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    SELF-HEATING SYSTEMS AND METHODS FOR RAPIDLY HEATING A COMESTIBLE SUBSTANCE
    22.
    发明申请
    SELF-HEATING SYSTEMS AND METHODS FOR RAPIDLY HEATING A COMESTIBLE SUBSTANCE 有权
    自助加热系统和方法快速加热可触及的物质

    公开(公告)号：US20100227027A1

    公开(公告)日：2010-09-09

    申请号：US12400730

    申请日：2009-03-09

    申请人： John Ford ,  Douglas Lund

    发明人： John Ford ,  Douglas Lund

    IPC分类号： B65D81/34 ,  B65B3/04

    CPC分类号： F24V30/00 ,  A47J36/28 ,  B23P11/00 ,  B65D81/3484 ,  C09K5/18 ,  Y10T29/49826

    摘要： Self-heating containers comprise a reaction chamber and a heating chamber. The heating chamber is sized to contain a substance to be heated. The reaction chamber contains reactants which, when contacted, exothermically react. The reaction chamber is divided into a first compartment and a second compartment with a barrier therebetween. The barrier comprises a first barrier portion and a second barrier portion. The first barrier portion is attached to a reaction chamber wall and has an opening sized to allow reactants to flow through from one compartment to the other. The second barrier portion is attached to the first barrier portion to close the opening. The barrier can be opened by moving an actuator into engagement with the second barrier portion to dislodge the second barrier portion from the first barrier portion and thereby open the barrier.

    摘要翻译： 自加热容器包括反应室和加热室。 加热室的大小适于容纳待加热物质。 反应室含有当接触时放热反应的反应物。 反应室被分成第一隔室和第二隔室，隔室之间具有阻挡层。 阻挡层包括第一阻挡部分和第二阻挡部分。 第一阻挡部分连接到反应室壁上，并且具有一定尺寸以允许反应物从一个隔室流过另一隔室的开口。 第二阻挡部分附接到第一阻挡部分以封闭开口。 可以通过将致动器移动到与第二阻挡部分接合以将第二阻挡部分从第一阻挡部分移开并从而打开阻挡物来打开阻挡物。

    Thieno[2,3-B] pyridines as potassium channel inhibitors
    24.
    发明授权
    Thieno[2,3-B] pyridines as potassium channel inhibitors 失效
    噻吩并[2,3-B]吡啶作为钾通道抑制剂

    公开(公告)号：US07576212B2

    公开(公告)日：2009-08-18

    申请号：US11297330

    申请日：2005-12-09

    申请人： John Ford ,  Nicholas John Palmer ,  John Frederick Atherall ,  David John Madge ,  Derek John

    发明人： John Ford ,  Nicholas John Palmer ,  John Frederick Atherall ,  David John Madge ,  Derek John

    IPC分类号： C07D513/02

    CPC分类号： C07D495/04 ,  C07D333/36 ,  C07D333/38 ,  C07D409/12

    摘要： The invention provides compounds of the formula: wherein R1 is aryl, heteroaryl, cycloalkyl or alkyl; R2 is H, alkyl, nitro, CO2R7, CONR5R6 or halo; R3 and R4 are H, NR5R6, NC(O)R7, halo, trifluromethyl, alkyl, CONR5R6, CO2R7, nitrile or alkoxy; R5 and R6 may be the same or different and may be H, alkyl, aryl, heteroaryl or cycloalkyl; or R5 and R6 may together form a saturated, unsaturated or partially saturated 4 to 7 member ring, wherein said ring may optionally comprise one or more further heteroatoms selected from N, O or S; R7 is H or alkyl; A is H, halo, or a group of formula X-L-Y; X is O, S or NR8; R8 is H or alkyl; L is (CH2)n, where n is 0, 1, 2, 3 or 4; and Y is aryl, a heterocyclic group, alkyl, alkenyl or cycloalkyl; the products of mono- and di-oxidation of sulphur and/or mono-oxidation of nitrogen moieties in compounds of formula I; or a pharmaceutically acceptable salt thereof. These compounds find use as inhibitors of potassium ion channels and thus are useful in the treatment of various conditions including arrhythmia and type-2 diabetes mellitus.

    摘要翻译： 本发明提供下式的化合物：其中R1是芳基，杂芳基，环烷基或烷基; R2是H，烷基，硝基，CO 2 R 7，CONR 5 R 6或卤素; R3和R4是H，NR5R6，NC（O）R7，卤素，三氟甲基，烷基，CONR5R6，CO2R7，腈或烷氧基; R5和R6可以相同或不同，可以是H，烷基，芳基，杂芳基或环烷基; 或R 5和R 6可以一起形成饱和的，不饱和的或部分饱和的4至7元环，其中所述环可任选地包含一个或多个选自N，O或S的其它杂原子; R7是H或烷基; A是H，卤素或式X-L-Y基团; X是O，S或NR8; R8是H或烷基; L是（CH 2）n，其中n是0,1,2,3或4; Y为芳基，杂环基，烷基，链烯基或环烷基; 式I化合物中硫的单和二氧化和/或氮部分的单氧化的产物; 或其药学上可接受的盐。 这些化合物可用作钾离子通道的抑制剂，因此可用于治疗各种病症，包括心律失常和2型糖尿病。

    VEHICLE ENGINE REMOVAL SYSTEM
    26.
    发明申请
    VEHICLE ENGINE REMOVAL SYSTEM 审中-公开
    车用发动机拆卸系统

    公开(公告)号：US20080105638A1

    公开(公告)日：2008-05-08

    申请号：US11936196

    申请日：2007-11-07

    申请人： John F. Crawford ,  John Ford ,  Adam C. Hunt ,  Benjamin A. Sternberg

    发明人： John F. Crawford ,  John Ford ,  Adam C. Hunt ,  Benjamin A. Sternberg

    IPC分类号： B66C23/44

    CPC分类号： B66C1/62 ,  B25H1/0007 ,  B25H5/00 ,  B66C1/107

    摘要： An engine and transmission removal system which includes an engine mount, a hoist mount, an engine framework, a lift mechanism, and a manual actuator. The engine mount includes a structural element for attachment to a part, such as an engine a transmission or a battery, in a vehicle drive system and shaped to conform to a portion of the part and having an extension to provide an additional lifting point when removing or installing such part in a vehicle. These parts can be used in combination together, or in various combination of only some of these parts.

    摘要翻译： 发动机和变速器移除系统，其包括发动机支架，起重机架，发动机框架，升降机构和手动致动器。 发动机支架包括用于附接到车辆驱动系统中的诸如发动机或发动机的部件的结构元件，并且成形为符合部件的一部分并且具有延伸部以在移除时提供额外的提升点 或将这样的部件安装在车辆中。 这些部件可以组合使用，或者仅以这些部件中的一些的各种组合的形式使用。

    Modular magnetic fixture system
    27.
    发明申请
    Modular magnetic fixture system 审中-公开
    模块化磁夹具系统

    公开(公告)号：US20070241071A1

    公开(公告)日：2007-10-18

    申请号：US11810853

    申请日：2007-06-07

    申请人： Dario Antonioni ,  John Ford

    发明人： Dario Antonioni ,  John Ford

    IPC分类号： A47F5/08

    CPC分类号： A47F5/0807

    摘要： A customizable modular magnetic wall system is provided for displaying items while allowing a user to aesthetically configure and tailor the system to the user's needs. The system includes a magnetic backing plate and at least one module. The module includes a base portion and a utility member. The base portion of the module is magnetically securable at a plurality of positions on the backing plate. In addition, the utility member projects outwardly from the base portion and is sized and configured to receive the item. The module may include a shelf, hooks, and other various devices for displaying the item.

    摘要翻译： 提供可定制的模块化磁壁系统，用于显示项目，同时允许用户根据用户的需要美观地配置和定制系统。 该系统包括磁性背板和至少一个模块。 模块包括基座部分和实用部件。 模块的基座部分在背板上的多个位置处是可磁性地固定的。 此外，实用部件从基部向外突出并且被设定和配置成接收该物品。 模块可以包括搁板，挂钩和用于显示该物品的其它各种装置。

    Compounds
    28.
    发明申请
    Compounds 有权
    化合物

    公开(公告)号：US20070161672A1

    公开(公告)日：2007-07-12

    申请号：US11635786

    申请日：2006-12-08

    申请人： John Ford ,  David Madge ,  Helen Payne ,  Jamie Knight

    发明人： John Ford ,  David Madge ,  Helen Payne ,  Jamie Knight

    IPC分类号： A61K31/4743 ,  C07D498/02

    CPC分类号： C07D495/04

    摘要： Thienopyridine compounds which are potassium channel inhibitors are described. Pharmaceutical compositions comprising the compounds and their use in the treatment or prevention of cancer, arrhythmias, autoimmune diseases and inflammatory diseases, including gastric cancer, atrial fibrillation, type-2 diabetes mellitus, rheumatoid arthritis, type-1 diabetes, inflammatory bowel disorder and demyelinating disorders such as multiple sclerosis are also disclosed.

    摘要翻译： 描述了作为钾通道抑制剂的噻吩并吡啶化合物。 包含该化合物的药物组合物及其在治疗或预防癌症，心律不齐，自身免疫性疾病和炎性疾病中的用途，包括胃癌，心房颤动，2型糖尿病，类风湿性关节炎，1型糖尿病，炎症性肠病和脱髓鞘 还公开了多发性硬化的病症。

    SELF-HEATING CONTAINER
    29.
    发明申请
    SELF-HEATING CONTAINER 审中-公开
    自助式集装箱

    公开(公告)号：US20070125362A1

    公开(公告)日：2007-06-07

    申请号：US11559873

    申请日：2006-11-14

    申请人： John Ford ,  Douglas Lund

    发明人： John Ford ,  Douglas Lund

    IPC分类号： F24J1/00

    CPC分类号： B65D81/3484 ,  B65D17/4011 ,  B65D2517/0016 ,  F24V30/00 ,  F25D5/02 ,  F25D2331/805

    摘要： Various embodiments of the present invention feature a self-heating or self-cooling container that is simple in design. The container includes an outer container body, an inner container body, a reactant vessel, a breakable barrier, and a breaking device. The outer container body defines a first chamber and includes a first reactant. The inner container body defines a second chamber. The inner container body is disposed within the first chamber and hold a substance to be heated or cooled. The reactant vessel is provided within the first chamber underneath the inner container body. The reactant vessel contains a second reactant capable of reacting with the first reactant to generate an exothermic or endothermic reaction. The breakable barrier covers the reactant vessel. The breaking device is disposed within the first chamber between the inner container body and the reactant vessel. The breaking device is capable of breaking the barrier to release the second reactant into the first chamber to mix and react with the first reactant when activated.

    摘要翻译： 本发明的各种实施例的特征在于设计简单的自加热或自冷容器。 容器包括外部容器主体，内部容器主体，反应物容器，可破坏的屏障和断开装置。 外部容器主体限定第一室并且包括第一反应物。 内容器主体限定第二腔室。 内部容器主体设置在第一室内并保持待加热或冷却的物质。 反应物容器设置在内容器主体下方的第一室内。 反应容器含有能够与第一反应物反应产生放热或吸热反应的第二反应物。 可破坏的屏障覆盖反应物容器。 破碎装置设置在内容器主体和反应容器之间的第一室内。 破碎装置能够破坏阻挡层，以将第二反应物释放到第一室中，以在被激活时与第一反应物混合并反应。