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145 条记录 (耗时 0.039 秒)

    Prosthetic tissue valve
    44.
    发明授权
    Prosthetic tissue valve 有权

    公开(公告)号：US08409275B2

    公开(公告)日：2013-04-02

    申请号：US13560573

    申请日：2012-07-27

    申请人： Robert G. Matheny

    发明人： Robert G. Matheny

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412

    摘要： A prosthetic tissue valve for aortic, pulmonary, mitral or tricuspid valve replacement is described herein. A sewing ring for use with the prosthetic tissue valve is also described. The valve can have a circumference that is a predetermined distance larger than the circumference of an annulus in a defective valve. The valve can be substantially planar in an unstressed position before attachment at the annulus and substantially non-planar upon attachment in a biased position at the annulus. Methods are provided for placing the valve as described herein in the biased position within the annulus of the defective valve.

    Prosthetic tissue valve
    46.
    发明授权
    Prosthetic tissue valve 有权
    假肢组织瓣膜

    公开(公告)号：US08257434B2

    公开(公告)日：2012-09-04

    申请号：US12875727

    申请日：2010-09-03

    申请人： Robert G. Matheny

    发明人： Robert G. Matheny

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412

    摘要： A prosthetic tissue valve for aortic, pulmonary, mitral or tricuspid valve replacement is described herein. A sewing ring for use with the prosthetic tissue valve is also described. The valve can have a circumference that is a predetermined distance larger than the circumference of an annulus in a defective valve. The valve can be substantially planar in an unstressed position before attachment at the annulus and substantially non-planar upon attachment in a biased position at the annulus. Methods are provided for placing the valve as described herein in the biased position within the annulus of the defective valve.

    摘要翻译： 本文描述了用于主动脉，肺，二尖瓣或三尖瓣置换的假体组织瓣膜。 还描述了与假肢组织瓣一起使用的缝合环。 阀可以具有比缺陷阀中的环的圆周大的预定距离的圆周。 在连接到环形空间之前，阀可以在非受压位置处基本上是平面的，并且在环形偏压位置处附接时基本上不平面。 提供了用于将如本文所述的阀放置在有缺陷阀的环形空间内的偏置位置的方法。

    Compositions for reconstruction, replacement or repair of intracardiac tissue
    47.
    发明申请
    Compositions for reconstruction, replacement or repair of intracardiac tissue 审中-公开
    用于重建，置换或修复心内组织的组合

    公开(公告)号：US20070014869A1

    公开(公告)日：2007-01-18

    申请号：US11334631

    申请日：2006-01-18

    申请人： Robert Matheny

    发明人： Robert Matheny

    IPC分类号： A61K35/38 ,  A61K35/37

    CPC分类号： A61K48/00 ,  A61K9/0019 ,  A61L27/3633 ,  A61L27/367 ,  A61L27/3683 ,  A61L27/3873 ,  A61L2400/06 ,  A61L2430/20

    摘要： The invention is to a composition for reconstruction, replacement or repair of a defect in or dsmage to intracardiac tissue comprising a patch, emulsion, injectable solution or other composition comprising extracellular matrix. As extracellular matrix can assimilate with the intracardiac tissue to help generate healthy functioning tissue, using extracellular matrix to address a defect in intracardiac tissue can obviate the need for second or subsequent open heart surgeries, or if the composition can be delivered in a minimally invasive medical procedure, can obviate the need for open heart surgery altogether. Conduction of the intracardiac tissue may also be restored using extracellular matrix material to reconstruct, replace or repair the damaged intracardiac tissue.

    摘要翻译： 本发明涉及一种用于重组，置换或修复包括贴剂，乳剂，可注射溶液或包含细胞外基质的其它组合物在内的心脏内组织的损伤的组合物。 由于细胞外基质可以与心脏内组织同化以帮助产生健康的功能组织，所以使用细胞外基质来解决心内组织中的缺陷可以避免对第二次或随后的开放心脏手术的需要，或者如果组合物可以在微创医学中递送 程序，可以完全消除开心手术的需要。 也可以使用细胞外基质材料来恢复心脏内组织的传导，以重建，替换或修复损伤的心内组织。

    Systems, apparatus and methods for sealing perivalvular leaks
    49.
    发明授权
    Systems, apparatus and methods for sealing perivalvular leaks 有权

    公开(公告)号：US12029643B2

    公开(公告)日：2024-07-09

    申请号：US17231229

    申请日：2021-04-15

    申请人： CorMatrix Cardiovascular, Inc.

    发明人： Robert G Matheny

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2/2463 ,  A61F2250/0069

    摘要： A biocompatible and biodegradable construct comprising a base expandable member and an outer coating comprising poly(glycerol sebacate) (PGS), the base expandable member comprising acellular extracellular matrix (ECM) derived from a mammalian tissue source, the acellular ECM exhibiting a flexible, porous, expandable structure, which is adapted to expand upon exposure to and absorption of a bodily fluid, wherein the construct seals a perivalvular leak when disposed proximate thereto.