公开(公告)号：US20190062689A1

公开(公告)日：2019-02-28

申请号：US16100175

申请日：2018-08-09

Applicant: OLYMPUS CORPORATION

Inventor： Naohiro ARIGA ,  Toshiyuki HATTORI ,  Mina KOBAYASHI ,  Ayumu SAKURAI

IPC: C12M1/00 ,  C12M1/36 ,  C12M1/34 ,  G06T7/11 ,  H04N5/30

Abstract: A culture monitoring system includes: an image acquisition device that is arranged in an incubator and acquires an image of a biological sample cultured in the incubator; and a controller that controls the image acquisition device. The controller includes an estimator that estimates a state of a temperature of the biological sample with respect to a set temperature of the incubator, and a device controller that restricts an operation of the image acquisition device at least according to the state.

公开(公告)号：US20180346869A1

公开(公告)日：2018-12-06

申请号：US15987513

申请日：2018-05-23

Applicant: OLYMPUS CORPORATION

Inventor： Naohiro ARIGA ,  Toshiyuki HATTORI ,  Mina KOBAYASHI ,  Ayumu SAKURAI

IPC: C12M1/34 ,  C12M1/00

CPC classification number: C12M41/36 ,  C12M41/14 ,  C12M41/48

Abstract: A cell culture monitoring system includes measuring units housed in an incubator and each equipped with an indicator, the measuring units each measuring a state of cells in a culture container mounted therein; and an administration unit. The administration unit includes a receiver that receives, from each of the measuring units, a state of the cells measured, the state being associated with identification information of the measuring unit; an analyzer that analyzes the state of the cells and computes information indicating a culture state; a storage that stores, in association with each other, the information indicating the culture state and the identification information; a display that displays, in association with each other, the information indicating the culture state and an identification based on the identification information; and a controller that controls the indicators so that each of the indicators displays the identification corresponding to the identification displayed on the display.

公开(公告)号：US20180314046A1

公开(公告)日：2018-11-01

申请号：US15959610

申请日：2018-04-23

Applicant: OLYMPUS CORPORATION

Inventor： Ayumu SAKURAI ,  Mina KOBAYASHI ,  Toshiyuki HATTORI ,  Naohiro ARIGA ,  Takashi MIYOSHI

IPC: G02B21/08 ,  C12M1/34 ,  G02B21/14 ,  G02B21/26 ,  G02B21/36

CPC classification number: G02B21/06 ,  G02B21/365 ,  G06K2009/3225 ,  G06T5/008

Abstract: An observation device including: an imaging element that captures images of cells contained in a culture vessel; an oblique illumination device that performs oblique illumination to the cells from a plurality of illumination directions, out of the optical axis of the imaging element; a controller that detects the relationship between the position of the culture vessel and the position of the imaging element and that selects the illumination directions of the oblique illumination device on the basis of the detected relationship between the position of the culture vessel and the position of the imaging element; and an image processor that applies, on the basis of the illumination direction of the oblique illumination device, processing for reducing shadows on the cells caused by the oblique illumination, to an image of the cells acquired by the imaging element.