilator into a tissue puncture. The sheath is operated into the expanded position once positioned in the tissue puncture.
摘要翻译： 包括护套和扩张器的组织穿刺进入组件。 护套可在具有第一最大外径的扩张位置和小于第一最大外径的第二最大外径的折叠位置之间操作。 扩张器可以通过护套插入，并且具有位于护套的远端的远端的前端。 在扩张器插入组织穿刺之前和期间，鞘被操作到折叠位置。 一旦定位在组织穿刺中，护套就进入扩张位置。
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