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    DRY POWDER DRUG DELIVERY SYSTEM AND METHODS
    43.
    发明申请
    DRY POWDER DRUG DELIVERY SYSTEM AND METHODS 有权
    干粉药物输送系统及方法

    公开(公告)号：US20140014106A1

    公开(公告)日：2014-01-16

    申请号：US13941365

    申请日：2013-07-12

    Applicant: Mannkind Corporation

    Inventor： Chad C. Smutney ,  Benoit Adamo ,  Brendan F. Laurenzi ,  P. Spencer Kinsey

    IPC: A61M15/00

    CPC classification number: A61M15/00 ,  A61M11/001 ,  A61M15/0005 ,  A61M15/002 ,  A61M15/0021 ,  A61M15/0025 ,  A61M15/0028 ,  A61M15/0065 ,  A61M2016/0027 ,  A61M2202/064 ,  A61M2205/076 ,  A61M2206/14 ,  A61M2206/16 ,  A61M2206/20

    Abstract: A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.

    Abstract translation: 公开了一种肺部药物递送系统，其包括具有或不具有用于递送干粉制剂的药筒的呼吸驱动的干粉吸入器。 吸入器和药筒可以设置有药物递送制剂，其包含例如二酮哌嗪和活性成分，包括小有机分子，肽和蛋白质，包括激素例如胰岛素和胰高血糖素样肽1，用于治疗 疾病和病症，例如疾病和病症，包括诸如糖尿病和/或肥胖的内分泌疾病。

    APPARATUS, SYSTEM AND METHOD FOR DETECTING AND MONITORING INHALATIONS
    45.
    发明申请
    APPARATUS, SYSTEM AND METHOD FOR DETECTING AND MONITORING INHALATIONS 有权

    公开(公告)号：US20210361888A1

    公开(公告)日：2021-11-25

    申请号：US17077712

    申请日：2019-04-24

    Applicant: Mannkind Corporation

    Inventor： John J. Pocreva, III ,  Benoit Adamo ,  Brendan Laurenzi ,  Chad C Smutney ,  P. Spencer Kinsey

    IPC: A61M15/00 ,  G09B5/02 ,  G09B23/28 ,  A61K38/28 ,  A61K47/22

    Abstract: Described herein are an interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The inhaler device can be used in a wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system concurrently as the inhalation is performed and thus the subject's inhalation can be evaluated as well as the performance of the inhalation system. The system can also detect the identity of the medicament, its dosage, lot, expiration, etc. and the characteristic profile of a dry powder formulation emitted from the inhalation system in use and allows effective delivery of powder doses. Data obtained can be transmitted to a digital application and can be analyzed for optimal therapeutic utility.

    DRY POWDER DRUG DELIVERY SYSTEM AND METHODS
    46.
    发明申请
    DRY POWDER DRUG DELIVERY SYSTEM AND METHODS 审中-公开

    公开(公告)号：US20200338283A1

    公开(公告)日：2020-10-29

    申请号：US16924067

    申请日：2020-07-08

    Applicant: MannKind Corporation

    Inventor： Chad C. Smutney ,  Benoit Adamo ,  Brendan F. Laurenzi ,  P. Spencer Kinsey

    IPC: A61M15/00 ,  A61M11/00

    Abstract: A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.

    Dry powder drug delivery system and methods
    47.
    发明授权
    Dry powder drug delivery system and methods 有权

    公开(公告)号：US10744280B2

    公开(公告)日：2020-08-18

    申请号：US15706504

    申请日：2017-09-15

    Applicant: MannKind Corporation

    Inventor： Chad C. Smutney ,  Benoit Adamo ,  Brendan F. Laurenzi ,  P. Spencer Kinsey

    IPC: A61M15/00 ,  A61M11/00 ,  A61M16/00

    Abstract: A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.

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