公开(公告)号：US09963690B2

公开(公告)日：2018-05-08

申请号：US14787422

申请日：2014-04-29

申请人： NOVOZYMES A/S

发明人： Jesper Vind ,  Santhosh Mepadam Vasu ,  Rakhi Saikia ,  Aditya Basu

IPC分类号： C12P7/06 ,  C12N9/34 ,  C12N9/26 ,  C12P19/02 ,  C12P19/20

CPC分类号： C12N9/2428 ,  C12N9/2408 ,  C12P19/02 ,  C12P19/20 ,  C12Y302/01003

摘要： The present invention relates to glucoamylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20170137795A1

公开(公告)日：2017-05-18

申请号：US15310247

申请日：2015-05-26

申请人： Novozymes A/S

发明人： Allan Svendsen ,  Rakhi Saikia ,  Sohel Dalal ,  Vikram Kjoeller Bhatia ,  Lone Baunsgaard

IPC分类号： C12N9/20

CPC分类号： C12N9/20 ,  C12Y301/01003

摘要： The invention relates to a method for generating a preparation of lipase with increased lipolytic activity comprising a step of altering one or more nucleotides in a polynucleotide comprising a first polynucleotide encoding a propeptide operationally linked to a second polynucleotide encoding a lipase, wherein the alteration of one or more nucleotides are made in the first polynucleotide and the alteration independently results in a substitution, an insertion or a deletion in the encoded propeptide amino acid sequence