公开(公告)号：US20030207392A1

公开(公告)日：2003-11-06

申请号：US10179509

申请日：2002-06-24

Applicant: Genentech, Inc.

Inventor： Kevin P. Baker ,  Jian Chen ,  Luc Desnoyers ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  James Pan ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood ,  Zemin Zhang

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030206915A1

公开(公告)日：2003-11-06

申请号：US10013916

申请日：2001-10-25

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/47 ,  C07H021/04 ,  C12N009/00 ,  A61K039/00

CPC classification number: C07K14/4703 ,  A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026 ,  C12N2799/027

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030204054A1

公开(公告)日：2003-10-30

申请号：US10015394

申请日：2001-12-11

Applicant: Genentech, Inc.

Inventor： Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Wei-Qiang Gao ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  Victoria Smith ,  Timothy A. Stewart ,  Daniel Tumas ,  Colin K. Watanabe ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/47 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/47 ,  C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030203436A1

公开(公告)日：2003-10-30

申请号：US10145129

申请日：2001-10-18

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/705 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K16/18 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/02

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030203433A1

公开(公告)日：2003-10-30

申请号：US10145016

申请日：2001-10-18

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K16/18 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/02

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030203402A1

公开(公告)日：2003-10-30

申请号：US10017084

申请日：2001-10-24

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: G01N033/53 ,  C07H021/04 ,  C12N009/00 ,  C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07K016/40 ,  A61K038/17

CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  C07K14/4702 ,  C07K14/4703 ,  C07K14/475 ,  C07K14/52 ,  C07K14/521 ,  C07K14/54 ,  C07K14/705 ,  C07K14/70503 ,  C07K14/70578 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N9/00 ,  C12N2799/026 ,  C12N2799/027 ,  G01N33/573 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/99 ,  G01N2800/042

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030199437A1

公开(公告)日：2003-10-23

申请号：US09978665

申请日：2001-10-16

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  Williams I. Wood

IPC: G01N033/53 ,  A61K038/17 ,  C07K014/435 ,  C12P021/02 ,  C12N005/06 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  C07K14/4702 ,  C07K14/4703 ,  C07K14/475 ,  C07K14/52 ,  C07K14/521 ,  C07K14/54 ,  C07K14/705 ,  C07K14/70503 ,  C07K14/70578 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N9/00 ,  C12N2799/026 ,  C12N2799/027 ,  G01N33/573 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/99 ,  G01N2800/042

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030199021A1

公开(公告)日：2003-10-23

申请号：US10013924

申请日：2001-10-25

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey Williams ,  William I. Wood

IPC: C12P021/02 ,  C12N005/06 ,  C07K014/47 ,  C07H021/04 ,  C12N009/00

CPC classification number: C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030198993A1

公开(公告)日：2003-10-23

申请号：US10007236

申请日：2001-12-06

Applicant: Genentech, Inc.

Inventor： Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Wei-Qiang Gao ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  Victoria Smith ,  Timothy A. Stewart ,  Daniel Tumas ,  Colin K. Watanabe ,  P. Mickey Williams ,  William I. Wood

IPC: G01N033/53 ,  C07H021/04 ,  C12N009/00 ,  C12P021/02 ,  C12N005/06 ,  C07K014/435 ,  C07K016/40

CPC classification number: C07K14/47 ,  C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20030195148A1

公开(公告)日：2003-10-16

申请号：US09978681

申请日：2001-10-16

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi ,  Kevin P. Baker ,  David Botstein ,  Luc Desnoyers ,  Dan L. Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Ivar J. Kljavin ,  Sophia S. Kuo ,  Mary A. Napier ,  James Pan ,  Nicholas F. Paoni ,  Margaret Ann Roy ,  David L. Shelton ,  Timothy A. Stewart ,  Daniel Tumas ,  P. Mickey William ,  William I. Wood

IPC: A61K038/17 ,  G01N033/53 ,  C12P021/02 ,  C12N005/06 ,  C07K014/435

CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  C07K14/4702 ,  C07K14/4703 ,  C07K14/475 ,  C07K14/52 ,  C07K14/521 ,  C07K14/54 ,  C07K14/705 ,  C07K14/70503 ,  C07K14/70578 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N9/00 ,  C12N2799/026 ,  C12N2799/027 ,  G01N33/573 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/99 ,  G01N2800/042

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.