公开(公告)号：US08764687B2

公开(公告)日：2014-07-01

申请号：US12116828

申请日：2008-05-07

Applicant: Michael H Slayton ,  Peter G. Barthe ,  Paul M. Jaeger

Inventor： Michael H Slayton ,  Peter G. Barthe ,  Paul M. Jaeger

IPC: A61N7/00

CPC classification number: A61B8/4281 ,  A61K49/226 ,  G10K11/02 ,  G10K11/30

Abstract: An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.

Abstract translation: 使用封装的耦合器部件耦合声能的示例性系统包括显示器或指示器，控制系统，探针和耦合器部件。 本发明提供一种可调节地配置成执行（i）提供支座，（ii）聚焦或散焦能量和（iii）耦合能量中的至少一个的耦合器部件。 示例性的凝胶耦合器构件被配置为保持透镜几何形状。 在本发明的一个方面，凝胶偶联剂包含水，甘油和聚乙烯醇，并且与现有技术相比表现出增加的干燥时间和保存期限。 探头可以包括各种探头和/或换能器构造。 在示例性实施例中，探针将聚焦的，未聚焦的和/或散焦的超声能量传递到感兴趣的区域。 可以与本发明预期的超声系统可以联接和/或共同成像和/或监视。

公开(公告)号：US20140180174A1

公开(公告)日：2014-06-26

申请号：US14192520

申请日：2014-02-27

Applicant: GUIDED THERAPY SYSTEMS, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe

IPC: A61N7/00

CPC classification number: A61N7/00 ,  A61B5/4869 ,  A61B8/0858 ,  A61B8/14 ,  A61B8/429 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/483 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/0008 ,  A61N2007/0052 ,  A61N2007/027 ,  B06B1/0607 ,  B06B1/0622 ,  G01S7/5208 ,  G01S15/8906 ,  G01S15/899 ,  G01S15/8993

Abstract: Methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.

Abstract translation: 用于非侵入性减脂的方法可以包括靶向皮肤表面下方的感兴趣区域，其含有脂肪并将超声能量输送到感兴趣区域。 超声能量在脂肪细胞上产生具有所述超声能量的热损伤。 病变可以在脂肪细胞的表面产生开口，这允许将流体排出脂肪细胞并通过开口。 另外，通过对脂肪细胞施加超声能量，将温度升高到43度〜49度，可以实现细胞凋亡，从而减少脂肪。

公开(公告)号：US20140142430A1

公开(公告)日：2014-05-22

申请号：US14164598

申请日：2014-01-27

Applicant: GUIDED THERAPY SYSTEMS, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin

IPC: A61N7/02 ,  A61B8/00

CPC classification number: A61N7/02 ,  A61B8/14 ,  A61B8/429 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0008 ,  G01S15/8906 ,  G01S15/8936

Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.

Abstract translation: 一种用于向包含真皮的下部和脂肪的近端突起的组织提供超声治疗的方法和系统。 一个实施例将超声波能量传递到该区域，从而产生热损伤并使脂肪的近端突出物凝结，从而消除了向真皮中的脂肪突起。 实施例还可以包括在治疗之前，之后或之中使用相同或单独的探针的超声成像构造。 此外，可以使用各种治疗水平的超声波来增加脂肪代谢的速度。 另外，超声的机械作用物理地破坏脂肪细胞簇并延伸纤维结合。 机械作用也会增强淋巴引流，刺激排出脂肪衰变产物。

公开(公告)号：US08690779B2

公开(公告)日：2014-04-08

申请号：US13924355

申请日：2013-06-21

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

IPC: A61B7/02

CPC classification number: A61N7/00 ,  A61B8/085 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4444 ,  A61B8/4494 ,  A61B8/546 ,  A61N7/02

Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

Abstract translation: 公开了用于非侵入性组织紧固的系统和方法。 描述了诸如表面肌腱膜系统（SMAS）组织，肌肉，脂肪组织，真皮组织及其组合的组织的热处理。 在一个方面，一种系统被配置用于通过在深度，分布，温度和能量水平传递超声能量来治疗组织，以实现期望的美容效果。

公开(公告)号：US08690778B2

公开(公告)日：2014-04-08

申请号：US13924323

申请日：2013-06-21

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

IPC: A61B7/02

CPC classification number: A61N7/00 ,  A61B8/085 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4444 ,  A61B8/4494 ,  A61B8/546 ,  A61N7/02

Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

Abstract translation: 公开了用于非侵入性组织紧固的系统和方法。 描述了诸如表面肌腱膜系统（SMAS）组织，肌肉，脂肪组织，真皮组织及其组合的组织的热处理。 在一个方面，一种系统被配置用于通过在深度，分布，温度和能量水平传递超声能量来治疗组织以实现期望的美容效果。

公开(公告)号：US08636665B2

公开(公告)日：2014-01-28

申请号：US13789562

申请日：2013-03-07

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin

IPC: A61B8/00

CPC classification number: A61N7/02 ,  A61B8/14 ,  A61B8/429 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0008 ,  G01S15/8906 ,  G01S15/8936

Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.

Abstract translation: 一种用于向包含真皮的下部和脂肪的近端突起的组织提供超声治疗的方法和系统。 一个实施例将超声波能量传递到该区域，从而产生热损伤并使脂肪的近端突出物凝结，从而消除了向真皮中的脂肪突起。 实施例还可以包括在治疗之前，之后或之中使用相同或单独的探针的超声成像构造。 此外，可以使用各种治疗水平的超声波来增加脂肪代谢的速度。 另外，超声的机械作用物理地破坏脂肪细胞簇并延伸纤维结合。 机械作用也会增强淋巴引流，刺激排出脂肪衰变产物。

公开(公告)号：US20130211258A1

公开(公告)日：2013-08-15

申请号：US13835635

申请日：2013-03-15

Applicant: Guided Therapy Systems, LLC

Inventor： PETER G. BARTHE ,  MICHAEL H. SLAYTON ,  INDER RAJ S. MAKIN

IPC: A61N7/02 ,  A61B8/13 ,  A61B8/00 ,  A61B8/08

CPC classification number: A61N7/02 ,  A61B5/7405 ,  A61B8/08 ,  A61B8/0858 ,  A61B8/13 ,  A61B8/14 ,  A61B8/4281 ,  A61B8/4444 ,  A61B8/4461 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/469 ,  A61B2090/378 ,  A61B2562/046 ,  A61N2007/0008 ,  A61N2007/0034 ,  A61N2007/0052 ,  A61N2007/0078 ,  A61N2007/0082 ,  A61N2007/027

Abstract: Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue on a face and/or neck are described.

公开(公告)号：US20130012755A1

公开(公告)日：2013-01-10

申请号：US13545953

申请日：2012-07-10

Applicant: Michael H. Slayton

Inventor： Michael H. Slayton

IPC: A61N7/00 ,  A61F2/12 ,  A61N2/00 ,  A61M37/00 ,  A61N5/10

CPC classification number: A61N7/00 ,  A61B18/18 ,  A61B2018/00642 ,  A61M37/0092 ,  A61N7/02 ,  A61N2007/0004 ,  A61N2007/0017 ,  A61N2007/0034 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/006 ,  A61N2007/0073 ,  A61N2007/0078 ,  A61N2007/027

Abstract: Various embodiments provide methods and systems for ultrasound treatment of tissue are provided. Accordingly, a method can include locating an implant in a site in a body, directing a medicant to at least one of the implant and the site, directing ultrasound energy to the site, and accelerating healing of the implant and/or native tissue at the site.

Abstract translation: 提供了各种实施例提供了用于组织超声处理的方法和系统。 因此，一种方法可以包括将植入物定位在体内的部位中，将药物定向到至少一个植入物和位点，将超声能量引导到部位，以及加速植入物和/或天然组织的愈合 现场。

公开(公告)号：US20120330222A1

公开(公告)日：2012-12-27

申请号：US13603159

申请日：2012-09-04

Applicant: Inder Raj S. Makin ,  Peter G. Barthe ,  Michael H. Slayton

Inventor： Inder Raj S. Makin ,  Peter G. Barthe ,  Michael H. Slayton

IPC: A61B18/04 ,  A61M37/00

CPC classification number: A61N7/02 ,  A61B8/4281 ,  A61B17/320068 ,  A61B2018/00005 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: Methods for ultrasound treatment of hyperhidrosis are provided. Various methods and systems for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, thermal and/or ablative energy can be deposited at the particular depth at which the sweat gland population is located below the skin surface. Ultrasound and non-ultrasound treatments for hyperhidrosis are provided.

Abstract translation: 提供超声治疗多汗症的方法。 用于针对性治疗汗腺的各种方法和系统可以以各种方式配置，例如仅通过使用治疗，治疗和监测，成像和治疗，或治疗，成像和监测，和/或通过使用集中的，未聚焦的 ，或通过控制各种空间和时间参数来散焦超声波。 结果，热汗和/或烧蚀能量可以沉积在汗腺群体位于皮肤表面下方的特定深度处。 提供超声和非超声治疗多汗症。

公开(公告)号：US20120197120A1

公开(公告)日：2012-08-02

申请号：US13444485

申请日：2012-04-11

Applicant: Inder Raj S. Makin ,  Peter G. Barthe ,  Michael H. Slayton

Inventor： Inder Raj S. Makin ,  Peter G. Barthe ,  Michael H. Slayton

IPC: A61M37/00 ,  A61B8/00

CPC classification number: A61N7/02 ,  A61B8/4281 ,  A61B17/320068 ,  A61B2018/00005 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: A method and system for ultrasound treatment of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.

Abstract translation: 提供了一种用于汗腺超声处理的方法和系统。 用于针对性治疗汗腺的示例性方法和系统可以以各种方式配置，例如仅通过使用治疗，治疗和监测，成像和治疗，或治疗，成像和监测，和/或通过使用聚焦， 通过控制各种空间和时间参数，不聚焦或散焦超声波。 因此，可以在异常汗腺群体位于皮肤表面下方的特定深度沉积烧蚀能量。