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公开(公告)号：US20160289664A1
公开(公告)日：2016-10-06
申请号：US14674971
申请日：2015-03-31
Applicant: General Electric Company
Inventor： Vasile Bogdan Neculaes , Juan Jose Becerra , Christine Angela Morton , Andrew Soliz Torres , Antonio Caiafa
CPC classification number: C12N5/0644 , C12M35/02 , C12N2529/00
Abstract: Methods and systems for generating a tunable or customizable activated product composition are related. In certain embodiments, one or more of electric pulse parameters, flow rate, or sample container size are varied so as to generate the activated product composition. The activated product composition may be customized or optimized based for a particular patient or procedure.
Abstract translation: 用于生成可调谐或可定制的活化产品组合物的方法和系统是相关的。 在某些实施例中，电脉冲参数，流速或样本容器尺寸中的一个或多个被改变以便产生活化的产品组合物。 活化的产品组合物可以针对特定的患者或程序进行定制或优化。
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公开(公告)号：US09153409B2
公开(公告)日：2015-10-06
申请号：US14061509
申请日：2013-10-23
Applicant: General Electric Company
Inventor： Uwe Wiedmann , Antonio Caiafa , Dominique Poincloux
IPC: H01J35/14
CPC classification number: H01J35/14
Abstract: Issues related to maintaining the size of a focal spot on the target material of an X-ray source are addressed by linking the currents used in a magnetic focusing system employed in the X-ray source. The size of the focal spot on the target is less sensitive to current changes applied to the magnetic focusing system due to this linkage.
Abstract translation: 通过连接在X射线源中使用的磁聚焦系统中使用的电流来解决与维持X射线源的目标材料上焦点尺寸有关的问题。 由于这种联动，目标上焦点的大小对施加到磁聚焦系统的电流变化较不敏感。
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公开(公告)号：US12148592B2
公开(公告)日：2024-11-19
申请号：US18497508
申请日：2023-10-30
Applicant: General Electric Company
Inventor： John Scott Price , Ye Bai , Antonio Caiafa , Vasile Bogdan Neculaes , Uwe Wiedmann
IPC: H01J29/68 , B29C64/153 , B29C64/273 , H01J37/30 , H01J37/305 , B33Y30/00
Abstract: A system for melting, sintering, or heat treating a material is provided. The system includes a cathode, an anode, and a focus coil assembly having a quadrupole magnet. The quadrupole magnet includes four poles and a yoke. The four poles are spaced apart and surround a beam cavity. Each of the four poles includes a pole face proximate the beam cavity and an end opposite the pole face. The first and third poles are aligned along an x-axis and configured to have a first magnetic polarity at their respective pole faces and a second magnetic polarity opposite the first magnetic polarity at their respective ends. The second and fourth poles are aligned along a y-axis and configured to have the second magnetic polarity at their respective pole faces and the first magnetic polarity at their respective ends. The yoke surrounds the poles and is coupled to the poles.
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公开(公告)号：US11837428B2
公开(公告)日：2023-12-05
申请号：US16944836
申请日：2020-07-31
Applicant: General Electric Company
Inventor： John Scott Price , Ye Bai , Antonio Caiafa , Vasile Bogdan Neculaes , Uwe Wiedmann
IPC: H01J29/68 , H01J37/30 , B29C64/153 , B29C64/273 , H01J37/305 , B33Y30/00
CPC classification number: H01J29/68 , B29C64/153 , B29C64/273 , H01J37/3002 , H01J37/305 , B33Y30/00 , H01J2237/1415
Abstract: A system for melting, sintering, or heat treating a material is provided. The system includes a cathode, an anode, and a focus coil assembly having a quadrupole magnet. The quadrupole magnet includes four poles and a yoke. The four poles are spaced apart and surround a beam cavity. Each of the four poles includes a pole face proximate the beam cavity and an end opposite the pole face. The first and third poles are aligned along an x-axis and configured to have a first magnetic polarity at their respective pole faces and a second magnetic polarity opposite the first magnetic polarity at their respective ends. The second and fourth poles are aligned along a y-axis and configured to have the second magnetic polarity at their respective pole faces and the first magnetic polarity at their respective ends. The yoke surrounds the poles and is coupled to the poles.
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公开(公告)号：US20190336578A1
公开(公告)日：2019-11-07
申请号：US16514662
申请日：2019-07-17
Applicant: General Electric Company
Inventor： Vasile Bogdan Neculaes , Andrew Soliz Torres , Antonio Caiafa , Brian Dun-Lan Lee , Allen Lawrence Garner
IPC: A61K38/18 , C12N13/00 , A61K35/19 , G01N33/49 , G01N33/487
Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
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Patent Agency Ranking
公开(公告)号：US10290460B2
公开(公告)日：2019-05-14
申请号：US15258631
申请日：2016-09-07
Applicant: General Electric Company
Inventor： Michael John Utschig , Uwe Wiedmann , Bruno Kristiaan Bernard De Man , Sergio Lemaitre , Mark Alan Frontera , Antonio Caiafa , Jiahua Fan , Adam Budde
Abstract: An X-ray tube is provided. The X-ray tube includes an electron beam source including a cathode configured to emit an electron beam. The X-ray tube also includes an anode assembly including an anode configured to receive the electron beam and to emit X-rays when impacted by the electron beam. The X-ray tube further includes a gridding electrode disposed about a path of the electron beam between the electron beam source and the anode assembly. The gridding electrode, when powered at a specific level, is configured to grid the electron beam in synchronization with planned transitions during a dynamic focal spot mode.
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公开(公告)号：US10205379B2
公开(公告)日：2019-02-12
申请号：US15399309
申请日：2017-01-05
Applicant: General Electric Company
Inventor： Antonio Caiafa
Abstract: A power system includes a first unit block having first resonant circuitry that receives power from a DC bus, a first controlled rectifier that provides a first portion of power to one or more loads at a first voltage level, and a first transformer coupled between the first resonant circuitry and the first controlled rectifier. A second unit block includes second resonant circuitry that receives power from the DC bus, a second controlled rectifier configured to provide a second portion of power to the one or more loads at a second voltage level, and a second transformer coupled between the resonant circuitry and the controlled rectifier. The first and second unit blocks are coupled in series to output a summation waveform.
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公开(公告)号：US20180237764A1
公开(公告)日：2018-08-23
申请号：US15955377
申请日：2018-04-17
Applicant: General Electric Company
Inventor： Antonio Caiafa , Vasile Bogdan Neculaes , Allen Lawrence Garner , Andrew Soliz Torres
Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
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公开(公告)号：US20180123350A1
公开(公告)日：2018-05-03
申请号：US15339331
申请日：2016-10-31
Applicant: General Electric Company
Inventor： Antonio Caiafa , Ahmed Elasser , Dong Dong
IPC: H02J4/00
CPC classification number: H02J3/005
Abstract: A switching system includes a transformer and a switching assembly for controlling conduction of current from a power source to a first load along a power cable. The switching assembly includes a switch cell conductively coupled to the power cable. The transformer has a primary winding and a secondary winding. The secondary winding is conductively coupled to the switch cell. The primary winding is conductively coupled to a switch controller via the power cable. The transformer is configured to receive an activation control signal from the switch controller at the primary winding via the power cable and convey the activation control signal to the switch cell via the secondary winding. The switch cell is configured to activate and conduct the current from the power source to the first load along the power cable responsive to receiving the activation control signal from the switch controller.
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公开(公告)号：US09708597B2
公开(公告)日：2017-07-18
申请号：US14158106
申请日：2014-01-17
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Antonio Caiafa , Vasile Bogdan Neculaes , Allen Lawrence Garner , Andrew Soliz Torres
CPC classification number: C12N13/00 , A61B5/150755 , C12M35/02 , G01N33/49 , H03K3/53
Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
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