公开(公告)号：US10575804B2

公开(公告)日：2020-03-03

申请号：US15144425

申请日：2016-05-02

Applicant: Hologic, Inc.

Inventor： Andrew P. Smith ,  Jay A. Stein ,  Ken Defreitas ,  Ian Shaw ,  Zhenxue Jing ,  Loren Niklason ,  Baorui Ren ,  Christopher Ruth

IPC: A61B6/04 ,  A61B6/00 ,  A61B6/02 ,  A61B6/03

Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.

公开(公告)号：US10413255B2

公开(公告)日：2019-09-17

申请号：US15342038

申请日：2016-11-02

Applicant: Hologic, Inc.

Inventor： Jay Stein ,  Andrew P. Smith ,  Zhenxue Jing ,  Loren Niklason

IPC: A61B6/02 ,  A61B6/00 ,  G01N23/046 ,  A61B8/08

Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.

公开(公告)号：US10098601B2

公开(公告)日：2018-10-16

申请号：US15597713

申请日：2017-05-17

Applicant: Hologic, Inc.

Inventor： Andrew P. Smith ,  Jay A. Stein ,  Ken Defeitas ,  Ian Shaw ,  Zhenxue Jing ,  Lauren Niklason ,  Baouri Ren ,  Christopher Ruth

IPC: A61B6/04 ,  A61B6/00 ,  A61B6/02 ,  G06T11/00 ,  A61B6/10

Abstract: Systems and methods for breast x-ray tomosynthesis that enhance spatial resolution in the direction in which the breast is flattened for examination. In addition to x-ray data acquisition of 2D projection tomosynthesis images ETp1 over a shorter source trajectory similar to known breast tomosynthesis, supplemental 2D images ETp2 are taken over a longer source trajectory and the two sets of projection images are processed into breast slice images ETr that exhibit enhanced spatial resolution, including in the thickness direction of the breast. Additional features include breast CT of an upright patient's flattened breast, multi-mode tomosynthesis, and shielding the patient from moving equipment.

公开(公告)号：US20170135650A1

公开(公告)日：2017-05-18

申请号：US15342038

申请日：2016-11-02

Applicant: Hologic, Inc.

Inventor： Jay Stein ,  Andrew P. Smith ,  Zhenxue Jing ,  Loren Niklason

IPC: A61B6/02 ,  A61B8/08 ,  A61B6/00

CPC classification number: A61B6/025 ,  A61B6/405 ,  A61B6/4417 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B6/542 ,  G01N23/046

Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.

公开(公告)号：US09502148B2

公开(公告)日：2016-11-22

申请号：US14966011

申请日：2015-12-11

Applicant: Hologic, Inc.

Inventor： Baorui Ren ,  Andrew P. Smith ,  Thomas Farbizio ,  Zhenxue Jing ,  Jay Stein

IPC: G21K1/04 ,  G21K1/02 ,  A61B6/03 ,  A61B6/06 ,  A61B6/00 ,  A61B6/02

CPC classification number: A61B6/06 ,  A61B6/025 ,  A61B6/03 ,  A61B6/035 ,  A61B6/502 ,  G21K1/02 ,  G21K1/04

Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.

公开(公告)号：US20160270742A9

公开(公告)日：2016-09-22

申请号：US14057061

申请日：2013-10-18

Applicant: Hologic, Inc.

Inventor： Jay Stein ,  Andrew P. Smith ,  Zhenxue Jing ,  Loren Niklason

IPC: A61B6/02

CPC classification number: A61B6/025 ,  A61B6/405 ,  A61B6/4417 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B6/542 ,  A61B8/0825 ,  G01N23/046

Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.

公开(公告)号：US20160106383A1

公开(公告)日：2016-04-21

申请号：US14966011

申请日：2015-12-11

Applicant: Hologic, Inc.

Inventor： Baorui Ren ,  Andrew P. Smith ,  Thomas Farbizio ,  Zhenxue Jing ,  Jay Stein

IPC: A61B6/02 ,  A61B6/00 ,  A61B6/06

CPC classification number: A61B6/06 ,  A61B6/025 ,  A61B6/03 ,  A61B6/035 ,  A61B6/502 ,  G21K1/02 ,  G21K1/04

Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.

Abstract translation: 在断层合成系统中，静态焦点沿着与X射线源的定向运动相反并且大体上与X射线源的定向运动相同的方向移动，并且与静态焦点的移动同步地在每次曝光期间移动X射线准直器叶片。 静态焦点，X射线管和准直器刀片的同步运动有助于在曝光的整个持续时间内将有效焦斑保持在相对于乳房，检测器或两者的空间中，并将X射线场保持在检测器 和乳房静电。 移位准直器刀片遵循断层扫描合成扫描的多次X射线曝光的振荡模式。

公开(公告)号：US09226721B2

公开(公告)日：2016-01-05

申请号：US14319170

申请日：2014-06-30

Applicant: Hologic, Inc.

Inventor： Baorui Ren ,  Andrew P. Smith ,  Thomas Farbizio ,  Zhenxue Jing ,  Jay Stein

IPC: G21K1/04 ,  A61B6/03 ,  A61B6/06 ,  A61B6/00

CPC classification number: A61B6/06 ,  A61B6/025 ,  A61B6/03 ,  A61B6/035 ,  A61B6/502 ,  G21K1/02 ,  G21K1/04

Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.

公开(公告)号：US20150327826A1

公开(公告)日：2015-11-19

申请号：US14695090

申请日：2015-04-24

Applicant: Hologic, Inc.

Inventor： Andrew P. Smith ,  Jay A. Stein ,  Zhenxue Jing ,  Baorui Ren ,  Loren Niklason ,  Christopher Ruth ,  Ian Shaw

IPC: A61B6/00 ,  A61M5/00 ,  A61B10/04 ,  A61B6/02

CPC classification number: A61B6/025 ,  A61B6/12 ,  A61B6/4035 ,  A61B6/4417 ,  A61B6/463 ,  A61B6/466 ,  A61B6/481 ,  A61B6/482 ,  A61B6/502 ,  A61B6/5235 ,  A61B10/04 ,  A61M5/007 ,  F04C2270/041

Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.

Abstract translation: 双能量，单能量，乳房X射线摄影和断层合成模式的X射线成像的X射线成像系统和方法，有助于筛查和诊断乳房异常，特别是以血管异常为特征的乳房异常。

公开(公告)号：US20140314198A1

公开(公告)日：2014-10-23

申请号：US14319170

申请日：2014-06-30

Applicant: Hologic, Inc.

Inventor： Baorui Ren ,  Andrew P. Smith ,  Thomas Farbizio ,  Zhenxue Jing ,  Jay Stein

IPC: A61B6/06 ,  A61B6/00 ,  A61B6/03

CPC classification number: A61B6/06 ,  A61B6/025 ,  A61B6/03 ,  A61B6/035 ,  A61B6/502 ,  G21K1/02 ,  G21K1/04

Abstract: In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan.

Abstract translation: 在断层合成系统中，静态焦点沿着与X射线源的定向运动相反并且大体上与X射线源的定向运动相同的方向移动，并且与静态焦点的移动同步地在每次曝光期间移动X射线准直器叶片。 静态焦点，X射线管和准直器刀片的同步运动有助于在曝光的整个持续时间内将有效焦斑保持在相对于乳房，检测器或两者的空间中，并将x射线场保持在检测器上 和乳房静电。 移位准直器刀片遵循断层扫描合成扫描的多次X射线曝光的振荡模式。