公开(公告)号：US20220117551A1

公开(公告)日：2022-04-21

申请号：US17519764

申请日：2021-11-05

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B5/00 ,  A61B5/107 ,  A61B5/02 ,  A61B5/0215 ,  A61B5/026

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for pre-stent planning, stent planning and post-stent planning using one or more computing devices. In one embodiment, a method generates one or more stent profiles, such as a target stent profile, that are user configurable during a pre-stent planning stage by selecting one or more frames. The method performs a comparative analysis of the previously set target stent profile relative to a vessel lumen region post stent deployment. The method and related user interfaces can alert a user to move, remove, reposition, or inflate a stent. The location of jailed side branches can also be identified and displayed based upon the comparative analysis. Parameters that change based on the outcome of the stent deployment can be displayed in terms of the predicted parameter value and the value that is measured or determined after stent deployment.

公开(公告)号：US11166668B2

公开(公告)日：2021-11-09

申请号：US14808901

申请日：2015-07-24

Applicant: LIGHTLAB IMAGING, INC.

Inventor： Ajay Gopinath

IPC: A61B5/00 ,  A61B5/107 ,  A61B5/02 ,  A61B5/026 ,  A61F2/95 ,  A61B5/0215 ,  A61F2/82

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for pre-stent planning, stent planning and post-stent planning using one or more computing devices. In one embodiment, a method generates one or more stent profiles, such as a target stent profile, that are user configurable during a pre-stent planning stage by selecting one or more frames. The method performs a comparative analysis of the previously set target stent profile relative to a vessel lumen region post stent deployment. The method and related user interfaces can alert a user to move, remove, reposition, or inflate a stent. The location of jailed side branches can also be identified and displayed based upon the comparative analysis. Parameters that change based on the outcome of the stent deployment can be displayed in terms of the predicted parameter value and the value that is measured or determined after stent deployment.

公开(公告)号：US10593037B2

公开(公告)日：2020-03-17

申请号：US15488005

申请日：2017-04-14

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: G06T7/00 ,  G06T7/11 ,  G06T7/13 ,  A61B5/00 ,  A61B5/02 ,  G06T5/00

Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.

公开(公告)号：US20180085170A1

公开(公告)日：2018-03-29

申请号：US15718835

申请日：2017-09-28

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B34/10

CPC classification number: A61B34/10 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/107 ,  A61B6/504 ,  A61B8/06 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/463 ,  A61B8/466 ,  A61B8/5223 ,  A61B34/25 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/82 ,  A61F2240/001 ,  G06N20/00 ,  G16H20/40 ,  G16H50/30 ,  G16H50/50

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

公开(公告)号：US20250143798A1

公开(公告)日：2025-05-08

申请号：US19017630

申请日：2025-01-11

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B34/10 ,  A61B5/00 ,  A61B5/107 ,  A61B6/50 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/12 ,  A61B34/00 ,  A61F2/82 ,  G06N20/00 ,  G16H20/40 ,  G16H50/30 ,  G16H50/50

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

公开(公告)号：US12229966B2

公开(公告)日：2025-02-18

申请号：US18153148

申请日：2023-01-11

Applicant: LightLab Imaging, Inc.

Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

IPC: G06N3/08 ,  G06F18/211 ,  G06F18/214 ,  G06F18/40 ,  G06N3/04 ,  G06T7/11

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

公开(公告)号：US12229961B2

公开(公告)日：2025-02-18

申请号：US17858468

申请日：2022-07-06

Applicant: LightLab Imaging, Inc.

Inventor： Gregory Patrick Amis ,  Ajay Gopinath ,  Mark Hoeveler

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/02 ,  G06T7/38 ,  G06T11/00 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50

Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.

公开(公告)号：US20240130793A1

公开(公告)日：2024-04-25

申请号：US18531971

申请日：2023-12-07

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B34/10 ,  A61B5/00 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/12 ,  G16H50/30 ,  G16H50/50

CPC classification number: A61B34/10 ,  A61B5/0084 ,  A61B8/06 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/463 ,  A61B8/466 ,  A61B8/5223 ,  G16H50/30 ,  G16H50/50 ,  A61B5/0066 ,  A61B6/504

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

公开(公告)号：US11741613B2

公开(公告)日：2023-08-29

申请号：US17561018

申请日：2021-12-23

Applicant: LightLab Imaging, Inc.

Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

IPC: G06N3/08 ,  G06T7/11 ,  G06N3/04 ,  G06F18/214 ,  G06F18/40 ,  G06F18/211

CPC classification number: G06T7/11 ,  G06F18/211 ,  G06F18/214 ,  G06F18/40 ,  G06N3/04 ,  G06N3/08 ,  G06V2201/03

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

公开(公告)号：US20230054891A1

公开(公告)日：2023-02-23

申请号：US17890672

申请日：2022-08-18

Applicant: LightLab Imaging, Inc.

Inventor： Wei Chiu ,  Shimin Li ,  Ajay Gopinath ,  Jacob Segev ,  Lorina Dascal

IPC: A61B5/02 ,  G16H30/20

Abstract: Systems and methods are disclosed for identifying features of a blood vessel using extravascular and intravascular images in order to estimate a virtual flow reserve (VFR) of the imaged blood vessel. Aspects of the disclosure include using extravascular images to estimate the size of the blood vessel in regions that have not been intravascularly imaged. The VFR estimation may be based on a resistance model that incorporates both the intravascular image data and the estimated blood vessel size. In other aspects, multiangled extravascular images are captured and analyzed in order to identify the size and orientation of branch vessels.