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41.
公开(公告)号:US11232541B2
公开(公告)日:2022-01-25
申请号:US16594567
申请日:2019-10-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Chenyu You , Wenxiang Cong , Hongming Shan , Guang Li
Abstract: A system for generating a high resolution (HR) computed tomography (CT) image from a low resolution (LR) CT image is described. The system includes a first generative adversarial network (GAN) and a second GAN. The first GAN includes a first generative neural network (G) configured to receive a training LR image dataset and to generate a corresponding estimated HR image dataset, and a first discriminative neural network (DY) configured to compare a training HR image dataset and the estimated HR image dataset. The second GAN includes a second generative neural network (F) configured to receive the training HR image dataset and to generate a corresponding estimated LR image dataset, and a second discriminative neural network (DX) configured to compare the training LR image dataset and the estimated LR image dataset. The system further includes an optimization module configured to determine an optimization function based, at least in part, on at least one of the estimated HR image dataset and/or the estimated LR image dataset. The optimization function contains at least one loss function. The optimization module is further configured to adjust a plurality of neural network parameters associated with at least one of the first GAN and/or the second GAN, to optimize the optimization function.
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公开(公告)号:US20210389399A1
公开(公告)日:2021-12-16
申请号:US17279400
申请日:2019-03-13
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Lars Arne Gjesteby , Wenxiang Cong
Abstract: A simultaneous emission-transmission tomography in an MRI hardware framework is described. A method of multimodality imaging includes reconstructing, by a simultaneous emission transmission (SET) circuitry, a concentration image based, at least in part, on a plurality of selected γ-rays; and reconstructing, by the SET circuitry, an attenuation image based, at least in part, on the plurality of selected γ-rays. The plurality of selected γ-rays is emitted by a polarized radio tracer included in a test object. The selected γ-rays are selected based, at least in part, on a radio frequency (RF) pulse and based, at least in part, on a gradient magnetic field.
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43.
公开(公告)号:US11127175B2
公开(公告)日:2021-09-21
申请号:US16647220
申请日:2018-09-26
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
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公开(公告)号:US20210209819A1
公开(公告)日:2021-07-08
申请号:US17194946
申请日:2021-03-08
Applicant: University of Iowa Research Foundation , Shandong University , Shandong Provincial Chest Hospital , Rensselaer Polytechnic Institute
Inventor: Wenxiang Cong , Ye Yangbo , Ge Wang , Shuwei Mao , Yingmei Wang
Abstract: The disclosed apparatus, systems and methods relate to a framelet-based iterative algorithm for polychromatic CT which can reconstruct two components using a single scan. The algorithm can have various steps including a scaled-gradient descent step of constant or variant step sizes; a non-negativity step; a soft thresholding step; and a color reconstruction step.
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公开(公告)号:US11020077B2
公开(公告)日:2021-06-01
申请号:US15759326
申请日:2016-09-14
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Yan Xi , Wenxiang Cong , Jun Zhao
Abstract: Novel and advantageous systems and method for obtaining and/or reconstructing simultaneous computed tomography (CT)-magnetic resonance imaging (MRI) images are provided. Structural coupling (SC) and compressive sensing (CS) techniques can be combined to unify and improve CT and MRI reconstruction. A bidirectional image estimation method can be used to connect images from different modalities, with CT and MRI data serving as prior knowledge to each other to produce better CT and MRI image quality than would be realized with individual reconstruction.
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公开(公告)号:US10970887B2
公开(公告)日:2021-04-06
申请号:US16312704
申请日:2017-06-26
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong , Qingsong Yang
Abstract: Tomographic/tomosynthetic image reconstruction systems and methods in the framework of machine learning, such as deep learning, are provided. A machine learning algorithm can be used to obtain an improved tomographic image from raw data, processed data, or a preliminarily reconstructed intermediate image for biomedical imaging or any other imaging purpose. In certain cases, a single, conventional, non-deep-learning algorithm can be used on raw imaging data to obtain an initial image, and then a deep learning algorithm can be used on the initial image to obtain a final reconstructed image. All machine learning methods and systems for tomographic image reconstruction are covered, except for use of a single shallow network (three layers or less) for image reconstruction.
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公开(公告)号:US10722201B2
公开(公告)日:2020-07-28
申请号:US15741047
申请日:2016-07-27
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Wenxiang Cong
Abstract: Novel and advantageous systems and methods for performing X-ray imaging by using an X-ray source with source grating functionality incorporated therein are provided. An electron beam can be electromagnetically manipulated such that the X-ray source emits radiation in a pattern that is the same as if the radiation had already passed through a source grating.
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公开(公告)号:US20190332928A1
公开(公告)日:2019-10-31
申请号:US16394111
申请日:2019-04-25
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Wenxiang Cong , Fenglei Fan
Abstract: A second order neuron for machine learning is described. The second order neuron includes a first dot product circuitry and a second dot product circuitry. The first dot product circuitry is configured to determine a first dot product of an intermediate vector and an input vector. The intermediate vector corresponds to a product of the input vector and a first weight vector or the input vector and a weight matrix. The second dot product circuitry is configured to determine a second dot product of the input vector and a second weight vector. The input vector, the intermediate vector, the first weight vector and the second weight vector each contain a number, n, elements.
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公开(公告)号:US20170360385A1
公开(公告)日:2017-12-21
申请号:US15538376
申请日:2015-12-22
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Yan Xi , Wenxiang Cong , Zaifeng Shi
CPC classification number: A61B6/4233 , A61B6/032 , A61B6/4241 , A61B6/4266 , A61B6/4275 , A61B6/4291 , A61B6/482 , A61B6/5205 , A61B6/5217 , G01T1/2985
Abstract: Novel and advantageous methods and systems for performing spectral computed tomography are provided. An edge-on detector, such as a silicon strip detector, can be used to receive X-rays after passing through a sample to be imaged. An energy resolving process can be performed on the collected X-ray radiation. The CT scanner can have third-generation or fourth-generation geometry.
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公开(公告)号:US20170000438A1
公开(公告)日:2017-01-05
申请号:US14789585
申请日:2015-07-01
Applicant: GENERAL ELECTRIC COMPANY , RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Robert John Filkins , Ahmad Nadeem Ishaque , Alok Mani Srivastava , Peter William Lorraine , Holly Ann Camanzo , Xiaolei Shi , Vasile Bogdan Neculaes , Sam Joseph Camardello , Gregory Boverman , Ge Wang , Wenxiang Cong
CPC classification number: A61B6/481 , A61B6/02 , A61B6/4258 , A61B6/485 , A61B8/0808 , A61B8/481 , A61K49/0015 , A61K49/0065
Abstract: The present approach generally relates to systems and methods for implementing energy modulated tomographic imaging of nanoparticles. In certain embodiments, a first energy is used to activate probe particles labeling an anatomy or tissue of interest. The probe particles, once activated, emit photons at a different rate and/or spectrum in response to an underlying physiological event, such as action potentials propagating in the labeled anatomy or tissue. The emitted photons may then be detected and used to map or image the occurrence of the physiological event.
Abstract translation: 本方法通常涉及用于实现纳米颗粒的能量调制层析成像的系统和方法。 在某些实施方案中,使用第一能量来激活标记感兴趣的解剖结构或组织的探针颗粒。 一旦被激活,探针颗粒响应于潜在的生理事件(例如在标记的解剖结构或组织中传播的动作电位)以不同的速率和/或光谱发射光子。 然后可以检测发射的光子并用于映射或成像生理事件的发生。
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