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公开(公告)号：US20160082120A1
公开(公告)日：2016-03-24
申请号：US14863125
申请日：2015-09-23
Applicant: Genentech, Inc.
Inventor： Andrew Polson , Shang-Fan Yu , Yu-Waye Chu , Michael Wenger
IPC: A61K47/48 , A61K31/4184 , A61K39/395
CPC classification number: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K16/2803 , C07K16/2887 , C07K16/3061 , C07K2317/24
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
Abstract translation: 本文提供了使用包含抗CD79b抗体与附加治疗剂组合的免疫缀合物来治疗特别是滤泡性淋巴瘤和/或弥漫性大B细胞淋巴瘤的B细胞增殖性疾病的方法。
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公开(公告)号：US20140127197A1
公开(公告)日：2014-05-08
申请号：US13760751
申请日：2013-02-06
Applicant: GENENTECH, INC.
Inventor： Allen J. Ebens , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
IPC: C07K16/30 , A61K45/06 , A61K39/395
CPC classification number: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号：US20140030281A1
公开(公告)日：2014-01-30
申请号：US13936284
申请日：2013-07-08
Applicant: Genentech, Inc.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , Bing Zheng
IPC: A61K47/48 , A61K45/06 , A61K31/706
CPC classification number: A61K47/6807 , A61K31/706 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867
Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD22抗体和免疫缀合物及其使用方法。
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