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    Quantitative methods for obtaining tissue characteristics from optical coherence tomography images
    42.
    发明申请
    Quantitative methods for obtaining tissue characteristics from optical coherence tomography images 审中-公开
    从光学相干断层扫描图像获得组织特征的定量方法

    公开(公告)号：US20090306520A1

    公开(公告)日：2009-12-10

    申请号：US12455523

    申请日：2009-06-02

    Applicant: Joseph M. Schmitt ,  Chenyang Xu

    Inventor： Joseph M. Schmitt ,  Chenyang Xu

    IPC: A61B6/00

    CPC classification number: A61B5/6852 ,  A61B5/0066 ,  A61B5/7264

    Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

    Abstract translation: 用于确定通过光学相干断层摄影（OCT）成像的组织或组织的性质的方法和装置。 在一个实施例中，测量OCT光束的后向散射和衰减，并且基于这些测量，并且针对对应于该部分的后向散射和衰减的特定值的图像的每个部分分配诸如颜色的标记。 然后用标记显示图像，然后用户可以确定组织特征。 在替代实施例中，通过给出反向散射和衰减值的组合的程序，组织特征被自动分类。

    Opto-acoustic imaging devices and methods
    43.
    发明申请
    Opto-acoustic imaging devices and methods 有权
    光声成像装置及方法

    公开(公告)号：US20080161696A1

    公开(公告)日：2008-07-03

    申请号：US11983417

    申请日：2007-11-08

    Applicant: Joseph M. Schmitt ,  Christopher Petersen ,  Toru Ohashi ,  Tetsuya Nakamatsu

    Inventor： Joseph M. Schmitt ,  Christopher Petersen ,  Toru Ohashi ,  Tetsuya Nakamatsu

    IPC: A61B8/00

    CPC classification number: A61B5/0066 ,  A61B5/0095 ,  A61B5/6852 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4461

    Abstract: In one aspect, the invention relates to a probe. The probe includes a sheath, a flexible, bi-directionally rotatable, optical subsystem positioned within the sheath, the optical subsystem comprising a transmission fiber, the optical subsystem capable of transmitting and collecting light of a predetermined range of wavelengths along a first beam having a predetermined beam size. The probe also includes an ultrasound subsystem, the ultrasound subsystem positioned within the sheath and adapted to propagate energy of a predetermined range of frequencies along a second beam having a second predetermined beam size, wherein a portion of the first and second beams overlap a region during a scan.

    Abstract translation: 一方面，本发明涉及一种探针。 探针包括位于护套内的护套，柔性双向可旋转的光学子系统，光学子系统包括传输光纤，该光学子系统能够沿着具有第一光束的第一光束发射和收集预定波长范围的光 预定的光束尺寸。 所述探针还包括超声子系统，所述超声子系统位于护套内并且适于沿具有第二预定光束尺寸的第二光束传播预定频率范围的能量，其中第一和第二光束的一部分在 扫描。

    STENT PLANNING SYSTEMS AND METHODS USING VESSEL REPRESENTATION
    44.
    发明申请
    STENT PLANNING SYSTEMS AND METHODS USING VESSEL REPRESENTATION 有权

    公开(公告)号：US20250143798A1

    公开(公告)日：2025-05-08

    申请号：US19017630

    申请日：2025-01-11

    Applicant: LightLab Imaging, Inc.

    Inventor： Ajay Gopinath

    IPC: A61B34/10 ,  A61B5/00 ,  A61B5/107 ,  A61B6/50 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/12 ,  A61B34/00 ,  A61F2/82 ,  G06N20/00 ,  G16H20/40 ,  G16H50/30 ,  G16H50/50

    Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

    Lumen morphology and vascular resistance measurements data collection systems apparatus and methods
    45.
    发明授权
    Lumen morphology and vascular resistance measurements data collection systems apparatus and methods 有权

    公开(公告)号：US12285240B2

    公开(公告)日：2025-04-29

    申请号：US17968927

    申请日：2022-10-19

    Applicant: LightLab Imaging, Inc.

    Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    IPC: A61B5/02 ,  A61B5/00

    Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

    Systems and methods for classification of arterial image regions and features thereof
    46.
    发明授权
    Systems and methods for classification of arterial image regions and features thereof 有权

    公开(公告)号：US12229966B2

    公开(公告)日：2025-02-18

    申请号：US18153148

    申请日：2023-01-11

    Applicant: LightLab Imaging, Inc.

    Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

    IPC: G06N3/08 ,  G06F18/211 ,  G06F18/214 ,  G06F18/40 ,  G06N3/04 ,  G06T7/11

    Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

    Intravascular measurement and data collections systems
    48.
    发明授权
    Intravascular measurement and data collections systems 有权

    公开(公告)号：US12178612B2

    公开(公告)日：2024-12-31

    申请号：US18367588

    申请日：2023-09-13

    Applicant: LightLab Imaging, Inc.

    Inventor： Joseph M. Schmitt ,  Chenyang Xu

    IPC: A61B5/00

    Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

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