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21.发明申请公开(公告)号：US20220183982A1
公开(公告)日：2022-06-16
申请号：US17686827
申请日：2022-03-04
发明人： James R. Komorowski
IPC分类号： A61K9/24 , A61K45/06 , A23L33/15 , A61K9/00 , A61K31/155
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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22.发明申请公开(公告)号：US20220110873A1
公开(公告)日：2022-04-14
申请号：US17558763
申请日：2021-12-22
发明人： James R. Komorowski
IPC分类号： A61K9/24 , A61K45/06 , A23L33/15 , A61K9/00 , A61K31/155
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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公开(公告)号：US20210100776A1
公开(公告)日：2021-04-08
申请号：US16855966
申请日：2020-04-22
IPC分类号： A61K31/4188 , A61K9/28 , A61K9/20 , A61K8/19 , A61K8/67 , A61K9/00 , A61Q3/00 , A61Q5/00 , A61Q7/00
摘要： The present application relates to magnesium biotinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable biotin to mammals and treating or preventing symptoms of biotin deficiency.
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24.发明授权公开(公告)号：US10363222B2
公开(公告)日：2019-07-30
申请号：US15215979
申请日：2016-07-21
发明人： James R Komorowski
IPC分类号： A61K9/24 , A61K9/00 , A61K31/155 , A61K45/06 , A23L33/15
摘要： Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
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公开(公告)号：US20180110817A1
公开(公告)日：2018-04-26
申请号：US15654440
申请日：2017-07-19
IPC分类号： A61K36/31
CPC分类号： A61K36/31 , A23L2/00 , A61K9/0053 , A61K9/0095 , A61K9/1664
摘要： The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
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公开(公告)号：US20180098976A1
公开(公告)日：2018-04-12
申请号：US15730694
申请日：2017-10-11
IPC分类号： A61K31/4402 , A61K9/28
CPC分类号： A61K31/4402 , A61K9/28 , A61K9/2846 , A61K33/06
摘要： The present application relates to magnesium picolinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable magnesium to mammals and treating or preventing symptoms of magnesium deficiency.
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公开(公告)号：US20150320874A1
公开(公告)日：2015-11-12
申请号：US14805034
申请日：2015-07-21
发明人： James R. Komorowski
CPC分类号： A61K47/547 , A23L33/165 , A23V2002/00 , A61K31/00 , A61K31/28 , A61K31/4172 , A61K31/4402 , A61K31/445 , A61K33/24 , A61K47/545 , A61K2300/00 , A23V2250/1586
摘要： Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.
摘要翻译： 本文提供了用于施用铬的组合物，其包括至少两种组分：亲水性铬络合物和亲脂性铬络合物及其使用方法。 还提供了用于施用铬的组合物，其包括第一“快速作用”铬络合物和第二“慢效”铬络合物，其中第一铬络合物比慢效铬络合物更快地被吸收，以及方法 使用相同。 本文还提供了通过鉴定需要治疗，预防或改善与心脏代谢综合征有关的病症的受试者，并提供治疗有效量的组合物，其包括治疗，预防和改善与心脏代谢综合征相关的病症的方法 速效铬复合物和缓慢作用的铬络合物。
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公开(公告)号：US20150272991A1
公开(公告)日：2015-10-01
申请号：US14734618
申请日：2015-06-09
发明人： Vijaya Juturu , James R. Komorowski
IPC分类号： A61K33/24 , A61K31/555
CPC分类号： A61K33/24 , A61K31/415 , A61K31/4172 , A61K31/555
摘要： Provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising chromium and histidine, chromium histidinate complexes, or combinations thereof, to the individual.
摘要翻译： 本文提供了通过鉴定需要治疗，预防或改善与心脏代谢综合征有关的病症的受试者，并提供治疗有效量的包含铬和/或组合物的组合物来治疗，预防和改善与心脏代谢综合征相关的病症的方法 组氨酸，组氨酸复合物或其组合。
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公开(公告)号：US20230149499A1
公开(公告)日：2023-05-18
申请号：US17968788
申请日：2022-10-18
发明人： James R. Komorowski , Sarah Sylla
IPC分类号： A61K36/9066 , A61K31/26 , A61K36/82 , A61P15/12
CPC分类号： A61K36/9066 , A61K31/26 , A61K36/82 , A61P15/12
摘要： Disclosed herein are compositions for treating, ameliorating, preventing, or reducing the symptoms associated with menopause and/or hot flashes. The compositions disclosed herein comprise a curcumin composition, a green tea extract composition, and a phycocyanin composition that act as neurokinin 3 receptor antagonists. Also described herein are methods utilizing the aforementioned compositions.
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公开(公告)号：US20210338606A1
公开(公告)日：2021-11-04
申请号：US17373731
申请日：2021-07-12
发明人： James R. Komorowski
IPC分类号： A61K31/155 , A61K31/7004 , A61K33/00
摘要： The present invention generally relates to compositions and methods for topical or transdermal delivery, for promoting wound healing, reducing scarring, and/or promoting hair growth. Specifically, the present disclosure is directed to a topical arginine silicate formulation that demonstrates surprising improvements in promoting hair growth.
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