公开(公告)号：US06641541B1

公开(公告)日：2003-11-04

申请号：US09626361

申请日：2000-07-27

申请人： Eric G. Lovett ,  Robert J. Sweeney

发明人： Eric G. Lovett ,  Robert J. Sweeney

IPC分类号： A61B502

CPC分类号： H03H21/0043 ,  A61B5/04017 ,  A61B5/0428 ,  A61B5/7203 ,  A61N1/3956 ,  H03H17/026

摘要： A method and apparatus for implementing a signal morphology preservation smoothing scheme. The smoothing scheme includes generating an output signal representative of a filtered version of the input signal, wherein the output signal is generated by adaptively removing low amplitude, high frequency noise components while simultaneously preserving signal morphology of the input signal. The smoothing scheme includes comparison of a distance metric against a distance threshold to determine whether an initial smoothed version of the input signal would be oversmoothed or undersmoothed. Then the smoothing scheme appropriately increments, decrements, or maintains the initial level of smoothing to generate an optimal smoothed signal representative of the output signal.

摘要翻译： 一种实现信号形态保存平滑方案的方法和装置。 平滑方案包括产生表示输入信号的滤波版本的输出信号，其中通过自适应地去除低幅度高频噪声分量而产生输出信号，同时保持输入信号的信号形态。 平滑方案包括距离度量与距离阈值的比较，以确定输入信号的初始平滑版本是否将被过度平缓或不足够的。 然后平滑方案适当地增加，减少或维持平滑的初始水平，以产生表示输出信号的最佳平滑信号。

公开(公告)号：US06496731B1

公开(公告)日：2002-12-17

申请号：US09548981

申请日：2000-04-14

申请人： Eric G. Lovett

发明人： Eric G. Lovett

IPC分类号： A61N1365

CPC分类号： A61B5/046 ,  A61M5/142 ,  A61N1/3621

摘要： A cardiac rhythm management system including a highly sensitive technique for discriminating AF from AFL. An electrode disposed in or about a heart senses a cardiac signal. A controller through a sensing circuit receives the sensed cardiac signal from the electrode and processes the sensed cardiac signal to compute an average cycle length-to-cycle length variation based on serial interval relationships from the sensed cardiac signal, and then comparing the computed average cycle length-to-cycle length variation to one or more pre-determined threshold values to discriminate AF from AFL. As a result of substantial difference in cycle length-to-cycle length variation between AF and AFL (despite similar average cycle lengths), the sequence-based measure of cycle length-to-cycle length variability proves to be a highly specific and reliable discriminator of AF from AFL.

摘要翻译： 一种心律管理系统，包括用于区分AF与AFL的高灵敏度技术。 设置在心脏中或周围的电极检测心脏信号。 通过感测电路的控制器从电极接收感测到的心脏信号并处理感测的心脏信号，以基于来自感测的心脏信号的串行间隔关系计算平均周期长度与周期的长度变化，然后比较所计算的平均周期 长度到周期的长度变化到一个或多个预定阈值以区分AF与AFL。 由于AF和AFL之间的周期长度与周期长度变化有很大的差异（尽管类似的平均周期长度），基于序列的周期长度 - 周期长度变异性测量证明是一种高度特异性和可靠的鉴别器 AFL AF。

公开(公告)号：US06434417B1

公开(公告)日：2002-08-13

申请号：US09535872

申请日：2000-03-28

申请人： Eric G. Lovett

发明人： Eric G. Lovett

IPC分类号： A61B50452

CPC分类号： A61B5/04525 ,  A61B5/7239

摘要： A system and method for detection of specific cardiac depolarization events, such as atrial and ventricular beats. Cardiac electrical activity is sensed to generate a sense signal that is decomposed into components by orthogonal filters. Statistical features are extracted from the components and analyzed to detect a specific event. In one embodiment, the sense signal is decomposed into frequency components by bandpass filtering. The design of the bandpass filters is such that the frequency components can be analyzed to determine whether they match the frequency components of a template signal corresponding to the specific cardiac depolarization event.

摘要翻译： 用于检测特异性心脏去极化事件的系统和方法，例如心房和心室搏动。 感测心脏电活动以产生通过正交滤波器分解成分量的感测信号。 从组件中提取统计特征，并进行分析以检测特定事件。 在一个实施例中，通过带通滤波将感测信号分解成频率分量。 带通滤波器的设计使得可以分析频率分量以确定它们是否与对应于特定心脏去极化事件的模板信号的频率分量相匹配。