公开(公告)号：US20220390369A1

公开(公告)日：2022-12-08

申请号：US17765364

申请日：2020-09-30

Applicant: The Regents of the University of Colorado, a body corporate ,  Sorbonne Université

Inventor： Rafael Piestun ,  Kristina Irsch ,  Simon Labouesse ,  Sylvain Gigan

IPC: G01N21/47 ,  A61B5/00 ,  G01N21/64

Abstract: Systems and methods are provided for imaging and characterizing objects including the eye using non-uniform or speckle illumination patterns. According to the present technology, a method for characterizing at least a portion of an object may include generating, using at least one light source, one or multiple non-uniform illumination patterns on an object. The method may also include detecting, using a detector, backscattered light from the object in response to the generating. The method may further include extracting, using the detector, data representative of the backscattered light. The method may also include processing, using a processing unit, the data representative of the backscattered light to create one or more images of at least a portion of the object.

公开(公告)号：US20210320808A1

公开(公告)日：2021-10-14

申请号：US17230892

申请日：2021-04-14

Applicant: The Regents of the University of Colorado, a body corporate

Inventor： Rafael Piestun ,  Haiyan Wang

IPC: H04L9/38 ,  G02B27/42

Abstract: Systems and methods for azimuthal multiplexing using three-dimensional diffractive optics An azimuthal optical multiplexing system includes a light source. The system includes two or more at least partially transparent plates. Each plate of the two or more plates has a structured or patterned surface positioned in an optical path of the light source. The system includes means for rotating at least one plate of the two or more plates axially with respect to at least one other plate of the two or more plates. The means for rotating is operatively coupled to the at least one plate. The structured or patterned surface is configured to modulate light directed along the optical path and through the two or more plates.

公开(公告)号：US10254534B2

公开(公告)日：2019-04-09

申请号：US15365813

申请日：2016-11-30

Applicant: The Regents of the University of Colorado, a body corporate

Inventor： Antonio Miguel Caravaca-Aguirre ,  Rafael Piestun

IPC: G02B23/24 ,  G02B23/26 ,  G02B6/02 ,  H04N5/247 ,  H04N5/225 ,  G02B6/028

Abstract: An example multimode fiber endoscope may include an elongated body having a proximal end and a distal end; a multimode fiber disposed within the elongated body and extending from the proximal end to the distal end of the elongated body; a light source disposed relative to the proximal end of the elongated body; a light detector disposed relative to the proximal end of the elongated body; and multiple optical elements disposed between the light source and the multimode fiber. One or more of the optical elements are configured to direct light from the light source into the multimode fiber. One or more of the optical elements are configured to direct light from the multimode fiber to the detector. In some embodiments, the multimode fiber may be a single multimode fiber.

公开(公告)号：US20180268185A1

公开(公告)日：2018-09-20

申请号：US15856539

申请日：2017-12-28

Applicant: The Regents of the University of Colorado, a body Corporate.

Inventor： Rafael Piestun ,  Anthony Barsic

IPC: G06K9/00 ,  G06T7/73 ,  G02B21/36 ,  G06K9/68 ,  G01N21/64 ,  G02B21/14

CPC classification number: G06K9/00 ,  G01N21/6458 ,  G02B21/14 ,  G02B21/361 ,  G02B21/367 ,  G06K9/6807 ,  G06T7/73 ,  G06T2200/04 ,  G06T2207/10016 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30242 ,  H05K999/99

Abstract: Systems, methods, and computer program products are disclosed to localize and/or image a dense array of particles. In some embodiments, a plurality of particles may be imaged using an imaging device. A plurality of point spread function dictionary coefficients of the image may be estimated using a point spread function dictionary; where the point spread function dictionary can include a plurality of spread function responses corresponding to different particle positions. From the point spread function dictionary coefficients the number of particles in the image can be determined. Moreover location of each particle in the image can be determined from the point spread function dictionary coefficients.

公开(公告)号：US20160125610A1

公开(公告)日：2016-05-05

申请号：US14934031

申请日：2015-11-05

Applicant: The Regents of the University of Colorado, a body corporate

Inventor： Rafael Piestun

IPC: G06T7/00 ,  H04N13/02 ,  G06T1/20

CPC classification number: H04N13/204 ,  G06T2200/04 ,  H04N5/23212 ,  H04N13/254

Abstract: Imaging systems and imaging methods are disclosed to estimate a three-dimensional position of an object at a scene and/or generate a three-dimensional image of the scene. The imaging system may include, for example, one or many light sources; an optical system configured to direct light from the one or more light sources into a pattern onto the scene; a mask; a detector array disposed to receive light from the scene through the mask; and at least one processor communicatively coupled with the detector and configured to estimate a depth of a particle within the scene.

Abstract translation: 公开了成像系统和成像方法来估计物体在场景的三维位置和/或生成场景的三维图像。 成像系统可以包括例如一个或多个光源; 光学系统，被配置为将来自所述一个或多个光源的光引导到所述场景上的图案中; 面具 检测器阵列，被设置成通过所述掩模接收来自所述场景的光; 以及至少一个处理器，其与所述检测器通信地耦合并且被配置为估计所述场景内的粒子的深度。