公开(公告)号：US10516949B2

公开(公告)日：2019-12-24

申请号：US15926876

申请日：2018-03-20

Applicant: EARLENS CORPORATION

Inventor： Sunil Puria ,  Jonathan P. Fay ,  Lee Felsenstein ,  James Stone ,  Mead C. Killion ,  Vincent Pluvinage

IPC: H04R23/00 ,  H04R25/00 ,  A61N1/36

Abstract: A device to transmit an audio signal comprises at least one light source configured to transmit the audio signal with at least one wavelength of light. At least one detector is configured to detect the audio signal and generate at least one electrical signal in response to the at least one wavelength of light. A transducer is supported with and configured to vibrate at least one of an eardrum, an ossicle or a cochlea. Active circuitry is coupled to the transducer to drive the transducer in response to the at least one electrical signal, so as to provide the user with high quality sound.

公开(公告)号：US10516946B2

公开(公告)日：2019-12-24

申请号：US15706208

申请日：2017-09-15

Applicant: EarLens Corporation

Inventor： Sunil Puria ,  Micha Rosen ,  Jonathan P. Fay ,  Paul Rucker ,  James Stone

IPC: H04R11/02 ,  H04R17/00 ,  H04R25/02 ,  H04R25/00 ,  H04R23/00

Abstract: A device to transmit an audio signal to a user comprises a transducer and a support. The support is configured for placement on the eardrum to drive the eardrum. The transducer is coupled to the support at a first location to decrease occlusion and a second location to drive the eardrum. The transducer may comprise one or more of an electromagnetic balanced armature transducer, a piezoelectric transducer, a magnetostrictive transducer, a photostrictive transducer, or a coil and magnet. The device may find use with open canal hearing aids.

公开(公告)号：US10471255B2

公开(公告)日：2019-11-12

申请号：US15410692

申请日：2017-01-19

Applicant: Incube Labs, LLC

Inventor： Mir Imran

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/372

Abstract: A system for controlling urination in a patient includes an implantable controller and an external device. The implantable controller includes circuitry and electrodes for stimulating the pudenal nerves in order to control urination. In addition, the implantable controller includes sensors for determining information on bladder fullness and for transmitting such information to an external device which is used for controlling the implanted controller. The external device will display when bladder filling exceeds a safe threshold level, allowing the patient and a caregiver to take appropriate steps to allow the patient to urinate.

公开(公告)号：US10363021B2

公开(公告)日：2019-07-30

申请号：US15424119

申请日：2017-02-03

Applicant: CARDIVA MEDICAL, INC.

Inventor： Zia Yassinzadeh ,  Jeffrey I. Weitz ,  Alan Stafford

IPC: A61B17/08 ,  A61B17/00 ,  A61B17/34 ,  A61B90/00

Abstract: Vascular closure devices and methods for closing a blood vessel puncture site disposed at a distal end of a tissue tract are described. A combination of the body's own natural mechanism with chemical and/or biological agents is relied upon to accelerate the hemostatic process. Included are steps of introducing a closure device through the tissue tract and deploying an expansible member at a distal end of the device within the blood vessel to occlude the puncture site. A sealing member disposed proximal the expansible member is then displaced by retracting and tensioning a coil spring so as to expose a chemical and/or biological region or release region of the device. The retraction and tensioning of the coil spring is limited by a coupling member. Exposure of blood and tissue to the chemical and/or biological sealing member promotes the clotting processing to accelerate the occlusion process in the tract.

公开(公告)号：US10335596B2

公开(公告)日：2019-07-02

申请号：US15385729

申请日：2016-12-20

Applicant: NALU MEDICAL, INC.

Inventor： Anatoly Yakovlev ,  Daniel Pivonka ,  Logan Palmer

IPC: A61N1/378 ,  A61N1/36 ,  A61N1/05 ,  A61N1/372 ,  A61N2/00 ,  A61B5/053 ,  A61B5/04 ,  A61B5/0488 ,  A61B5/145 ,  A61B5/11 ,  A61B5/00 ,  G06F19/00 ,  G16H40/67 ,  H02J7/02 ,  H02J50/00

Abstract: Systems, devices, and methods for neurostimulation using a combination of implantable and external devices to treat pain are disclosed.

公开(公告)号：US10327747B2

公开(公告)日：2019-06-25

申请号：US15237493

申请日：2016-08-15

Applicant: Cardiva Medical, Inc.

Inventor： Zia Yassinzadeh ,  Delfin Pelayo

IPC: A61B17/00 ,  A61B90/00 ,  A61B17/22

Abstract: Apparatus for sealing a vascular wall penetration disposed at the end of the tissue tract comprises a shaft, an occlusion element, a hemostatic implant, and a protective sleeve. The apparatus is deployed through the tissue tract with the occlusion element temporarily occluding the vascular wall penetration and inhibiting backbleeding therethrough. The hemostatic implant, which will typically be a biodegradable polymer such as collagen carrying an anti-proliferative agent or coagulation promoter, will then be deployed from the sealing apparatus and left in place to enhance closure of the vascular wall penetration with minimum scarring. The implant may be radiopaque to allow observation before release.

公开(公告)号：US10314891B2

公开(公告)日：2019-06-11

申请号：US15971395

申请日：2018-05-04

Applicant: Rani Therapeutics, LLC

Inventor： Mir Imran

IPC: A61K38/22 ,  A61M25/10 ,  A61M5/00 ,  A61K38/26 ,  A61K31/155 ,  A61K9/48 ,  A61K9/00 ,  A61M31/00 ,  A61K38/28

Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

公开(公告)号：US10286226B2

公开(公告)日：2019-05-14

申请号：US15074568

申请日：2016-03-18

Applicant: D-Rev: Design for the Other Ninety Percent

Inventor： Jayanth Chakravarthy ,  Krista Donaldson ,  Peter Russo ,  Mohan Sancheti ,  Randy Schwemmin ,  Garrett Spiegel

IPC: A61N5/06 ,  G01J1/04 ,  G01J1/44

Abstract: A phototherapy device for treating neonatal hyperbilirubinemia comprises a plurality of LEDs coupled to a support structure configured to absorb and dissipate heat generated by the LEDs without requiring a fan. The LEDs provide a uniform dose of radiation on a treatment surface of the subject over a distance range of 20 cm to 45 cm. The support structure can comprise a heat-conductive metal plate. The LEDs have an emission range of 400 nm to 520 and a light output intensity of at least 30 μW/cm2/nm and at most 65 μW/cm2/nm at the treatment surface. The device can be adjustably coupled to a mounting structure. Power supplied to the LEDs is adjustable based on the total number of hours of use of he LEDs, the intensity of the LED radiation, the distance between the LEDs and the treatment surface, and/or the tilt or orientation of the phototherapy device.

公开(公告)号：US10252039B2

公开(公告)日：2019-04-09

申请号：US15668421

申请日：2017-08-03

Applicant: Rani Therapeutics, LLC

Inventor： Mir Imran

IPC: A61K38/26 ,  A61M31/00 ,  A61K31/155 ,  A61M5/20 ,  A61K38/27 ,  A61K38/28 ,  A61K9/48 ,  A61M5/168 ,  A61K38/22 ,  A61K45/06 ,  A61K38/29 ,  A61K9/00 ,  A61K38/17 ,  A61M5/172 ,  A61M5/14 ,  A61M5/142

Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to an actuator having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

公开(公告)号：US10231656B2

公开(公告)日：2019-03-19

申请号：US14794037

申请日：2015-07-08

Applicant: NONINVASIX, INC.

Inventor： Rinat Esenaliev ,  Donald S. Prough ,  Yuriy Petrov ,  Irene Petrov ,  George Saade ,  Gayle L. Olson ,  Tommy G. Cooper

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1464 ,  A61B5/1459

Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.