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公开(公告)号:US20240093243A1
公开(公告)日:2024-03-21
申请号:US18268894
申请日:2021-12-23
Inventor: Sangdun CHOI , Javaid NASIR
CPC classification number: C12N15/907 , C07K14/47 , C12N9/22 , C12N15/111 , C12N2310/20 , C12N2800/80
Abstract: A method for producing induced pluripotent stem cells by using CRISPR/Cas system is disclosed. The method includes a step of inserting a reprogramming factor by using a CRSPR/Cas system containing in a safe harbor of somatic cells a delivery means including two guides RNAs and a Cas protein-encoding nucleic acid. The method can prevent mutation in an off-target region and integrate a reprogramming factor into an on-target region safely and specifically, and regulates the reprogramming factor with doxycycline to guarantee consistent expression, whereby induced pluripotent stem cells can be effectively produced. In addition, the induced pluripotent stem cells produced by the method exhibit multipotent markers similar to those of human embryonic stem cells and can differentiate into derivatives of all the three germ layers.
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22.
公开(公告)号:US11933881B2
公开(公告)日:2024-03-19
申请号:US17445661
申请日:2021-08-23
Inventor: Jae Hyun Kim , Kyeongrok Kim
IPC: G01S13/90
CPC classification number: G01S13/90
Abstract: Disclosed are a method and apparatus for processing source data of a synthetic aperture radar in a satellite, including receiving source data generated based on a signal returned after an electronic device steers a beam from a synthetic aperture radar and backscatters, setting a plurality of subswaths after the electronic device parses the source data, storing based on the plurality of subswaths after the electronic device decodes the source data; and generating image data after the electronic device calls the decoded source data in the order of the plurality of subswaths.
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公开(公告)号:US20240034894A1
公开(公告)日:2024-02-01
申请号:US18265218
申请日:2021-11-02
Inventor: Moon Suk KIM , Joon Yeong PARK
Abstract: The present invention relates to a bio-ink composition for bio-printing comprising a polymer into which methacrylate is introduced, a crosslinking agent having 1-10 acrylate functional groups, and a photoinitiator; a method for preparing same; and a printing biological structure for controlling physical properties using same. The bio-ink composition for bio-printing prepared according to the present invention can be implanted in vivo and has a very high degree of biocompatibility or cell viability. In addition, the bio-ink composition of the present invention can be effectively utilized for bio-printing because a biological structure can be produced that is capable of controlling physical properties or in vivo application even when irradiated with light for a short period of time.
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24.
公开(公告)号:US11881021B2
公开(公告)日:2024-01-23
申请号:US18187353
申请日:2023-03-21
Inventor: Juyoung Kang , Sehyoung Kim , Seyeon Chun
CPC classification number: G06V20/188 , G06Q50/26
Abstract: Provided are a method of providing carbon emission management information, the method comprising extracting, by a carbon emission management information providing server, an area corresponding to a company to be evaluated from satellite image data of the company to be evaluated, calculating, by the carbon emission management information providing server, a greenhouse gas concentration of the area corresponding to the company to be evaluated from the satellite image data, calculating, by the carbon emission management information providing server, a change in vegetation index around the company to be evaluated from the satellite image data, analyzing, by the carbon emission management information providing server, a relationship between carbon emission management factors input in relation to the company to be evaluated, a change in the calculated greenhouse gas concentration, and the calculated change in vegetation index and generating, by the carbon emission management information providing server, carbon emission management information by using both a relationship between the carbon emission management factors and the change in the calculated greenhouse gas concentration and a relationship between the carbon emission management factors and the calculated change in vegetation index according to a result of the analyzing, and providing the generated carbon emission management information.
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公开(公告)号:US20240000608A1
公开(公告)日:2024-01-04
申请号:US18039074
申请日:2021-11-16
Inventor: Ji Man HONG
CPC classification number: A61F7/12 , F28F1/00 , A61F2007/006
Abstract: The present invention provides a nasopharyngeal airway management device for brain-nasal cavity cooling according to the present invention including a cooling gas induction hose that is a tubular body with a hollow inside along a length, and induces a cooling gas introduced through one side to the other side; an adapter that is connected to the other side of the cooling gas induction hose, is mounted around the patient's upper lip, distributes the cooling gas induced through the cooling gas induction hose to a pair of discharge ripples, and discharges the cooling gas; and a nasal cavity cooling tube that is a tubular body with a hollow inside along a length, one side is coupled to a discharge nipple of the adapter and the other side of which is inserted into the patient's nasal cavity, and forms a plurality of discharge holes for discharging the cooling gas to any one point of the length, so that the nasal cavity cooling tube that is connected to the adapter fixed to the patient's upper lip, and dividing and discharging the cooling gas introduced through the cooling gas induction hose is inserted into the nasopharynx through the patient's nostril, and the cooling gas (low-temperature oxygen) discharged through the discharge hole of the the nasal cavity cooling tube is discharged into the nasal cavity close to the brain, and thereby quick and easy stable local cooling of the brain is induced while maintaining the nasopharyngeal airway.
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公开(公告)号:US20230406295A1
公开(公告)日:2023-12-21
申请号:US18333840
申请日:2023-06-13
Applicant: Hyundai Motor Company , Kia Corporation , Ajou University Industry-Academic Cooperation Foundation
Inventor: Chan Jong Jang , Young Bin Min , Cheol Hwan Yun , Jong Sung Park , Bong Sob Song , Ji Min Lee , Sung Woo Lee
IPC: B60W30/09 , B60W30/095 , B60W60/00
CPC classification number: B60W30/09 , B60W30/0956 , B60W60/0015 , B60W2554/4041
Abstract: An embodiment method for operating a vehicle includes monitoring a state of the vehicle, determining a type of an emergency stop from a plurality of types of emergency stops based on the state of the vehicle, and executing the determined type of the emergency stop. An embodiment vehicle includes sensors, a processor configured to control automated driving of the vehicle based on state information of components of the vehicle and surrounding environment information of the vehicle detected by the sensors, and a controller configured to control an operation of the vehicle based on a control of the processor, wherein the processor is further configured to monitor a state of the vehicle, determine a type of an emergency stop from a plurality of types of emergency stops based on the state of the vehicle, and execute the determined type of the emergency stop by controlling the controller.
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公开(公告)号:US20230400698A1
公开(公告)日:2023-12-14
申请号:US18209627
申请日:2023-06-14
Applicant: SAMSUNG ELECTRONICS CO., LTD. , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Jangwoo YOU , Yongmin PARK , Jesung KOH , Changkun LEE , Sunpil JEONG , Kyujin CHO
CPC classification number: G02B27/0179 , G02B27/0149 , G02B27/0093 , G02B2027/0187 , G02B30/33
Abstract: A multi-degree of freedom (DOF) moving stage includes a plurality of joint portions. At least one of the plurality of joint portions has a joint structure including a first flexible member and first and second rigid members, the first and second rigid members being arranged apart from each other with a first gap therebetween such that the first gap exposes a first surface of the first flexible member. Castellated patterns having shapes complementary to each other are respectively provided at a first end portion of the first rigid member adjacent to the first gap and a second end portion of the second rigid member adjacent to the first gap.
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28.
公开(公告)号:US20230395742A1
公开(公告)日:2023-12-07
申请号:US18032720
申请日:2021-02-02
Inventor: Junseok HEO , Aujin HWANG , Youngseo PARK
IPC: H01L31/109 , H01L31/18
CPC classification number: H01L31/109 , H01L31/18
Abstract: Disclosed is an optical sensor including a three-dimensional (3D) material layer doped with first conductivity type impurities at a first doping concentration, and a two-dimensional material layer doped with second conductivity type impurities at a second doping concentration and arranged in contact with the three-dimensional material layer to form a type II band alignment with the three-dimensional material layer.
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公开(公告)号:US11826578B2
公开(公告)日:2023-11-28
申请号:US17559017
申请日:2021-12-22
Inventor: Chul Ho Kim , Sung Un Kang , Jae Won Choi
CPC classification number: A61N1/44 , A61K33/00 , C12N5/0658 , C12N2500/02
Abstract: The present invention relates to a method for producing a nitrogen-based non-thermal atmospheric pressure plasma for treating damaged muscles or promoting regeneration of damaged muscles, and to a method for treating damaged muscle or promoting regeneration of damaged muscles using the atmospheric pressure plasma. The nitrogen-based non-thermal atmospheric pressure plasma according to the present invention can effectively induce muscle cell activation, migration of muscle cells to damaged sites, muscle cell proliferation, and muscle cell differentiation, without surgical operation or during a treatment procedure after surgical operation, and thus can be advantageously used as a novel therapeutic agent and therapeutic method against muscle damage and muscle damage-associated diseases.
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公开(公告)号:US11824081B2
公开(公告)日:2023-11-21
申请号:US17209762
申请日:2021-03-23
Inventor: Changsoo Lee , Sangwoon Lee , Chan Kwak , Hyungjun Kim , Euncheol Do
IPC: H01L49/02 , H01L27/108 , C04B35/057 , C04B35/01 , C04B35/64 , C04B35/495 , H10B12/00
CPC classification number: H01L28/55 , C04B35/01 , C04B35/057 , C04B35/495 , C04B35/64 , H10B12/038 , H10B12/37
Abstract: Provided are a dielectric thin film, an integrated device including the same, and a method of manufacturing the dielectric thin film. The dielectric thin film includes an oxide having a perovskite-type crystal structure represented by Formula 1 below and wherein the dielectric thin film comprises 0.3 at % or less of halogen ions or sulfur ions.
A2-xB3-yO10-z
In Formula 1, A, B, x, y, and z are disclosed in the specification.
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