公开(公告)号：US20030203441A1

公开(公告)日：2003-10-30

申请号：US10165038

申请日：2001-10-19

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/705 ,  C07K14/47 ,  C07K14/4703 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030203435A1

公开(公告)日：2003-10-30

申请号：US10145092

申请日：2001-10-18

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/4703 ,  A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07K14/70578 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030203434A1

公开(公告)日：2003-10-30

申请号：US10145088

申请日：2001-10-18

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/4703 ,  A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026 ,  C12N2799/027

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030195345A1

公开(公告)日：2003-10-16

申请号：US10013922

申请日：2001-10-21

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C07H021/02 ,  C07H021/04

CPC classification number: G11B5/022 ,  C07K2317/24 ,  C07K2319/30 ,  H04B10/508

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030195333A1

公开(公告)日：2003-10-16

申请号：US09978194

申请日：2001-10-15

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: A61K038/17 ,  C07K014/435 ,  C07K016/40 ,  C12P021/02 ,  C12N005/06 ,  G01N033/53 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  C07K14/4702 ,  C07K14/4703 ,  C07K14/475 ,  C07K14/52 ,  C07K14/521 ,  C07K14/54 ,  C07K14/705 ,  C07K14/70503 ,  C07K14/70578 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N9/00 ,  C12N2799/026 ,  C12N2799/027 ,  G01N33/573 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/99 ,  G01N2800/042

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030194410A1

公开(公告)日：2003-10-16

申请号：US10145087

申请日：2001-10-18

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: A61K039/00 ,  C07H021/04 ,  C12N009/00 ,  C12P021/02 ,  C12N005/06 ,  C07K014/435

CPC classification number: C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030190701A1

公开(公告)日：2003-10-09

申请号：US10145124

申请日：2001-10-19

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/4703 ,  A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07K14/70578 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030186365A1

公开(公告)日：2003-10-02

申请号：US10145017

申请日：2001-10-19

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/705 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026 ,  C12N2799/027

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030185841A1

公开(公告)日：2003-10-02

申请号：US10165067

申请日：2001-10-19

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12N009/00 ,  A61K039/00 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06 ,  C07K014/435

CPC classification number: C07K14/47 ,  C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030180867A1

公开(公告)日：2003-09-25

申请号：US10145089

申请日：2001-10-19

Applicant: Genentech, Inc.

Inventor： Avi Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.