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公开(公告)号：US11059875B2
公开(公告)日：2021-07-13
申请号：US16269984
申请日：2019-02-07
Inventor： Yong Mahn Han , Jung Yun Choi , Bum Soo Kim
IPC: C07K14/51 , A61K31/7088 , A61K31/5377 , A61K31/4439 , A61K31/4709 , A61K31/519 , A61P9/00 , C12Q1/02 , G01N33/50
Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of CFC (cardiofaciocutaneous) syndrome comprising a TGF-β signaling pathway inhibitor or a BMP signaling pathway activator. The treatment of SB-431542 or BMP4 protein was confirmed to increase the ALP activity and bone mineral deposition in the osteoblasts originated from the induced pluripotent stem cells derived from CFC syndrome patients. Thus, the TGF-β signaling pathway inhibitor containing SB-431542 or the BMP signaling pathway activator containing BMP4 protein can be effectively used for the prevention or treatment of CFC syndrome.
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公开(公告)号：US20210211408A1
公开(公告)日：2021-07-08
申请号：US17125551
申请日：2020-12-17
Inventor： Phillip A. Porras , Vinod Yegneswaran , Jaehyun Nam , Seungwon Shin
Abstract: A method, apparatus and system for providing security for a container network having a plurality of containers includes establishing a network stack for each of the plurality of containers of the container network, determining network and policy information from active containers, based on a set of pre-determined inter-container dependencies for the plurality of containers learned from the determined network and policy information, configuring container access in the container network to be limited to only containers of the plurality of containers that are relevant to a respective communication, and configuring inter-container traffic in the container network to be directed only from a source container into a destination container in a point-to-point manner such that exposure of the inter-container traffic to peer containers is prevented.
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公开(公告)号：US20210203069A1
公开(公告)日：2021-07-01
申请号：US16786034
申请日：2020-02-10
Inventor： Chulsoon PARK , Honghyun BAE
Abstract: A dual-polarized antenna with high isolation is disclosed. A first differential signal feeding unit extends from a first input port toward one side of a patch radiator through a dielectric substrate, and is branched into a balun structure to provide first and second feeding probes for differentially feeding vertically polarized signals to opposite first and second portions of the patch radiator. A second differential signal feeding unit extends from a second input port toward another side of the patch radiator through the dielectric substrate, and is branched into the balun structure to provide third and fourth feeding probes for differentially feeding horizontally polarized signals to opposite third and fourth portions of the patch radiator. When feeding the vertically polarized signals through the first and second feeding probes, a virtual ground region in which there is little electric field is formed in the center portion of the patch radiator. The cross-sectional polarization components of the third and fourth probes are also greatly reduced, so that they hardly exist. A soft surface structure surrounding the patch radiator and the first to fourth probes can improve the radiation pattern deterioration caused by diffraction of surface waves.
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公开(公告)号：US20210200626A1
公开(公告)日：2021-07-01
申请号：US17072170
申请日：2020-10-16
Inventor： June-Koo Rhee , Changjun Kim , Kyungdeock Park
Abstract: The present disclosure relates to a method of mitigating errors in quantum circuits constituting a quantum computer, which includes: obtaining a plurality of pieces of first probability matrix information according to a sequence of quantum gates constituting a quantum circuit; obtaining a plurality of pieces of second probability matrix information according to a sequence of quantum gates constituting the quantum circuit; generating a plurality of pieces of differential matrix information based on the plurality of pieces of first and second probability matrix information; and generating error mitigation matrix information corresponding to the quantum circuit using the plurality of pieces of differential matrix information.
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公开(公告)号：US20210197287A1
公开(公告)日：2021-07-01
申请号：US17130641
申请日：2020-12-22
Inventor： Hoon SOHN , Ikgeun JEON , Peipei LIU
Abstract: Disclosed are an integrated inspection system for a 3D printing process using a thermal image and a laser ultrasound wave and a 3D printing system having the inspection system. The inspection system includes a thermal imaging camera for creating a thermal image of a molten pool formed in a printing object when a base material supplied to the printing object is melted by a laser beam irradiated from a 3D printing laser source, a laser ultrasonic device for receiving a laser ultrasonic wave included in the laser beam reflected from the printing object, and a control unit for estimating a physical property of the printing object and detecting a defect of the printing object based on the thermal image created by the thermal imaging camera and the laser ultrasound wave received by the laser ultrasonic device. The thermal imaging camera and the laser ultrasonic device are disposed coaxially with the 3D printing laser source.
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Patent Agency Ranking
316.发明申请公开(公告)号：US20210197286A1
公开(公告)日：2021-07-01
申请号：US17118890
申请日：2020-12-11
Inventor： Hoon SOHN , Ikgeun JEON
Abstract: Disclosed are a method and apparatus of estimating a depth of a molten pool formed during a 3D printing process, and a 3D printing system. A surface temperature of the molten pool is measure by taking a thermal image of a laminated printing object during the 3D printing process with a thermal imaging camera. The measured surface temperature is compared with a melting point of the base material to determine a surface boundary of the molten pool. The maximum lengths in x-axis and y-axis directions of a surface region of the molten pool defined by the surface boundary of the molten pool are determined as a length and a width of the surface of the molten pool, respectively. A maximum depth in the z-axis direction of the molten pool is determined in real time based on the length and width of the surface region of the molten pool.
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317.发明申请公开(公告)号：US20210197283A1
公开(公告)日：2021-07-01
申请号：US17124973
申请日：2020-12-17
Inventor： Hoon SOHN , Ikgeun JEON , Peipei LIU
Abstract: A method of feedback controlling a 3D printing process in real time, and a system therefor are disclosed. The method includes collecting big data, generated through 3D printing experiments, related to process variables of 3D printing, measurement signals, and 3D printing quality of the 3D printing object; building an artificial neural network model by performing machine-learning based on the collected big data; evaluating whether or not a 3D printing quality of the 3D printing object is abnormal in real time based on an actual measurement signal of the 3D printing object and the artificial neural network model; and feedback controlling printing quality of the 3D printing object in real time based on the evaluation result of whether or not the 3D printing quality of the 3D printing object is abnormal.
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公开(公告)号：US20210196555A1
公开(公告)日：2021-07-01
申请号：US17105692
申请日：2020-11-27
Inventor： Ki-Uk KYUNG , Jaeyeon JEONG , Kyujin HYEON , Jungwoo HAN , Kwang-Ok AN , Won-Kyung SONG
Abstract: Disclosed is a wearable robot for assisting a wrist, including: a plurality of flexible actuators; and a control unit configured to control any one of the plurality of flexible actuators to be contracted or relaxed according to a wrist movement of a wearer. Each of the plurality of flexible actuators includes: a driving part which is contractively deformed by a current or transfer heat applied from the control unit or is relaxed when the heat is lost, and a refrigerant circulating part which is implemented to surround the driving part and circulates a refrigerant so that the contractively deformed driving part is cooled under control of the control unit.
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公开(公告)号：US11043647B2
公开(公告)日：2021-06-22
申请号：US16212798
申请日：2018-12-07
Inventor： Yeon Sik Jung , Duk Young Jeon , Geon Yeong Kim , Jin Young Choi , Chul Hee Lee , Hun Hee Lim
Abstract: The present disclosure relates to a quantum dot film including a self-assembled block copolymer, and a quantum dot bonded to the block copolymer, wherein the film has pores with an average diameter of 100-3000 nm inside.
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公开(公告)号：US20210183521A1
公开(公告)日：2021-06-17
申请号：US17115966
申请日：2020-12-09
Inventor： Hyeon-Min BAE , Seokhwan OH , Gibbeum LEE , Myeong Gee KIM
Abstract: The method of operating an image device comprises receiving an input of virtual tissues modeled with an arbitrary shape and a quantitative feature, simulating a TOF change or a signal strength change of ultrasound data having penetrated the virtual tissues modeled with a speed-of-sound distribution or an attenuation coefficient distribution in a first and in a second direction, and creating an image pair representing the TOF change or the signal strength change, creating a speed-of-sound distribution image or an attenuation coefficient distribution image of each of the virtual tissues as a ground truth of an image pair created in the corresponding virtual tissue, and training a first neural network that reconstruct the speed-of-sound distribution image from an input image pair or training a second neural network that reconstructs the attenuation coefficient distribution image from the input image pair.
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