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公开(公告)号：US11351547B2
公开(公告)日：2022-06-07
申请号：US16610318
申请日：2019-03-26
Inventor： Yue Geng , Peizhi Cai , Fengchun Pang , Le Gu , Chuncheng Che , Nan Zhao
IPC: B01L3/00
Abstract: Micro-fluidic chip comprises substrate and plurality of driving circuits on substrate, each of plurality of driving circuits comprising: driving electrode comprising first electrode plate and second electrode plate made of different materials on substrate, first electrode plate being electrically coupled to second electrode plate; and detecting sub-circuit comprising first signal terminal electrically coupled to first electrode plate and second signal terminal electrically coupled to second electrode plate, wherein micro-fluidic chip further comprises: voltage supply sub-circuit configured to supply driving voltage to first signal terminal to control droplet to move toward driving circuit during droplet driving stage, and configured to supply constant voltage to first signal terminal, during temperature detecting stage, and wherein detecting sub-circuit is configured to measure voltage difference between first signal terminal and second signal terminal, and obtain temperature of droplet on second electrode plate according to voltage difference, during temperature detecting stage.
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公开(公告)号：US11325128B2
公开(公告)日：2022-05-10
申请号：US16464603
申请日：2018-06-29
Inventor： Yue Geng , Peizhi Cai , Chuncheng Che , Fengchun Pang
IPC: B01L3/00
Abstract: The present application provides a digital microfluidic device. The digital microfluidic device includes a base substrate; and an electrode array including a plurality of discrete electrodes continuously arranged on the base substrate. The plurality of discrete electrodes can be grouped into a plurality of first electrode groups, each of which including a plurality of directly adjacent discrete electrodes. The plurality of discrete electrodes can be alternatively grouped into a plurality of second electrode groups, each of which including a plurality of directly adjacent discrete electrodes.
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公开(公告)号：US11168361B2
公开(公告)日：2021-11-09
申请号：US16072923
申请日：2017-12-15
Inventor： Fengchun Pang , Peizhi Cai , Yue Geng
IPC: C12Q1/6869 , C12Q1/6837
Abstract: A chip, a detection system and a gene sequencing method are provided. When the chip is used for gene sequencing, sample genes and reversible terminating nucleotides are added into micropores and matched therein to release hydrogen ions such that a Nernst potential is induced on an ion-sensitive film surface, and a voltage is applied to the transparent electrode layer to generate an electric field, thereby controlling the switching layer to change its state, and then a base type of the genes is determined based on a type of reversible terminating nucleotide corresponding to information of light emitted from the switching layer upon changes in the state of the switching layer, thereby gene sequencing is achieved.
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公开(公告)号：US20210331162A1
公开(公告)日：2021-10-28
申请号：US16626490
申请日：2019-07-26
Inventor： Nan Zhao , Peizhi Cai , Haochen Cui , Yuelei Xiao , Fengchun Pang , Le Gu , Yingying Zhao , Hui Liao , Yue Geng , Wenliang Yao
Abstract: A microfluidic apparatus is provided. The microfluidic apparatus includes an electrochromic layer including a plurality of individually independently addressable regions; a microfluidic layer defining a microfluidic channel for allowing a microfluid to pass therethrough; and a plurality of photodetectors configured to detect light transmit through the microfluid. The electrochromic layer is configured to be switched between a first state in which the plurality of individually independently addressable regions of the electrochromic layer are substantially transmissive, and a second state in which at least a first one of the plurality of individually independently addressable regions of the electrochromic layer in a region corresponding to a position of the microfluid is substantially transmissive, at least a second one of the plurality of individually independently addressable regions of the electrochromic layer outside the region corresponding to the position of the microfluid is substantially non-transmissive.
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公开(公告)号：US20160125955A1
公开(公告)日：2016-05-05
申请号：US14806872
申请日：2015-07-23
Inventor： Fengchun Pang
IPC: G11C19/28
CPC classification number: G11C19/287 , G09G2310/0286
Abstract: A shift register, driving method thereof and a gate driving circuit are disclosed, wherein the shift register comprises an input module, a reset module, a first output module, a second output module and a control module. The shift register uses the first clock signal to control the second node, and then controls the signal output by the signal output terminal by alternate high/low levels of the second node and the second clock signal, such that the signal output terminal can always output signals to eliminate noises and stabilize row output signals. In addition, since the second node has alternate high/low levels, the life span of the shift register can be protected.
Abstract translation: 公开了一种移位寄存器，其驱动方法和门驱动电路，其中移位寄存器包括输入模块，复位模块，第一输出模块，第二输出模块和控制模块。 移位寄存器使用第一时钟信号来控制第二节点，然后通过第二节点和第二时钟信号的交替高/低电平控制由信号输出端子输出的信号，使得信号输出端子可以总是输出 信号消除噪声并稳定行输出信号。 此外，由于第二节点具有交替的高/低电平，所以可以保护移位寄存器的使用寿命。
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Patent Agency Ranking
公开(公告)号：US11865538B2
公开(公告)日：2024-01-09
申请号：US16757902
申请日：2019-03-27
Inventor： Wenliang Yao , Nan Zhao , Peizhi Cai , Fengchun Pang , Yue Geng , Le Gu , Yuelei Xiao , Hui Liao , Yingying Zhao , Bolin Fan
IPC: B01L3/00 , G01N33/487 , H01L27/12
CPC classification number: B01L3/502715 , G01N33/48707 , H01L27/1214 , B01L2300/0645 , B01L2300/0819
Abstract: A biological detection chip, a biological detection device, and a detection method thereof are disclosed. The biological detection chip includes a first base substrate and a plurality of detection units arranged in an array along a row direction and a column direction on the first base substrate. Each of the plurality of detection units includes a thin film transistor and an electrode, the thin film transistor is on the first base substrate and includes a gate electrode, a source electrode, and a drain electrode, and the electrode is on a side of the thin film transistor away from the first base substrate and is connected to the drain electrode, and the electrode is configured to carry a biological material to be detected.
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公开(公告)号：US11691147B2
公开(公告)日：2023-07-04
申请号：US16641126
申请日：2019-07-26
Inventor： Mingyang Lv , Yue Li , Yanchen Li , Jinyu Li , Dawei Feng , Yu Zhao , Dong Wang , Wang Guo , Hailong Wang , Yue Geng , Peizhi Cai , Fengchun Pang , Le Gu , Chuncheng Che , Haochen Cui , Yingying Zhao , Nan Zhao , Yuelei Xiao , Hui Liao
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502792 , B01L2200/10 , B01L2300/0645 , B01L2300/165 , B01L2400/0427
Abstract: A digital microfluidic chip and a digital microfluidic system. The digital microfluidic chip comprises: an upper substrate and a lower substrate arranged opposite to each other; multiple driving circuits and multiple addressing circuits disposed between the lower substrate and the upper substrate; and a control circuit, electrically connected to the driving circuits and the addressing circuits. The control circuit is configured to apply, in a driving stage, a driving voltage to each driving circuit, such that a droplet is controlled to move inside a droplet accommodation space according to a set path, measure, in a detection stage, after a bias voltage is applied to each addressing circuit, a charge loss amount of each addressing circuit, and to determine the position of the droplet according to the charge loss amount. The charge loss amount of each addressing circuit is related to the intensity of received external light.
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公开(公告)号：US11498068B2
公开(公告)日：2022-11-15
申请号：US16632931
申请日：2019-01-02
Inventor： Wenliang Yao , Haochen Cui , Peizhi Cai , Yuelei Xiao , Fengchun Pang , Yue Geng , Le Gu , Nan Zhao , Hui Liao , Yingying Zhao , Chuncheng Che
IPC: B01L3/00
Abstract: A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
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39.发明授权公开(公告)号：US11351546B2
公开(公告)日：2022-06-07
申请号：US16314679
申请日：2018-06-08
Inventor： Yue Geng , Peizhi Cai , Fengchun Pang , Le Gu , Chuncheng Che , Hailin Xue , Xibin Shao
IPC: B01L3/00
Abstract: A microfluidic chip and controlling method are provided. The microfluidic chip includes a microfluidic substrate, comprising a first substrate, a droplet driving assembly over the first substrate, and a temperature detection assembly. The droplet driving assembly includes a first electrode layer having a plurality of control electrodes, and each of the plurality of control electrodes is configured as part of a driving unit to drive a droplet to move along a predetermined path over the microfluidic substrate. The temperature detection assembly comprises at least one temperature sensor. The at least one temperature sensor positionally corresponds to the plurality of control electrodes such that each of the at least one temperature sensor detects a temperature at a position associated with one of the plurality of control electrodes corresponding to the each of the at least one temperature sensor.
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公开(公告)号：US11219900B2
公开(公告)日：2022-01-11
申请号：US16334126
申请日：2018-09-12
Inventor： Fengchun Pang , Peizhi Cai , Yue Geng , Le Gu , Chuncheng Che , Hailin Xue , Xibin Shao
IPC: B01L3/00 , H01L27/12 , H01L27/144
Abstract: A digital microfluidic device includes a thin film transistor driving substrate. The thin film transistor driving substrate includes a first base substrate; a plurality of sample actuating units; a plurality of sample position detecting units; a dielectric insulating layer on a side of the plurality of sample actuating units and the plurality of sample position detecting units distal to the first base substrate; and a first hydrophobic layer on a side of the dielectric insulating layer distal to the first base substrate. Each of the plurality of sample actuating units includes a first electrode configured to drive transportation of a liquid droplet on the digital microfluidic device. Each of the plurality of sample position detecting units includes a photosensor configured to detect presence or absence of the liquid droplet on a position corresponding to the photosensor.
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