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31.发明授权公开(公告)号：US09808214B2
公开(公告)日：2017-11-07
申请号：US14330533
申请日：2014-07-14
Applicant: Hologic, Inc.
Inventor： Andrew P. Smith , Jay A. Stein , Ken Defreitas , Ian Shaw , Zhenxue Jing , Loren Niklason , Baorui Ren , Christopher Ruth
CPC classification number: A61B6/502 , A61B6/025 , A61B6/027 , A61B6/032 , A61B6/04 , A61B6/0414 , A61B6/405 , A61B6/4441 , A61B6/4447 , A61B6/461 , A61B6/463 , A61B6/466 , A61B6/482 , A61B6/5235
Abstract: A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
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公开(公告)号：US09498175B2
公开(公告)日：2016-11-22
申请号：US14057061
申请日：2013-10-18
Applicant: Hologic, Inc.
Inventor： Jay Stein , Andrew P. Smith , Zhenxue Jing , Loren Niklason
CPC classification number: A61B6/025 , A61B6/405 , A61B6/4417 , A61B6/502 , A61B6/5235 , A61B6/5247 , A61B6/542 , A61B8/0825 , G01N23/046
Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.
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公开(公告)号：US20140044230A1
公开(公告)日：2014-02-13
申请号：US14057061
申请日：2013-10-18
Applicant: Hologic, Inc.
Inventor： Jay Stein , Andrew P. Smith , Zhenxue Jing , Loren Niklason
IPC: A61B6/02
CPC classification number: A61B6/025 , A61B6/405 , A61B6/4417 , A61B6/502 , A61B6/5235 , A61B6/5247 , A61B6/542 , A61B8/0825 , G01N23/046
Abstract: A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.
Abstract translation: 乳房成像系统利用二维和三维成像的综合优势，提供具有改善的敏感性，特异性和患者给药的乳腺癌筛查。 断层合成系统支持以比用于获取二维图像的剂量低的剂量获取三维图像。 低剂量三维图像可以用于质量检测，而二维图像可以用于钙化检测。 以低剂量获得断层合成数据除了质量检测之外还提供了许多优点，包括扫描时间的减少以及X射线管上的磨损和撕裂。 这种布置提供了具有高灵敏度和特异性并减少患者给药的乳腺癌筛查系统。
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34.发明申请Method and System for Controlling X-Ray Focal Spot Characteristics for Tomosynthesis and Mammography Imaging 有权控制X射线焦点特征的方法和系统，用于骨骼肌合成和乳房X线照相成像公开(公告)号：US20130259192A1
公开(公告)日：2013-10-03
申请号：US13905264
申请日：2013-05-30
Applicant: Hologic, Inc.
Inventor： Baorui Ren , Jay Stein , Zhenxue Jing , Andrew Smith
IPC: A61B6/00
Abstract: An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position. In a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
Abstract translation: 描述了一种X射线管，其包括用于通过改变焦点特性（包括焦点尺寸和焦斑位置）来增加在存在移动的X射线源的情况下增加x射线图像清晰度的部件。 在第一布置中，静止焦点在与x射线源的移动相反的方向上移动，使得在断层合成曝光期间相对于成像对象和/或检测器中的一个，有效焦点位置基本上固定在空间中 。 在第二种布置中，静态焦点的尺寸增加，并且由此导致的管电流的增加降低了曝光时间并伴随着模糊效果。 这些方法可以单独使用或组合使用; 例如具有较大可移动静电焦点的X射线管将导致完全利用x射线管发生器的系统，提供具有减少的模糊的高质量图像，并且由于曝光时间的减少可能扫描 病人更快
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35.发明授权公开(公告)号：US12042318B2
公开(公告)日：2024-07-23
申请号：US17834181
申请日：2022-06-07
Applicant: Hologic, Inc.
Inventor： Brad Michael Keller , Zhenxue Jing
Abstract: Techniques for patient positioning quality assurance prior to mammographic image acquisition are described. A system may include an x-ray source configured to expose human tissue to radiation. An x-ray detector module may be configured to detect the radiation and generate a pre-diagnostic image of the human tissue. A position analysis module may be configured to receive the pre-diagnostic image and determine whether the human tissue is positioned correctly based upon one or more predefined positioning criteria. A non-transitory computer-readable storage medium may be configured to store the results of the positional analysis module determination. A display may be configured to display the determination of the position analysis module within a user interface. Other embodiments are described and claimed.
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Patent Agency Ranking
公开(公告)号：US20220386969A1
公开(公告)日：2022-12-08
申请号：US17843417
申请日：2022-06-17
Applicant: Hologic, Inc.
Inventor： Andrew P. Smith , Jay A. Stein , Zhenxue Jing , Baorui Ren , Loren Niklason , Christopher Ruth , Ian Shaw
Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
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公开(公告)号：US11478206B2
公开(公告)日：2022-10-25
申请号：US17009098
申请日：2020-09-01
Applicant: Hologic, Inc.
Inventor： Andrew P. Smith , Jay Stein , Kenneth Defreitas , Ian Shaw , Zhenxue Jing , Loren Niklason , Baorui Ren , Christopher Ruth
Abstract: Systems and methods for breast x-ray tomosynthesis that enhance spatial resolution in the direction in which the breast is flattened for examination. In addition to x-ray data acquisition of 2D projection tomosynthesis images ETp1 over a shorter source trajectory similar to known breast tomosynthesis, supplemental 2D images ETp2 are taken over a longer source trajectory and the two sets of projection images are processed into breast slice images ETr that exhibit enhanced spatial resolution, including in the thickness direction of the breast. Additional features include breast CT of an upright patient's flattened breast, multi-mode tomosynthesis, and shielding the patient from moving equipment.
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公开(公告)号：US11406332B2
公开(公告)日：2022-08-09
申请号：US16439131
申请日：2019-06-12
Applicant: Hologic, Inc.
Inventor： Andrew P. Smith , Jay A. Stein , Zhenxue Jing , Baorui Ren , Loren Niklason , Christopher Ruth , Ian Shaw
Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
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39.发明授权公开(公告)号：US10959694B2
公开(公告)日：2021-03-30
申请号：US15875095
申请日：2018-01-19
Applicant: Hologic, Inc.
Inventor： Zhenxue Jing , Georgia Hitzke , Donald Kennedy , Andrew Smith , Jay A. Stein
Abstract: A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.
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40.发明申请公开(公告)号：US20200085393A1
公开(公告)日：2020-03-19
申请号：US16567910
申请日：2019-09-11
Applicant: Hologic, Inc.
Inventor： Yiheng Zhang , Zhenxue Jing , Christopher Ruth
Abstract: Methods and systems for medical imaging including synthesizing virtual projections from acquired real projections and generating reconstruction models and images based on the synthesized virtual projections and acquired real projections. For example, first x-ray imaging data is generated from a detected first x-ray emission at a first angular location and second x-ray imaging data is generated from a detected second x-ray emission at a second angular location. Based on at least the first x-ray imaging data and the second x-ray imaging data, third x-ray imaging data for a third angular location relative to the breast may be synthesized. An image of the breast may be displayed or generated from the third x-ray imaging data.
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