摘要:
The present invention relates to the preparation of insulinotropic peptides that are synthesized using a solid and solution phase (“hybrid”) approach. Generally, the approach includes synthesizing three different peptide intermediate fragments using solid phase chemistry. Solution phase chemistry is then used to add additional amino acid material to one of the fragments. The fragments are then coupled together in the solid solution phase. The use of a pseudoproline in one of the fragments eases solid phase synthesis of that fragment and also eases subsequent solution phase coupling of this fragment to other fragments. The present invention is very useful for forming insulinotropic peptides such as GLP-1(7-36) and its natural and non-natural counterparts.
摘要:
An amplifier is provided that includes an output portion that sources and sinks current associated with an output load and an amplification portion that is biased by a relatively small bias current with respect to an output current of the amplifier. The amplification portion provides an amplified output signal to the output portion. The amplifier further comprises at least one impedance component coupled between the output portion and the amplification portion to alter at least one pole associated with the amplifier to mitigate instability of the amplifier related to the relatively small bias current.
摘要:
A wireless communication method, a Base Station (BS), an indoor communication system, and a handover method are disclosed. In this method, the working frequency of the service carrier of the indoor coverage system is preset to be different from the working frequency of the service carrier of the outdoor macro cell system, the working frequency of the beacon carrier of the indoor coverage system is preset to be the same as the working frequency of the service carrier of the outdoor macro cell system, and a common channel is allocated on the beacon carrier of the indoor coverage system. With the present invention, the MS can reside in and hand over to the expected wireless communication system smoothly, the intra-frequency interference and pilot pollution between the neighboring wireless communication systems are overcome, and the communication quality of the wireless communication system is improved.
摘要:
The present invention is a system and method for generating predictions for various parameters in a reservoir. The invention includes receiving input data characterizing the reservoir and determining transient areas. The transient areas are determined by receiving data from the reservoir, transforming the data using discrete wavelet transformation to produce transformed data, removing outliers from the transformed data, identifying and reducing noise from in the transformed data and then detecting transient areas in the transformed data. A computer model is produced in response to the transient data and predictions for parameters in the reservoir are determined. These predictions are verified by comparing predictive values with a reservoir model and then the predictions for the various parameters can be used.
摘要:
Methods and apparatuses for accessing data within programmable graphics hardware are provided. According to one aspect, a user inserts special log commands into a software program, which is compiled into instructions for the programmable graphics hardware to execute. The hardware writes data to an external memory during runtime according to a flow control protocol, and the software driver reads the data from the memory to display to the user.
摘要:
A method and device for performing and processing user-defined clipping in object space to reduce the number of computations needed for the clipping operation. The method and device also combine the modelview transformation of the vertex coordinates with projection transform. The user-defined clipping in object space provides a higher performance and less power consumption by avoiding generation of eye coordinates if there is no lighting. The device includes a driver for the user-defined clipping in the object space to perform dual mode user-defined clipping in object space when a lighting function is disabled and in eye space when the lighting function is enabled.
摘要:
The present invention relates to the preparation of insulinotropic peptides that are synthesized using a solid and solution phase (“hybrid”) approach. Generally, the approach includes synthesizing three different peptide intermediate fragments using solid phase chemistry. Solution phase chemistry is then used to add additional amino acid material to one of the fragments. The fragments are then coupled together in the solid solution phase. The use of a pseudoproline in one of the fragments eases solid phase synthesis of that fragment and also eases subsequent solution phase coupling of this fragment to other fragments. The present invention is very useful for forming insulinotropic peptides such as GLP-1(7-36) and its natural and non-natural counterparts.
摘要:
A system and method for a network security system are provided. The method includes providing a master device and a backup device within a cluster of network security devices, providing the backup device with state information for the master device, detecting failure in the cluster and using the state information to recover from the failure.
摘要:
An impedance compensation circuit generates per-group pull-up impedance information and per-group pull-down impedance information to calibrate a plurality of input/output pads and dynamically updates impedance information on a per channel basis. A group refers to a group of I/O pads having similar output drive strengths in a channel. A channel refers to all I/O pads, which collectively provide a bus interface to an external device. For example, all the I/O pads interfacing with a memory module may be grouped into a channel, and address I/O pads in a channel may be arranged into a “group.” Memory I/O pads may be grouped together into a channel since memory interface pads have input/output characteristics that may be different from those of other types of I/O pads in the chip. According to one embodiment, per-group programmable offset information provides calibration information that may be different for each group in each channel.
摘要:
A caching system for increasing the operation concurrency between a cache module and a memory module by comparing received memory block identifiers, which correspond to texels needed for pixel composition, with memory block identifiers corresponding to texels locally stored within the cache module. If the received memory block identifiers match the memory block identifiers corresponding to locally cached texels, the system transmits these texels to a texture filter unit for pixel composition. If the received memory block identifiers do not match memory block identifiers corresponding to the locally cached texels, the system retrieves these texels from the memory module as fast as possible and then updates the cache module with the new texels. A plurality of first in, first out buffers are used to assist a controller module with synchronizing the transmission of the texels from the cache module and the overwriting of the texels received from the memory module into the cache module. Once locally cached, these texels also are transmitted to the texture filter unit for pixel composition.