公开(公告)号：US20060040344A1

公开(公告)日：2006-02-23

申请号：US10540370

申请日：2004-06-21

Applicant: Michael White ,  Doris Beck ,  Ivan Gilbert

Inventor： Michael White ,  Doris Beck ,  Ivan Gilbert

IPC: C12P33/06

CPC classification number: C12P33/02 ,  C07J1/00

Abstract: The present invention relates to a two part microbial process for the preparation of 7-oxo-5-androstene steroids of Formula III.

Abstract translation: 本发明涉及用于制备式III的7-氧代-5-雄甾烯类固醇的两部分微生物方法。

公开(公告)号：US06893016B2

公开(公告)日：2005-05-17

申请号：US10177698

申请日：2002-06-21

Applicant: Darrell E. Pav ,  Randy R. Seidel ,  Michael White

Inventor： Darrell E. Pav ,  Randy R. Seidel ,  Michael White

IPC: B41J2/01 ,  B41J2/44 ,  B41J3/407 ,  B42C1/10 ,  B65H5/02 ,  B65H5/06 ,  B65H5/08 ,  B65H5/16 ,  B65H29/60 ,  B65H39/055 ,  B65H39/115 ,  B65H5/34

CPC classification number: B42C1/10 ,  B65H39/055 ,  B65H2301/16 ,  B65H2301/4311 ,  B65H2301/432 ,  B65H2301/5111 ,  B65H2511/414 ,  B65H2220/01

Abstract: A combined insert feeder and printer is employed such that blank inserts are stored in its hopper. The blank inserts are then fed by a transporter to a printer. The printer prints onto the insert to create a printed insert which is transported into a moving pocket.

Abstract translation: 使用组合的插入式进料器和打印机，使得坯料插入物储存在其料斗中。 然后将空白插入物由运送器送入打印机。 打印机打印到插入物上以产生被输送到移动口袋中的印刷插件。

公开(公告)号：US20050031705A1

公开(公告)日：2005-02-10

申请号：US10633945

申请日：2003-08-04

Applicant: Michael Tyndall ,  John Cunningham ,  Michael White

Inventor： Michael Tyndall ,  John Cunningham ,  Michael White

IPC: A61K9/00 ,  A61K31/185 ,  A61K31/19 ,  A61K31/685 ,  A61K33/18 ,  A61K33/36 ,  A61K33/40

CPC classification number: A61K9/0017 ,  A61K31/185 ,  A61K31/19 ,  A61K31/685 ,  A61K33/18

Abstract: The present invention provides compositions and methods for the treatment of infection in a subject. More particularly, the invention provides a therapy for the treatment or prevention of mammary infections, such as bovine mastitis, comprising the topical administration to a subject of an anti-microbial agent and a phospholipid-containing skin conditioner.

Abstract translation: 本发明提供用于治疗受试者感染的组合物和方法。 更具体地，本发明提供了一种用于治疗或预防乳腺感染的治疗剂，例如牛乳腺炎，包括对受试者的抗微生物剂和含磷脂皮肤调理剂的局部给药。

公开(公告)号：US10911900B1

公开(公告)日：2021-02-02

申请号：US16553849

申请日：2019-08-28

Applicant: Michael White

Inventor： Michael White

IPC: G08B21/02 ,  H04W4/029 ,  G06F3/14 ,  G08B7/06 ,  H04W4/02 ,  H04B1/3827 ,  G06F3/02

Abstract: A multiple object location assembly includes a tracking unit that is wearable on a user. The tracking unit has a plurality of communication channels that is each programmable to have a distance alarm is set to a pre-determined trigger distance. A plurality of transmitting units is provided and each of the transmitting units broadcasts a tracking signal to the tracking unit. each of the transmitting units is coupled to a respective one of a plurality of objects and the tracking signal broadcast by each of the transmitting units is associated with the respective object. Each of the transmitting units is assigned to a respective one of the communication channels in the tracking unit. Moreover, the distance alarm in a respective one of the communication channels is turned on when the transmitter assigned to the respective communication channel moves beyond the pre-determined trigger distance from the tracking unit.

公开(公告)号：US09522580B2

公开(公告)日：2016-12-20

申请号：US13369020

申请日：2012-02-08

Applicant: Michael White ,  Robert Jensen ,  Larry Betcher

Inventor： Michael White ,  Robert Jensen ,  Larry Betcher

IPC: B60C25/04 ,  B60C25/02

CPC classification number: B60C25/02

Abstract: A tire spoon may be provided. The tire spoon may include: a bar; and a spoon portion at one end of the bar, the spoon portion having two outer side edges and a middle portion located between the two outer side edges, and at a given cross section of the spoon portion, the middle portion cross sectional thickness is greater than a cross sectional thickness of the two outer side edges. A method of forming a tire spoon is provided. The method may include: providing a spoon portion on an end of a bar; and forming the spoon portion to have middle section that has a thicker cross section than either side portion of the spoon portion.

Abstract translation: 可以提供轮胎勺子。 轮胎勺子可以包括：一个酒吧; 勺子部分具有两个外侧边缘和位于两个外侧边缘之间的中间部分，并且在勺部分的给定横截面处，中间部分横截面厚度更大 比两个外侧边缘的横截面厚度。 提供一种形成轮胎勺子的方法。 该方法可以包括：在棒的端部提供勺子部分; 并且形成所述勺子部分以具有比所述勺子部分的任一侧部分具有更厚横截面的中间部分。

公开(公告)号：US09481497B1

公开(公告)日：2016-11-01

申请号：US14564051

申请日：2014-12-08

Applicant: Michael White

Inventor： Michael White

IPC: B65D51/32 ,  B05C11/11 ,  A45D40/26 ,  A46B3/12

CPC classification number: B65D51/32 ,  A45D40/265 ,  A46B3/12 ,  A46B11/001 ,  B05C11/11 ,  B65D1/14

Abstract: A solution storage and application system includes a bottle and an applicator assembly constructed to mutually engage for safe storage and transport of any desired solution within the bottle. The applicator assembly includes a handle by which the applicator assembly is to be manipulated, the handle extending from a free end to a circular flange that serves as a cap for closure of the interior of the bottle when the applicator assembly engages the bottle. A ferrule extends from the flange away from the handle and retains an applicator that extends from the ferrule away from the handle such that longitudinal ends of the handle and applicator serve as longitudinal ends of the applicator assembly.

Abstract translation: 解决方案存储和应用系统包括瓶子和施用器组件，其构造成相互接合以便安全地存储和运输瓶子内的任何所需的溶液。 施用器组件包括手柄，通过该把手，施用器组件将被操纵，手柄从自由端延伸到圆形凸缘，当施用器组件接合瓶时，其用作封闭瓶子内部的盖。 套圈从凸缘延伸离开手柄并且保持从套圈延伸远离手柄的施加器，使得手柄和施用器的纵向端部用作施用器组件的纵向端部。

公开(公告)号：US20160186088A1

公开(公告)日：2016-06-30

申请号：US14978000

申请日：2015-12-22

Applicant: Michael White ,  Xinhua Li ,  Joseph McLellan ,  Olivier Schueller ,  Patrick Reust ,  Alan M. Schilowitz ,  David J. Baillargeon

Inventor： Michael White ,  Xinhua Li ,  Joseph McLellan ,  Olivier Schueller ,  Patrick Reust ,  Alan M. Schilowitz ,  David J. Baillargeon

IPC: C10M141/02 ,  C10M137/10 ,  C10M169/04 ,  C10M125/10 ,  C10M129/40

CPC classification number: C10M125/26 ,  C10M103/06 ,  C10M125/10 ,  C10M129/40 ,  C10M133/06 ,  C10M137/10 ,  C10M137/12 ,  C10M141/02 ,  C10M141/06 ,  C10M141/10 ,  C10M169/04 ,  C10M2201/062 ,  C10M2201/14 ,  C10M2205/0285 ,  C10M2207/125 ,  C10M2207/126 ,  C10M2207/16 ,  C10M2207/262 ,  C10M2215/04 ,  C10M2219/046 ,  C10M2223/045 ,  C10M2223/06 ,  C10N2210/02 ,  C10N2230/06 ,  C10N2230/40 ,  C10N2230/42 ,  C10N2230/43 ,  C10N2230/50 ,  C10N2230/70 ,  C10N2240/10 ,  C10N2250/16

Abstract: A method for improving wear control in an engine or other mechanical component lubricated with a lubricating oil by using as the lubricating oil a formulated oil. The formulated oil has a composition including a lubricating oil base stock as a major component, and encapsulated microscale particles, as a minor component. The minor component contains no sulfur or phosphorus. The encapsulated microscale particles include an encapsulating material and a core material encapsulated by the encapsulating material. The core material includes at least one metal salt selected from a metal oxide, metal hydroxide, metal carbonate, or mixtures thereof. The encapsulating material is derived from a carboxylic acid selected from an aliphatic carboxylic acid, a cycloaliphatic carboxylic acid, an aromatic carboxylic acid, and mixtures thereof. The lubricating oils are useful in internal combustion engines.

Abstract translation: 一种用于通过使用配制的油作为润滑油来改善用润滑油润滑的发动机或其它机械部件中的磨损控制的方法。 所配制的油具有作为主要成分的润滑油原料作为次要成分的包封微粒子的成分。 次要组分不含硫或磷。 封装的微粒子包括封装材料和由封装材料包封的芯材料。 核心材料包括至少一种选自金属氧化物，金属氢氧化物，金属碳酸盐或其混合物的金属盐。 封装材料衍生自选自脂族羧酸，脂环族羧酸，芳族羧酸及其混合物的羧酸。 润滑油可用于内燃机。

公开(公告)号：US09035030B2

公开(公告)日：2015-05-19

申请号：US13401559

申请日：2012-02-21

Applicant: Jochen Salfeld ,  Michael Roguska ,  Michael Paskind ,  Subhashis Banerjee ,  Daniel Tracey ,  Michael White ,  Zehra Kaymakcalan ,  Boris Labkovsky ,  Paul Sakorafas ,  Geertruida M. Veldman ,  Amy Venturini ,  Angela Widom ,  Stuart Friedrich ,  Nicholas W. Warne ,  Angela Myles ,  John Gawain Elvin ,  Alexander Robert Duncan ,  Elaine Joy Derbyshire ,  Sara Carmen ,  Stephen Smith ,  Thor Las Holtet ,  Sarah Leila Du Fou

Inventor： Jochen Salfeld ,  Michael Roguska ,  Michael Paskind ,  Subhashis Banerjee ,  Daniel Tracey ,  Michael White ,  Zehra Kaymakcalan ,  Boris Labkovsky ,  Paul Sakorafas ,  Geertruida M. Veldman ,  Amy Venturini ,  Angela Widom ,  Stuart Friedrich ,  Nicholas W. Warne ,  Angela Myles ,  John Gawain Elvin ,  Alexander Robert Duncan ,  Elaine Joy Derbyshire ,  Sara Carmen ,  Stephen Smith ,  Thor Las Holtet ,  Sarah Leila Du Fou

IPC: C07K16/24 ,  C12P21/08 ,  A61K39/395 ,  A61K39/00 ,  C07K16/18 ,  C07K16/00 ,  C07K14/54 ,  A61K38/20

CPC classification number: C07K16/244 ,  A61K9/0019 ,  A61K38/208 ,  A61K39/00 ,  A61K39/3955 ,  A61K39/39591 ,  A61K45/06 ,  A61K47/20 ,  A61K47/22 ,  A61K47/26 ,  A61K2039/505 ,  C07K14/5434 ,  C07K16/00 ,  C07K16/18 ,  C07K2317/21 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/94 ,  Y10S514/863 ,  Y10S514/885 ,  Y10S514/886

Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Abstract translation: 公开了特异性结合人白细胞介素-12（hIL-12）的人抗体，优选重组人抗体。 优选的抗体对hIL-12具有高亲和力，并在体外和体内中和hIL-12活性。 本发明的抗体可以是全长抗体或其抗原结合部分。 本发明的抗体或抗体部分可用于检测hIL-12和抑制hIL-12活性，例如在患有hIL-12活性有害的病症的人类受试者中。 用于表达本发明的重组人抗体的核酸，载体和宿主细胞以及合成重组人抗体的方法也包括在本发明中。

公开(公告)号：US08765918B2

公开(公告)日：2014-07-01

申请号：US13429104

申请日：2012-03-23

Applicant: Jochen G. Salfeld ,  Michael Roguska ,  Michael Paskind ,  Subhashis Banerjee ,  Daniel Edward Tracey ,  Michael White ,  Zehra Kaymakcalan ,  Boris Labkovsky ,  Paul Sakorafas ,  Geertruida M. Veldman ,  Amy Venturini ,  Angela Widom ,  Stuart Friedrich ,  Nicholas W. Warne ,  Angela Myles ,  John Gawain Elvin ,  Alexander Robert Duncan ,  Elaine Joy Derbyshire ,  Sara Carmen ,  Stephen Smith ,  Thor Las Holtet ,  Sarah Leila Du Fou

Inventor： Jochen G. Salfeld ,  Michael Roguska ,  Michael Paskind ,  Subhashis Banerjee ,  Daniel Edward Tracey ,  Michael White ,  Zehra Kaymakcalan ,  Boris Labkovsky ,  Paul Sakorafas ,  Geertruida M. Veldman ,  Amy Venturini ,  Angela Widom ,  Stuart Friedrich ,  Nicholas W. Warne ,  Angela Myles ,  John Gawain Elvin ,  Alexander Robert Duncan ,  Elaine Joy Derbyshire ,  Sara Carmen ,  Stephen Smith ,  Thor Las Holtet ,  Sarah Leila Du Fou

IPC: C07K16/24 ,  A61K39/395 ,  A61K38/00

CPC classification number: C07K16/244 ,  A61K9/0019 ,  A61K38/208 ,  A61K39/00 ,  A61K39/3955 ,  A61K39/39591 ,  A61K45/06 ,  A61K47/20 ,  A61K47/22 ,  A61K47/26 ,  A61K2039/505 ,  C07K14/5434 ,  C07K16/00 ,  C07K16/18 ,  C07K2317/21 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/94 ,  Y10S514/863 ,  Y10S514/885 ,  Y10S514/886

Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Abstract translation: 公开了特异性结合人白细胞介素-12（hIL-12）的人抗体，优选重组人抗体。 优选的抗体对hIL-12具有高亲和力，并在体外和体内中和hIL-12活性。 本发明的抗体可以是全长抗体或其抗原结合部分。 本发明的抗体或抗体部分可用于检测hIL-12和抑制hIL-12活性，例如在患有hIL-12活性有害的病症的人类受试者中。 用于表达本发明的重组人抗体的核酸，载体和宿主细胞以及合成重组人抗体的方法也包括在本发明中。

公开(公告)号：US20140169145A1

公开(公告)日：2014-06-19

申请号：US14235572

申请日：2011-10-25

Applicant: M. Scott Bunker ,  Michael White ,  Timothy A. Mccree ,  Keith J. Kuehn ,  Andrew James Phelan ,  John P. Franz

Inventor： M. Scott Bunker ,  Michael White ,  Timothy A. Mccree ,  Keith J. Kuehn ,  Andrew James Phelan ,  John P. Franz

IPC: G11B33/10

CPC classification number: G11B33/10 ,  G11B3/125 ,  G11B7/0945 ,  G11B11/10595

Abstract: A drive carrier includes a first computing device with light source control capacity and a light source proximate to a front plate of the drive carrier. The first computing device receives a signal from a second computing device (external to the drive carrier) and controls the light source proximate to the front plate of the drive carrier based on the signal.

Abstract translation: 驱动载体包括具有光源控制能力的第一计算装置和靠近驱动载体的前板的光源。 第一计算设备从第二计算设备（在驱动器载体的外部）接收信号，并且基于该信号控制靠近驱动器载体的前板的光源。