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公开(公告)号：US20180265908A1
公开(公告)日：2018-09-20
申请号：US15760348
申请日：2016-06-22
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Tadashi FUKAMI , Hidenao YAMADA
CPC classification number: C12Q1/04 , C12M41/38 , G01N15/1434 , G01N15/1468 , G01N21/41 , G01N21/45 , G01N33/5073 , G01N2015/1006 , G01N2015/1454 , G01N2201/063 , G01N2400/00 , G02B21/00 , G02B21/361 , G02B21/365
Abstract: The present invention relates to a cell determination method for determining a cell type based on a content of glycogen in a cell, including: an acquisition step of acquiring optical path length data by measuring an optical path length of the cell; a calculation step of calculating an optical path length indicator correlated with the optical path length of the cell from the obtained optical path length data; a comparison step of comparing the calculated optical path length indicator with a threshold; and a determination step of determining whether the cell is a cell type having a high glycogen content in the cell or a cell type having a low glycogen content in the cell, based on the comparison result.
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公开(公告)号：US20180017371A1
公开(公告)日：2018-01-18
申请号：US15546168
申请日：2015-12-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Toyohiko YAMAUCHI , Hidenao YAMADA
CPC classification number: G01B9/0203 , G01B9/02015 , G01B9/02042 , G01B9/02049 , G01N21/45 , G01N33/4833 , G02B21/00 , G02B21/06 , G02B21/361
Abstract: An interference observation apparatus includes a light source which outputs incoherent light, a beam splitter, a sample holding table, an objective lens, a reference mirror, a lens, an aberration correction plate, a piezo element, a tube lens, a beam splitter, an imaging unit, a photodetector, an image acquisition unit, and a control unit. The control unit obtains an interference intensity of combined light on the basis of a detection signal output from the photodetector, and adjusts an interference optical system to increase the interference intensity.
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