公开(公告)号：US20160174919A1

公开(公告)日：2016-06-23

申请号：US14579039

申请日：2014-12-22

Applicant: General Electric Company

Inventor： Sangtae Ahn ,  Ravindra Mohan Manjeshwar ,  Florian Wiesinger ,  Dattesh Dayanand Shanbhag ,  Sandeep Suryanarayana Kaushik ,  Hua Qian ,  Anne Menini

IPC: A61B6/00 ,  G01T1/24 ,  G06T7/00 ,  A61B8/00 ,  A61B6/03 ,  A61B5/055 ,  A61B5/00 ,  A61B5/053 ,  G01R33/56 ,  G06T11/00

CPC classification number: A61B6/4417 ,  A61B5/0059 ,  A61B5/0536 ,  A61B5/055 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5205 ,  A61B6/5258 ,  A61B8/4416 ,  G01R33/481 ,  G01R33/56 ,  G01T1/1603 ,  G01T1/1647 ,  G01T1/249 ,  G06T7/0012 ,  G06T11/003 ,  G06T11/006 ,  G06T2200/04 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/30024 ,  G06T2207/30061 ,  G06T2211/40 ,  G06T2211/424

Abstract: Imaging system and method are presented. Emission scan (ES) and anatomical scan (AS) data corresponding to a target volume in a subject are received. One or more at least partial AS images are reconstructed using AS data. An image-space certainty (IC) map representing a confidence level (CL) for attenuation coefficients of selected voxels in AS images and a preliminary attenuation (PA) map based on AS images are generated. One or more of selected attenuation factors (AF) in projection-space are initialized based on PA map. A projection-space certainty (PC) map representing CL for the selected AF is generated based on IC map. An emission image of the target volume is initialized. The selected AF and emission image are iteratively updated based on the ES data, PC map, initial AF, and/or initial emission image. A desired emission image and/or AF values are determined based on the iteratively updated AF and/or emission image.

Abstract translation: 介绍了成像系统和方法。 接收与对象中的目标体积对应的发射扫描（ES）和解剖扫描（AS）数据。 使用AS数据重构一个或多个至少部分AS图像。 生成表示AS图像中的选定体素的衰减系数的置信水平（CL）和基于AS图像的初步衰减（PA）图的图像空间确定性（IC）图。 基于PA映射初始化投影空间中的一个或多个选择的衰减因子（AF）。 基于IC映射生成表示所选AF的CL的投影空间确定性（PC）映射。 初始化目标体积的发射图像。 基于ES数据，PC映射，初始AF和/或初始发射图像迭代地更新所选择的AF和发​​射图像。 基于迭代更新的AF和/或发射图像来确定期望的发射图像和/或AF值。

公开(公告)号：US10076249B2

公开(公告)日：2018-09-18

申请号：US14817450

申请日：2015-08-04

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Silke Maria Lechner-Greite ,  Florian Wiesinger ,  Desmond Teck Beng Yeo ,  Matthew Richard Tarasek

IPC: A61B5/00 ,  A61B5/01 ,  G01R33/48 ,  G01R33/56 ,  A61B18/18 ,  A61B18/00 ,  A61B18/02 ,  A61B18/04

CPC classification number: A61B5/015 ,  A61B5/055 ,  A61B5/4836 ,  A61B5/7214 ,  A61B5/7285 ,  A61B18/02 ,  A61B18/04 ,  A61B18/1815 ,  A61B2018/00577 ,  A61B2018/00791 ,  G01R33/4804 ,  G01R33/4814 ,  G01R33/4816 ,  G01R33/5602

Abstract: A system and method for tracking temperature changes in tissue and bone is disclosed. In one aspect, the temperature changes are tracked simultaneously with high spatial encoding and temporal efficiency. The method is robust in terms of B0 and chemical shift off-resonance, as well as insensitive to eddy currents for accurate temperature mapping. Zero TE (ZTE) based MR thermometry is utilized herein to extract temperature changes from proton density and T1 weighted images. Additionally, T1 signal contamination is corrected for by calibrating T1 and B0 by using a variable flip angle method to achieve temperature mapping in bone, aqueous and adipose tissue simultaneously.

公开(公告)号：US09645214B2

公开(公告)日：2017-05-09

申请号：US14095707

申请日：2013-12-03

Applicant: General Electric Company

Inventor： Ileana Hancu ,  Selaka Bandara Bulumulla ,  Florian Wiesinger ,  Laura Irene Sacolick ,  Seung Kyun Lee

IPC: G01V3/00 ,  G01R33/48 ,  G01R33/24

CPC classification number: G01R33/4816 ,  G01R33/246

Abstract: Systems and methods for determining electrical properties using Magnetic Resonance Imaging (MRI) are provided. One method includes applying an ultra-short echo time (TE) pulse sequence in a Magnetic Resonance Imaging (MRI) system and acquiring a complex B1+B1− quantity from an object following the application of the ultra-short TE pulse sequence, where B1+ is a complex amplitude of a transmit radio-frequency (RF) magnetic field and B1− is a complex amplitude of a receive RF magnetic field. The method also includes estimating, with a processor, one or more electrical properties of the object using the complex amplitudes of the transmit RF magnetic field and the receive RF magnetic field.

公开(公告)号：US09474495B2

公开(公告)日：2016-10-25

申请号：US14579039

申请日：2014-12-22

Applicant: General Electric Company

Inventor： Sangtae Ahn ,  Ravindra Mohan Manjeshwar ,  Florian Wiesinger ,  Dattesh Dayanand Shanbhag ,  Sandeep Suryanarayana Kaushik ,  Hua Qian ,  Anne Menini

IPC: A61B6/00 ,  G06T7/00 ,  G01R33/56 ,  G01T1/24 ,  G06T11/00 ,  A61B6/03 ,  A61B5/055 ,  A61B5/00 ,  A61B5/053 ,  A61B8/00

CPC classification number: A61B6/4417 ,  A61B5/0059 ,  A61B5/0536 ,  A61B5/055 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5205 ,  A61B6/5258 ,  A61B8/4416 ,  G01R33/481 ,  G01R33/56 ,  G01T1/1603 ,  G01T1/1647 ,  G01T1/249 ,  G06T7/0012 ,  G06T11/003 ,  G06T11/006 ,  G06T2200/04 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/30024 ,  G06T2207/30061 ,  G06T2211/40 ,  G06T2211/424

Abstract: Imaging system and method are presented. Emission scan (ES) and anatomical scan (AS) data corresponding to a target volume in a subject are received. One or more at least partial AS images are reconstructed using AS data. An image-space certainty (IC) map representing a confidence level (CL) for attenuation coefficients of selected voxels in AS images and a preliminary attenuation (PA) map based on AS images are generated. One or more of selected attenuation factors (AF) in projection-space are initialized based on PA map. A projection-space certainty (PC) map representing CL for the selected AF is generated based on IC map. An emission image of the target volume is initialized. The selected AF and emission image are iteratively updated based on the ES data, PC map, initial AF, and/or initial emission image. A desired emission image and/or AF values are determined based on the iteratively updated AF and/or emission image.

Abstract translation: 介绍了成像系统和方法。 接收与对象中的目标体积对应的发射扫描（ES）和解剖扫描（AS）数据。 使用AS数据重构一个或多个至少部分AS图像。 生成表示AS图像中的选定体素的衰减系数的置信水平（CL）和基于AS图像的初步衰减（PA）图的图像空间确定性（IC）图。 基于PA映射初始化投影空间中的一个或多个选择的衰减因子（AF）。 基于IC映射生成表示所选AF的CL的投影空间确定性（PC）映射。 初始化目标体积的发射图像。 基于ES数据，PC映射，初始AF和/或初始发射图像迭代地更新所选择的AF和发​​射图像。 基于迭代更新的AF和/或发射图像来确定期望的发射图像和/或AF值。

公开(公告)号：US10088539B2

公开(公告)日：2018-10-02

申请号：US15142957

申请日：2016-04-29

Applicant: General Electric Company

Inventor： Florian Wiesinger ,  Anne Menini ,  Ana Beatriz Solana Sanchez

IPC: G01R33/385 ,  G01R33/48 ,  G01R33/561

Abstract: Methods and systems for production of silent, multi-gradient-echo, magnetic resonance images are provided. The methods employ iterative application of small updates to the magnetic field gradient followed by a short, non-selective radiofrequency pulse excitation and for free induction decay data acquisition. The magnetic field gradient updates allow for silent, self-refocusing pulse sequence. Subsequent applications of the magnetic field gradients allow for multiple echo data acquisitions, which may allow fast, silent production of T2*-weighted images.

公开(公告)号：US20180038928A1

公开(公告)日：2018-02-08

申请号：US15228881

申请日：2016-08-04

Applicant: General Electric Company

Inventor： Florian Wiesinger ,  Martin Andreas Janich ,  Ana Beatriz Solana Sanchez ,  Nicolas Hehn

IPC: G01R33/50 ,  G01R33/565 ,  G01R33/561

CPC classification number: G01R33/50 ,  G01R33/5602 ,  G01R33/5618 ,  G01R33/56563 ,  G01R33/5659

Abstract: Methods and systems to obtain and apply T2 preparatory radiofrequency (RF) pulse sequences for magnetic resonance imaging (MRI) are provided. The iterative methods may employ propagation of the magnetization state of the object being imaged and a comparison with a target magnetization state. The methods disclosed may be used to obtain MRI pulse sequences that may optimize T2 relaxation contrast. The produced RF pulse sequences may be robust to effects from inhomogeneity of the magnetic fields or other environmental or physiological perturbations.

公开(公告)号：US09760991B2

公开(公告)日：2017-09-12

申请号：US14786508

申请日：2014-04-21

Applicant: General Electric Company

Inventor： Sheshadri Thiruvenkadam ,  Rakesh Mullick ,  Sandeep Kaushik ,  Hua Qian ,  Dattesh Shanbhag ,  Florian Wiesinger

IPC: G06K9/00 ,  G06T7/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  G06T5/20 ,  G06T7/11 ,  G06T7/12 ,  G06T7/149 ,  G06T7/174 ,  G06T7/136

CPC classification number: G06T7/0012 ,  A61B5/055 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  G06T5/20 ,  G06T7/11 ,  G06T7/12 ,  G06T7/136 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/20116 ,  G06T2207/30004 ,  G06T2207/30024 ,  G06T2210/41

Abstract: A system and method for estimating image intensity bias and segmentation tissues is presented. The system and method includes obtaining a first image data set and at least a second image data set, wherein the first and second image data sets are representative of an anatomical region in a subject of interest. Furthermore, the system and method includes generating a baseline bias map by processing the first image data set. The system and method also includes determining a baseline body mask by processing the second image data set. In addition, the system and method includes estimating a bias map corresponding to a sub-region in the anatomical region based on the baseline body mask. Moreover, the system and method includes segmenting one or more tissues in the anatomical region based on the bias map.

公开(公告)号：US09706972B1

公开(公告)日：2017-07-18

申请号：US15278652

申请日：2016-09-28

Applicant: General Electric Company

Inventor： Sangtae Ahn ,  Lishui Cheng ,  Florian Wiesinger ,  Dirk Bequé ,  Sandeep Suryanarayana Kaushik ,  Dattesh Dayanand Shanbhag

IPC: G01T1/164 ,  A61B6/00 ,  G01T1/29 ,  G01T1/17 ,  A61B6/03 ,  A61B6/02 ,  G06T7/00 ,  G06T3/40 ,  G06T11/00

CPC classification number: A61B6/5235 ,  A61B6/025 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4085 ,  A61B6/461 ,  A61B6/502 ,  A61B6/5205 ,  G01T1/1647 ,  G01T1/17 ,  G06T11/006 ,  G06T2211/424 ,  G06T2211/432

Abstract: Aspects of the invention relate to generating an emission activity image as well as an emission attenuation map using an iterative updation based on both the raw emission projection data and the raw radiography projection data, and an optimization function. The outputs include an optimized emission activity image, and at least one of an optimized emission attenuation map or an optimized radiography image. In some aspects an attenuated corrected emission activity image is obtained using the optimized emission activity image, and the optimized emission attenuation map.

公开(公告)号：US20160071263A1

公开(公告)日：2016-03-10

申请号：US14786508

申请日：2014-04-21

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Sheshadri Thiruvenkadam ,  Rakesh Mullick ,  Sandeep Kaushik ,  Hua Qian ,  Dattesh Shanbhag ,  Florian Wiesinger

IPC: G06T7/00 ,  A61B8/13 ,  A61B6/03 ,  G06T5/20 ,  A61B5/055

CPC classification number: G06T7/0012 ,  A61B5/055 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  G06T5/20 ,  G06T7/11 ,  G06T7/12 ,  G06T7/136 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/20116 ,  G06T2207/30004 ,  G06T2207/30024 ,  G06T2210/41

Abstract: A system and method for estimating image intensity bias and segmentation tissues is presented. The system and method includes obtaining a first image data set and at least a second image data set, wherein the first and second image data sets are representative of an anatomical region in a subject of interest. Furthermore, the system and method includes generating a baseline bias map by processing the first image data set. The system and method also includes determining a baseline body mask by processing the second image data set. In addition, the system and method includes estimating a bias map corresponding to a sub-region in the anatomical region based on the baseline body mask. Moreover, the system and method includes segmenting one or more tissues in the anatomical region based on the bias map.

Abstract translation: 提出了一种用于估计图像强度偏差和分割组织的系统和方法。 该系统和方法包括获得第一图像数据集和至少第二图像数据集，其中第一和第二图像数据集代表感兴趣对象中的解剖区域。 此外，该系统和方法包括通过处理第一图像数据集来生成基线偏置图。 该系统和方法还包括通过处理第二图像数据集来确定基线体掩模。 另外，该系统和方法包括基于基线体掩模估计对应于解剖区域中的子区域的偏置图。 此外，系统和方法包括基于偏置图分割解剖区域中的一个或多个组织。

公开(公告)号：US09254111B2

公开(公告)日：2016-02-09

申请号：US13686226

申请日：2012-11-27

Applicant: General Electric Company

Inventor： Thomas Kwok-Fah Foo ,  Christopher Judson Hardy ,  Charles William Stearns ,  Ravindra Mohan Manjeshwar ,  Florian Wiesinger ,  Dattesh Dayanand Shanbhag

IPC: A61B6/00 ,  A61B5/00 ,  A61B5/055 ,  A61B6/02 ,  A61B6/04 ,  A61B6/03

CPC classification number: A61B6/5247 ,  A61B5/0035 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/0555 ,  A61B5/7289 ,  A61B5/7292 ,  A61B6/02 ,  A61B6/037 ,  A61B6/04 ,  A61B6/0407 ,  A61B6/4417 ,  A61B6/461 ,  A61B6/469 ,  A61B6/488 ,  A61B6/541 ,  A61B6/542 ,  A61B6/545 ,  A61B6/548

Abstract: Exemplary embodiments of the present disclosure are directed to scheduling positron emission tomography (PET) scans for a combined PET-MRI scanner based on an acquisition of MR scout images of a subject. An anatomy and orientation of the subject can be determined based on the MR scout images and the schedule for acquiring PET scans of the subject can be determined from the anatomy of the subject. The schedule generated using exemplary embodiments of the present disclosure can specify a sequence of bed positions, scan durations at each bed position, and whether respiratory gating will be used at one or more of the bed positions.

Abstract translation: 本公开的示例性实施例涉及基于对受试者的MR侦察图像的获取来调度用于组合的PET-MRI扫描仪的正电子发射断层摄影（PET）扫描。 可以基于MR侦察图像来确定被摄体的解剖结构和取向，并且可以从对象的解剖结构确定用于获取对象的PET扫描的时间表。 使用本公开的示例性实施例产生的日程表可以指定床位置的顺序，每个床位置处的扫描持续时间，以及是否在一个或多个床位置使用呼吸门控。