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    Fabricating An Implantable Medical Device From An Amorphous Or Very Low Crystallinity Polymer Construct
    22.
    发明申请
    Fabricating An Implantable Medical Device From An Amorphous Or Very Low Crystallinity Polymer Construct 有权
    从非晶或非常低结晶度聚合物构造制造植入式医疗器械

    公开(公告)号：US20100252965A1

    公开(公告)日：2010-10-07

    申请号：US12465570

    申请日：2009-05-13

    申请人： Yunbing Wang ,  Lothar W. Kleiner

    发明人： Yunbing Wang ,  Lothar W. Kleiner

    IPC分类号： B29C47/20 ,  B29C71/02

    CPC分类号： B29D23/00 ,  A61L31/06 ,  A61L31/14 ,  B29C71/0063 ,  C08L67/04

    摘要： Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity.

    摘要翻译： 本文公开了通过退火，成核剂或两者制造具有改善的断裂韧性的聚合物可植入装置的方法。 完全无定形或具有非常低的结晶度的聚合物构件被退火，没有或基本上没有晶体生长以增加成核密度。 或者，聚合物构造物包括成核剂。 通过增加温度，变形或两者，聚合物构造物的结晶度随着成核密度的增加而增加。 在结晶度增加之后，可以由聚合物构造体制造可植入的医疗装置，例如支架。

    STENTS FABRICATED FROM A SHEET WITH INCREASED STRENGTH, MODULUS AND FRACTURE TOUGHNESS
    23.
    发明申请
    STENTS FABRICATED FROM A SHEET WITH INCREASED STRENGTH, MODULUS AND FRACTURE TOUGHNESS 审中-公开
    具有增强强度，模量和断裂韧性的板材制成的STENTS

    公开(公告)号：US20100244304A1

    公开(公告)日：2010-09-30

    申请号：US12415841

    申请日：2009-03-31

    申请人： Yunbing Wang

    发明人： Yunbing Wang

    IPC分类号： B29C55/02 ,  B29C71/02

    CPC分类号： B29D23/001 ,  A61F2/92 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0031 ,  B23K2103/42 ,  B23K2103/50 ,  B29C53/40 ,  B29C55/04 ,  B29C2035/1658 ,  B29K2105/24 ,  B29K2995/006 ,  B29L2023/007

    摘要： Methods of fabricating a polymeric stent from a polymer sheet with improved strength, modulus and fracture toughness are disclosed. The methods include stretching the polymer sheet along one or more axesto increase the strength, fracture toughness, and modulus of the polymer along the axis of stretching. The methods further include forming a tubular stent from the stretched sheet. The stent can include a slide-and-lock mechanism that permits the stent to move from a collapsed diameter to an expanded diameter and inhibiting radial recoil from the expanded diameter.

    摘要翻译： 公开了从具有改进的强度，模量和断裂韧性的聚合物片制造聚合物支架的方法。 所述方法包括沿着一个或多个轴拉伸聚合物片材以提高聚合物沿着拉伸轴的强度，断裂韧性和模量。 所述方法还包括从拉伸的片材形成管状支架。 支架可以包括滑动和锁定机构，其允许支架从塌缩直径移动到扩张直径并且抑制从扩张直径的径向反冲。

    IMPLANTABLE MEDICAL DEVICES FABRICATED FROM POLYURETHANES WITH BIODEGRADABLE HARD AND SOFT BLOCKS AND BLENDS THEREOF
    24.
    发明申请
    IMPLANTABLE MEDICAL DEVICES FABRICATED FROM POLYURETHANES WITH BIODEGRADABLE HARD AND SOFT BLOCKS AND BLENDS THEREOF 有权
    具有可生物降解的硬块和软块的聚氨酯制成的可植入医疗器械及其混合物

    公开(公告)号：US20090182415A1

    公开(公告)日：2009-07-16

    申请号：US12014714

    申请日：2008-01-15

    申请人： YUNBING WANG

    发明人： YUNBING WANG

    IPC分类号： A61F2/82

    CPC分类号： A61L31/06 ,  A61L31/041 ,  Y10T428/1352 ,  C08L67/04

    摘要： Medical devices, such as stents, fabricated at least in part from a polymer composite including a biodegradable elastomeric phase dispersed within a biodegradable polymeric matrix are disclosed. The composite is composed of a polyurethane block copolymer including soft polymer blocks and a hard polymer blocks.

    摘要翻译： 公开了至少部分由包含分散在可生物降解的聚合物基体内的可生物降解的弹性体相的聚合物复合材料制成的医疗装置，例如支架。 复合材料由包含软聚合物嵌段和硬聚合物嵌段的聚氨酯嵌段共聚物组成。

    STENT FORMED FROM POLYMER-BIOCERAMIC COMPOSITE WITH RADIOPAQUE BIOCERAMIC PARTICLES
    25.
    发明申请
    STENT FORMED FROM POLYMER-BIOCERAMIC COMPOSITE WITH RADIOPAQUE BIOCERAMIC PARTICLES 有权
    从聚合物生物复合材料与无机生物颗粒形成的固体

    公开(公告)号：US20090171449A1

    公开(公告)日：2009-07-02

    申请号：US11968600

    申请日：2008-01-02

    申请人： YUNBING WANG

    发明人： YUNBING WANG

    IPC分类号： A61F2/86 ,  B29C47/00

    CPC分类号： A61L31/128 ,  A61L31/18

    摘要： Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in part of a radiopaque material having bioceramic particles with polymer chains grafted onto a surface of the bioceramic particles, the radiopaque functional groups being chemically bonded to the grafted polymer chains, are disclosed.

    摘要翻译： 公开了至少部分由具有接枝到生物陶瓷颗粒表面上的具有不透射线功能基团的生物陶瓷颗粒的聚合物 - 生物陶瓷复合材料制造的可植入医疗器械。 公开了至少部分不透射线材料制造的可植入医疗器械，其具有接枝在生物陶瓷颗粒表面上的具有生物陶瓷颗粒的聚合物链，不透射线的官能团与接枝的聚合物链化学键合。

    Method of Uniform Crimping and Expansion of Medical Devices
    29.
    发明申请
    Method of Uniform Crimping and Expansion of Medical Devices 有权
    医疗器械均匀压接和扩张方法

    公开(公告)号：US20140096357A1

    公开(公告)日：2014-04-10

    申请号：US13644347

    申请日：2012-10-04

    申请人： Yunbing Wang

    发明人： Yunbing Wang

    IPC分类号： B23P11/02

    CPC分类号： A61F2/958 ,  A61F2/91 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61M25/1025 ,  B23P11/00 ,  Y10T29/49863

    摘要： A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon, maintain a relatively uniform arrangement of balloon folds about the inner surface of the crimped scaffold so that the scaffold expands in a uniform manner when the balloon is inflated, and to avoid any possible over-stretching of balloon material.

    摘要翻译： 一种医疗装置 - 包括卷曲到具有膨胀气囊的导管的支架。 支架通过包括一个或多个气囊加压步骤的过程卷曲到气囊。 气囊加压步骤被选择以增强对球囊的支架保持，保持气囊折叠围绕卷曲框架的内表面的相对均匀的布置，使得当气囊膨胀时，支架以均匀的方式膨胀，并且避免任何可能的 气球材料过度伸展。