公开(公告)号：US20060124840A1

公开(公告)日：2006-06-15

申请号：US11297117

申请日：2005-12-08

Applicant: Katsumi Ida ,  Takeshi Ikeda

Inventor： Katsumi Ida ,  Takeshi Ikeda

IPC: G01J3/50

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0221 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/1804

Abstract: A spectroscope comprises an incident slit 12, a collimator lens type optical system 14 that makes the light rays having passed through the incident slit 12 parallel light rays, a reflection type diffraction grating 16 that receives the parallel light rays and, according to the wavelength, outputs these light rays at different angles, a condenser lens type optical system 14 that condenses the output light from the diffraction grating 16, and two-dimensional detector 16 having a two-dimensional light-receiving surface that detects the light rays that have been condensed by the condenser lens type optical system. The collimator lens type optical system and the condenser lens type optical system are disposed so that the angle 2γ defined between the optical axis of the collimator lens type optical system and the optical axis of the condenser lens type optical system may be acute. The condenser lens type optical system is disposed so that the distance between itself and the diffraction grating may be shorter than the distance between the collimator lens type optical system and the diffraction grating. A normal line vector at the central portion of the reflection surface of the diffraction grating may be directed, from a bisector of the angle defined between the optical axis of the collimator lens type optical system and the optical axis of the condenser lens type optical system, toward a side where the collimator lens type optical system is disposed.

Abstract translation: 分光器包括入射狭缝12，使穿过入射狭缝12的光线平行光的准直透镜型光学系统14，接收平行光线的反射型衍射光栅16，并且根据波长， 以不同的角度输出这些光线，会聚来自衍射光栅16的输出光的聚光透镜型光学系统14和具有二维光接收表面的二维检测器16，二维光接收表面检测已被冷凝的光线 由聚光镜型光学系统。 准直透镜型光学系统和聚光透镜型光学系统被设置为使得准直透镜型光学系统的光轴和聚光透镜型光学系统的光轴之间限定的角度2gam可能是尖锐的。 聚光透镜型光学系统被设置成使得其自身与衍射光栅之间的距离可以短于准直透镜型光学系统和衍射光栅之间的距离。 衍射光栅的反射面的中央部的法线矢量可以从准直透镜型光学系统的光轴与聚光透镜型光学系统的光轴之间的角度的二等分线指向， 朝向设置有准直透镜型光学系统的一侧。

公开(公告)号：US20060103841A1

公开(公告)日：2006-05-18

申请号：US11211619

申请日：2005-08-26

Applicant: Kazushi Ohishi ,  Hiroshi Ohta

Inventor： Kazushi Ohishi ,  Hiroshi Ohta

IPC: G01J3/28

CPC classification number: G01J3/1256 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0224 ,  G01J3/06 ,  G01J3/1804 ,  G01J2003/064

Abstract: An object of the invention is to realize an optical spectrum analyzer capable of performing high-speed waveform sweep. The invention is to make improvements to an optical spectrum analyzer for measuring a spectrum of light to be measured by collimating light to be measured by collimator means, spectroscopically separating the collimated light incident from the collimator means according to an incident angle by a diffraction grating, and detecting the light spectroscopically separated by the diffraction grating by a photodetector via a slit. The device is characterized by including an acoustooptic deflector provided between the collimator means and the diffraction grating for deflecting the collimated light to be measured and changing the incident angle on the diffraction grating.

Abstract translation: 本发明的目的是实现能够执行高速波形扫描的光谱分析仪。 本发明是为了对光谱分析仪进行改进，用于通过准直器准备待测光来测量待测光的光谱，通过衍射光栅根据入射角光谱分离入射到准直器装置的准直光， 并且通过光栅检测由光电检测器通过狭缝光谱地被衍射光栅分离的光。 该装置的特征在于包括设置在准直器装置和衍射光栅之间的声光偏转器，用于偏转待测量的准直光并改变衍射光栅上的入射角。

公开(公告)号：US06995844B2

公开(公告)日：2006-02-07

申请号：US10316707

申请日：2002-12-10

Applicant: Dean G. Hafeman ,  Calvin Y. Chow

Inventor： Dean G. Hafeman ,  Calvin Y. Chow

IPC: G01N21/59

CPC classification number: G01J3/08 ,  G01J3/1804 ,  G01N21/253 ,  G01N21/31 ,  G01N21/314 ,  G01N21/6452

Abstract: Disclosed are photometric methods and devices for determining optical pathlength of liquid samples containing analytes dissolved or suspended in a solvent. The methods and devices rely on determining a relationship between the light absorption properties of the solvent and the optical pathlength of liquid samples containing the solvent. This relationship is used to establish the optical pathlength for samples containing an unknown concentration of analyte but having similar solvent composition. Further disclosed are methods and devices for determining the concentration of analyte in such samples where both the optical pathlength and the concentration of analyte are unknown. The methods and devices rely on separately determining, at different wavelengths of light, light absorption by the solvent and light absorption by the analyte. Light absorption by the analyte, together with the optical pathlength so determined, is used to calculate the concentration of the analyte. Devices for carrying out the methods particularly advantageously include vertical-beam photometers containing samples disposed within the wells of multi-assay plates, wherein the photometer is able to monitor light absorption of each sample at multiple wavelengths, including in the visible or UV-visible region of the spectrum, as well as in the near-infrared region of the electromagnetic spectrum. Novel photometer devices are described which automatically determine the concentration of analytes in such multi-assay plates directly without employing a standard curve.

公开(公告)号：US06995840B2

公开(公告)日：2006-02-07

申请号：US10384374

申请日：2003-03-06

Applicant: Thomas W. Hagler

Inventor： Thomas W. Hagler

IPC: G01J3/06

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/06 ,  G01J3/1804 ,  G01J3/2846 ,  G01J3/42 ,  G01J2001/4242 ,  G01J2003/1217

Abstract: Method and apparatus for analyzing radiation using analyzers and encoders employing the spatial modulation of radiation dispersed by wavelength or imaged along a line.

Abstract translation: 使用分析器和编码器分析辐射的方法和装置，其采用通过波长分散的辐射的空间调制或沿着线成像。

公开(公告)号：US06783705B1

公开(公告)日：2004-08-31

申请号：US08834061

申请日：1997-04-11

Applicant: Michael J. Leveille

Inventor： Michael J. Leveille

IPC: F21V904

CPC classification number: G01J3/28 ,  G01J1/429 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0262 ,  G01J3/1804 ,  G01J2003/2866 ,  G01N21/276 ,  G01N21/278 ,  G01N21/31 ,  G01N21/33 ,  G01N2021/3155

Abstract: The invention features an optical medium for calibrating UV absorbance detectors, methods for making such an optical medium, and methods for calibrating UV absorbance detectors using such a medium. The optical calibration medium includes a gel-sol silica glass monolith with a rare-earth dopant therein. The rare-earth dopant exhibits at least one spectral feature in at least the far UV range. The constituents of the gel-sol silica glass monolith are selected so the rare-earth doped sol-gel glass monolith exhibits a transmittance in the far UV range so each distinct spectral feature of the rare-earth dopant in the far UV range is discernable. The transmittance in a particular embodiment is at least about 50% at about 250 nm. The rare earth materials selected for use as dopants are those exhibiting a wide range of spectral features, preferably over a range from about 190 nm to about 700 nm and more particularly exhibit at least one distinct spectral feature in the range from about 190 nm to about 300 nm. In a specific embodiment, the rare-earth dopant includes atoms of erbium, having spectral features in a range from about 190 nm to about 650 nm and a distinguishable far UV spectral feature at about 257 nm.

Abstract translation: 本发明的特征在于用于校准UV吸光度检测器的光学介质，用于制造这种光学介质的方法，以及使用这种介质校准UV吸光度检测器的方法。 光学校准介质包括其中具有稀土掺杂剂的凝胶 - 硅石玻璃整料。 至少在远紫外范围内，稀土掺杂剂表现出至少一个光谱特征。 选择凝胶溶胶石英玻璃整体的成分，使得稀土掺杂的溶胶 - 凝胶玻璃整体在远紫外范围内呈现透射率，因此在远紫外范围内的稀土掺杂剂的每个不同光谱特征是可辨别的。 在特定实施例中的透射率在约250nm处为至少约50％。 选择用作掺杂剂的稀土材料是表现出宽范围光谱特征的稀土材料，优选在约190nm至约700nm的范围内，更特别地，在约190nm至约700nm的范围内显示出至少一个不同的光谱特征 300 nm。 在具体实施方案中，稀土掺杂剂包括铒的原子，其具有在约190nm至约650nm范围内的光谱特征，以及在约257nm处的可区分的远紫外光谱特征。

公开(公告)号：US20040033072A1

公开(公告)日：2004-02-19

申请号：US10641387

申请日：2003-08-13

Inventor： Yasuhisa Kaneko

IPC: H04J014/02

CPC classification number: H04J14/02 ,  G01J3/1804 ,  G01J2003/1866

Abstract: A method and apparatus for measuring characteristics of a single-wavelength optical signal constituting part of a wavelength division multiplexed (WDM) optical signal is provided. The WDM optical signal is adjustably diffracted to select the single-wavelength optical signal. An optical-to-electrical conversion is performed. An electrical sampling signal representing the selected single-wavelength optical signal is generated by one of (a) optically sampling the selected single-wavelength optical signal to generate an optical sampling signal on which the optical-to-electrical conversion is performed, and (b) electrically sampling an electrical signal generated by performing the optical-to-electrical conversion on the selected single-wavelength optical signal.

Abstract translation: 提供了一种用于测量构成波分复用（WDM）光信号的一部分的单波长光信号的特性的方法和装置。 WDM光信号被可调谐地衍射以选择单波长光信号。 进行光电转换。 代表选择的单波长光信号的电采样信号由以下之一产生：（a）对所选择的单波长光信号进行光学采样以产生执行光电转换的光采样信号，（b ）对所选择的单波长光信号执行光电转换而产生的电信号进行电采样。

公开(公告)号：US06573990B1

公开(公告)日：2003-06-03

申请号：US09564298

申请日：2000-05-03

Applicant: Duwayne R. Anderson

Inventor： Duwayne R. Anderson

IPC: G01J328

CPC classification number: G01J3/1804 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0243 ,  G01J3/0294 ,  G01J2003/1828 ,  G01J2003/2866 ,  G02B6/3534 ,  G02B6/3568 ,  G02B6/3586

Abstract: An optical system having a first order spectral range that is usable in an optical spectrum analyzer receives an broadband optical test signal and a optical calibration signal and couples the optical signals via two optically isolated paths to separate optical detectors. First and second pairs of optical fibers, with each pair having an input fiber and an output fiber, are positioned in a focal plane of a collimating optic that has an optical axis. The fiber pairs are symmetrically positioned on either side of the optical axis with the input fibers positioned on one side of the optical axis and the output fibers positioned on the opposite side of the optical axis. The input fibers receive the optical test signal and the optical calibration signal. The output optical fibers are coupled to first and second optical detectors. An optical calibration source generates second order or greater spectral lines that fall within the first order spectral range of the optical system. A diffraction grating receives the optical test signal and the optical calibration signal from the collimating optic and separates the first order spectral components of the broadband optical test signal and passes the second order or greater spectral lines of the optical calibration signal. The first optical detector that is responsive to the first order spectral components of the optical test signal receives the optical test signal from the collimating optic and converts the optical test signal to an electrical signal. A second optical detector that is responsive to the second order or greater spectral lines of the optical calibration signal concurrently receives the optical calibration signal from the collimating optic and converts the calibrations signal to an electrical signal.

Abstract translation: 具有可用于光谱分析仪中的一阶光谱范围的光学系统接收宽带光学测试信号和光学校准信号，并且经由两个光学隔离路径将光信号耦合到分离的光学检测器。 每对具有输入光纤和输出光纤的第一和第二对光纤被定位在具有光轴的准直光学器件的焦平面中。 光纤对对称地位于光轴的任一侧，其中输入光纤位于光轴的一侧，并且输出光纤位于光轴的相反侧。 输入光纤接收光学测试信号和光学校准信号。 输出光纤耦合到第一和第二光学检测器。 光学校准源产生落在光学系统的一阶光谱范围内的第二级或更多光谱线。 衍射光栅接收来自准直光学器件的光学测试信号和光学校准信号，并分离宽带光学测试信号的一阶光谱分量，并通过光学校准信号的第二级或更多谱线。 响应于光学测试信号的一阶光谱分量的第一光学检测器从准直光学器件接收光学测试信号，并将光学测试信号转换为电信号。 响应于光学校准信号的二阶或更高谱线的第二光学检测器同时从准直光学器件接收光学校准信号，并将校准信号转换为电信号。

公开(公告)号：US20030077660A1

公开(公告)日：2003-04-24

申请号：US10253846

申请日：2002-09-25

Applicant: SRU BIOSYSTEMS, LLC

Inventor： Homer Pien ,  William C. Karl ,  Derek Puff ,  Peter Li ,  Brian Cunningham

IPC: G01N033/53 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50

CPC classification number: G01N21/7743 ,  B01L3/5085 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/1804 ,  G01J3/42 ,  G01N21/253 ,  G01N21/31 ,  G01N33/54373 ,  G01N2021/3196 ,  G01N2021/7773 ,  G02B5/1809 ,  Y10S436/805

Abstract: Performing high-resolution determination of the relative shift of the spectral properties of a biosensor. The shift in the resonance peak of the biosensor is indicative of the amount of material bound to the surface of the biosensor. A preferred biosensor is a Guided Mode Resonant Filter Biosensor (GMRFB). In one aspect of the invention, curve fitting is used to determine the relative location of the spectrum of the unexposed biosensor with respect to those spectra that are altered (e.g., shifted) by the presence of materials bound to the surface of the biosensor. In an alternative embodiment, the cross correlation function is used to detect spectral peak offsets between a reference spectrum and a spectrum measured from an exposed biosensor. In yet another alternative, maximal likelihood estimation techniques are used to determine the spectral shift or offs.

Abstract translation: 对生物传感器的光谱特性进行相对偏移的高分辨率测定。 生物传感器的共振峰的偏移指示与生物传感器的表面结合的材料的量。 优选的生物传感器是引导模式谐振滤波器生物传感器（GMRFB）。 在本发明的一个方面，使用曲线拟合来确定未暴露的生物传感器的光谱相对于通过存在与生物传感器的表面结合的材料而被改变（例如，偏移）的那些光谱的相对位置。 在替代实施例中，互相关函数用于检测参考光谱和从暴露的生物传感器测量的光谱之间的光谱峰值偏移。 在另一替代方案中，使用最大似然估计技术来确定频谱偏移或偏移。

公开(公告)号：US06496260B1

公开(公告)日：2002-12-17

申请号：US09220177

申请日：1998-12-23

Applicant: Dean G. Hafeman ,  Calvin Y. Chow

Inventor： Dean G. Hafeman ,  Calvin Y. Chow

IPC: G01N2159

CPC classification number: G01J3/08 ,  G01J3/1804 ,  G01N21/253 ,  G01N21/31 ,  G01N21/314 ,  G01N21/6452

Abstract: Disclosed are photometric methods and devices for determining optical pathlength of liquid samples containing analytes dissolved or suspended in a solvent. The methods and devices rely on determining a relationship between the light absorption properties of the solvent and the optical pathlength of liquid samples containing the solvent. This relationship is used to establish the optical pathlength for samples containing an unknown concentration of analyte but having similar solvent composition. Further disclosed are methods and devices for determining the concentration of analyte in such samples where both the optical pathlength and the concentration of analyte are unknown. The methods and devices rely on separately determining, at different wavelengths of light, light absorption by the solvent and light absorption by the analyte. Light absorption by the analyte, together with the optical pathlength so determined, is used to calculate the concentration of the analyte. Devices for carrying out the methods particularly advantageously include vertical-beam photometers containing samples disposed within the wells of multi-assay plates, wherein the photometer is able to monitor light absorption of each sample at multiple wavelengths, including in the visible or UV-visible region of the spectrum, as well as in the near-infrared region of the electromagnetic spectrum. Novel photometer devices are described which automatically determine the concentration of analytes in such multi-assay plates directly without employing a standard curve.

Abstract translation: 公开了用于确定含有溶解或悬浮在溶剂中的分析物的液体样品的光程长度的光度测定方法和装置。 所述方法和装置依赖于确定溶剂的光吸收性质和含有溶剂的液体样品的光程长度之间的关系。 该关系用于建立含有未知浓度的分析物但具有相似溶剂组成的样品的光程。 进一步公开了用于确定样品中分析物浓度的方法和装置，其中光程长和分析物浓度都是未知的。 方法和装置依赖于在不同波长的光下分别确定溶剂的光吸收和被分析物的光吸收。 被分析物的光吸收以及如此确定的光程长度被用于计算分析物的浓度。 用于实施方法的装置特别有利地包括垂直光束光度计，其包含设置在多测定板的孔内的样品，其中光度计能够监测包括在可见光或可见光区域中的多个波长的每个样品的光吸收 的光谱，以及在电磁光谱的近红外区域。 描述了新的光度计装置，其直接在不使用标准曲线的情况下自动确定这种多测定板中的分析物的浓度。

公开(公告)号：US06373606B1

公开(公告)日：2002-04-16

申请号：US09437953

申请日：1999-11-10

Applicant: Kenichi Nakama

Inventor： Kenichi Nakama

IPC: H04J1402

CPC classification number: H01L27/1446 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/1804 ,  G01J3/2803 ,  G02B6/2931 ,  G02B6/2938

Abstract: An optical demultiplexer has an optical fiber, a single collimator lens, a diffraction grating, and an array of photodetectors. A light beam emitted from the optical fiber is demultiplexed by the collimator lens and the diffraction grating into light beams, and the light beams are focused by the collimator lens as beam spots deformed due to an aberration of an optical system of the optical demultiplexer onto the photodetectors. The photodetectors are arranged to accommodate and detect all the deformed focused beam spots. The array of photodetectors comprises a linear array of photodetectors or a matrix of photodetectors.

Abstract translation: 光解复用器具有光纤，单个准直透镜，衍射光栅和光电检测器阵列。 从光纤发射的光束被准直透镜和衍射光栅解复用为光束，并且由于光解复用器的光学系统的像差而导致的光斑变形的光束被准直透镜聚焦 光电探测器 光电检测器布置成适应和检测所有变形的聚焦光束斑点。 光电检测器阵列包括光电检测器的线性阵列或光电检测器的矩阵。