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公开(公告)号：US11439801B2
公开(公告)日：2022-09-13
申请号：US17108517
申请日：2020-12-01
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett
IPC分类号： A61M29/02 , A61L29/16 , A61M25/10 , A61K31/337 , A61L29/08
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US20210361918A1
公开(公告)日：2021-11-25
申请号：US17255701
申请日：2020-02-21
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett , David Hendrickson
摘要： A balloon catheter for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen; the ballon catheter comprising: An elongated balloon; a coating layer overlying an exterior surface of the balloon wherein the coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent; and a length-control mechanism (600) which stretches and elongates the balloon during deflation, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.
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公开(公告)号：US10994103B2
公开(公告)日：2021-05-04
申请号：US17080140
申请日：2020-10-26
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett , David Hendrickson
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US20210113823A1
公开(公告)日：2021-04-22
申请号：US17108517
申请日：2020-12-01
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US20210077666A1
公开(公告)日：2021-03-18
申请号：US17107136
申请日：2020-11-30
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett
IPC分类号： A61L29/16 , A61P31/00 , A61P37/06 , A61K31/337 , A61K31/439 , A61L29/08
摘要： Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.
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公开(公告)号：US20210052864A1
公开(公告)日：2021-02-25
申请号：US17080140
申请日：2020-10-26
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett , David Hendrickson
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US10850076B2
公开(公告)日：2020-12-01
申请号：US16519720
申请日：2019-07-23
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett
IPC分类号： A61M25/10 , A61K31/337 , A61K31/436 , A61L27/28 , A61B1/307 , B29D22/02
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US10806830B2
公开(公告)日：2020-10-20
申请号：US16135436
申请日：2018-09-19
申请人： Urotronic, Inc.
发明人： Lixiao Wang , Peter Barnett , David Hendrickson
摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
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公开(公告)号：US10675386B2
公开(公告)日：2020-06-09
申请号：US16267434
申请日：2019-02-05
申请人： Urotronic, Inc.
发明人： Lixiao Wang
摘要： Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
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公开(公告)号：US20190167854A1
公开(公告)日：2019-06-06
申请号：US16267434
申请日：2019-02-05
申请人： Urotronic, Inc.
发明人： Lixiao Wang
摘要： Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
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