Drug Delivery Device
    31.
    发明申请

    公开(公告)号:US20170151392A1

    公开(公告)日:2017-06-01

    申请号:US15321919

    申请日:2015-07-01

    申请人: Sanofi

    IPC分类号: A61M5/315 A61M5/20

    摘要: The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising a clicker arrangement. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) coupled to the dose selector (80) and arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10), a clutch (120) arranged between the number sleeve (60) and the drive sleeve (40), and a dispense clicker comprising a flexible arm (123) and a toothed profile (75). The device further comprises a button (70) operable to effect dose dispensing. The clutch comprises a separate clutch element (120) which is permanently rotationally constrained to the number sleeve (60). The flexible arm (123) is provided on the clutch element (120) and the toothed profile (75) is provided on the button (70).

    Data collection device for attachment to an injection device

    公开(公告)号:US11278677B2

    公开(公告)日:2022-03-22

    申请号:US16806810

    申请日:2020-03-02

    摘要: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.

    Injection device
    34.
    发明授权

    公开(公告)号:US10850043B2

    公开(公告)日:2020-12-01

    申请号:US16017794

    申请日:2018-06-25

    申请人: Sanofi

    摘要: The disclosure refers to a handheld injection device comprising a housing, a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing, a gauge element, which is at least partly interposed between the housing and the dose indicator, wherein the gauge element is axially guided within the housing and in threaded engagement with the dose indicator such that rotation of the dose indicator causes an axial displacement of the gauge element (80; 490). A contrast element having a first marking is provided and at least a region of the gauge element is provided with a second marking, with the first marking and/or the second marking being visible through a first window or aperture in the housing depending on the axial position of the gauge element within the housing.

    Drug injection device with resettable mechanism allowing piston rod retraction upon drug cartridge change

    公开(公告)号:US10596326B2

    公开(公告)日:2020-03-24

    申请号:US15517863

    申请日:2015-10-09

    申请人: Sanofi

    摘要: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a dose setting element rotatable relative to the housing during dose setting and dose dispensing, a drive member coupled to the dose setting member via a clutch, and a piston rod coupled to the housing and to the drive member Further, the device further comprises a cartridge holder removably attached to the housing and a reset element, which is permanently rotationally constrained to the housing and rotationally constrained to the drive member during dose setting, and at least one spring acting on the reset element, such that, if the cartridge holder is detached from the housing, the reset element is axially moved relative to the housing into a position in which the drive member is allowed to rotate relative to the housing.

    Dispense mechanism for a drug delivery device and drug delivery device

    公开(公告)号:US10525205B2

    公开(公告)日:2020-01-07

    申请号:US15313900

    申请日:2015-05-27

    摘要: A dispense mechanism for a drug delivery device for the delivery of a primary medicament in a primary cartridge and a secondary medicament in a secondary cartridge includes a primary drive member and a secondary drive member serve for driving a primary and a secondary lead screw. The primary drive member and the secondary drive member are configured to rotate during dose dispense. A coupling member serves for rotationally coupling the primary drive member to the secondary drive member and moves from a first position in which the primary drive member is rotationally decoupled from the secondary drive member into a second position in which the primary drive member is rotationally coupled to the secondary drive member during dose dispense. Rotation of the primary drive member moves the coupling member from the first position into the second position.

    Drug delivery device
    37.
    发明授权

    公开(公告)号:US10426890B2

    公开(公告)日:2019-10-01

    申请号:US15310188

    申请日:2015-05-27

    IPC分类号: A61M5/19 A61M5/24 A61M5/315

    摘要: The invention is directed to drug delivery device comprising a primary drug delivery assembly (3) with a primary dose dial sleeve (17) and a secondary drug delivery assembly (4) with a secondary drive sleeve (24). For user selection, a selection switch (48) is movable between a first, a second and a third position and a clutch (49) is connected to the selection switch (48) such that movement of the selection switch (48) causes rotation of the clutch (49). A secondary drive sleeve (24) is configured to rotate and to engage the clutch (49), wherein the clutch (49) is configured to transfer rotation to the secondary drive sleeve (24) when the selection switch (48) is moved from the first position into the second position and to disengage from the secondary drive sleeve (24) when the selection switch (48) is moved from the first into the third position.

    Injection device and assembly method

    公开(公告)号:US10201662B2

    公开(公告)日:2019-02-12

    申请号:US14782667

    申请日:2014-04-08

    申请人: Sanofi

    IPC分类号: A61M5/00 A61M5/315 A61M5/31

    摘要: An injection device includes a housing containing a cartridge containing a medicament and a movable bung. The housing includes an inner thread. The injection device includes a piston rod for moving the bung during dose dispensing. The piston rod includes an outer thread engaging the inner thread of the housing a bearing at its end facing the bung. The injection device further includes a driver coupled to the piston rod for driving the piston rod during dose dispensing. In the unused delivery state of the device, the bearing abuts the bung. The invention further refers to an assembly method for such an injection device.