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    Implantable medical devices fabricated from polymer blends with star-block copolymers
    35.
    发明授权
    Implantable medical devices fabricated from polymer blends with star-block copolymers 有权
    由具有星形嵌段共聚物的聚合物共混物制成的可植入医疗器械

    公开(公告)号：US08262723B2

    公开(公告)日：2012-09-11

    申请号：US11784925

    申请日：2007-04-09

    申请人： Yunbing Wang ,  David C. Gale ,  Bin Huang

    发明人： Yunbing Wang ,  David C. Gale ,  Bin Huang

    IPC分类号： A61F2/82

    CPC分类号： A61L27/48 ,  A61F2/91 ,  A61F2210/0004 ,  A61L27/58 ,  A61L31/041 ,  A61L31/148

    摘要： Implantable medical devices are fabricated from polymer blends with star-block copolymers. The polymer blends include a biodegradable matrix polymer blended with a biodegradable star-block copolymer. The copolymer has at least three arms and the arms include inner segments and outer segments. The inner segments form a discrete phase within a continuous phase, the continuous phase including the matrix polymer and the outer segments. The segments can include units having acidic degradation products that enhance the degradation rate of the blend.

    摘要翻译： 可植入医疗器械由具有星形嵌段共聚物的聚合物共混物制成。 聚合物共混物包括与可生物降解的星形嵌段共聚物共混的可生物降解的基质聚合物。 共聚物具有至少三个臂，并且臂包括内部段和外部段。 内部段在连续相中形成离散相，连续相包括基质聚合物和外部链段。 这些链段可以包括具有增强共混物降解速率的酸性降解产物的单元。

    Degradable polymeric implantable medical devices with continuous phase and discrete phase
    38.
    发明授权
    Degradable polymeric implantable medical devices with continuous phase and discrete phase 有权
    具有连续相和离散相的可降解聚合物可植入医疗器械

    公开(公告)号：US07923022B2

    公开(公告)日：2011-04-12

    申请号：US11521271

    申请日：2006-09-13

    申请人： Yunbing Wang ,  David C. Gale

    发明人： Yunbing Wang ,  David C. Gale

    IPC分类号： A61F2/02 ,  A61F2/00

    CPC分类号： A61L31/129 ,  A61L31/148

    摘要： An implantable medical device is disclosed comprising: a structural element, wherein the structural element includes: a continuous phase comprising a first polymer of LPLG; a discrete phase within the continuous phase, wherein the discrete phase comprises a second polymer including rapidly eroding elastic discrete phase segments. The second polymer further includes anchor segments that have the same or substantially the same chemical make up as the first polymer of the continuous phase, and at least some of the anchor segments have partially or completely phase-separated from the discrete phase into the continuous phase.

    摘要翻译： 公开了一种植入式医疗装置，包括：结构元件，其中所述结构元件包括：包含LPLG的第一聚合物的连续相; 连续相内的离散相，其中离散相包括第二聚合物，其包括快速侵蚀的弹性离散相段。 第二聚合物还包括具有与连续相的第一聚合物相同或基本上相同的化学构成的锚段，并且至少一些锚定段具有部分或完全相离离离相的连续相 。