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公开(公告)号：US10155077B2
公开(公告)日：2018-12-18
申请号：US14542947
申请日：2014-11-17
发明人： Andreas Maierhofer , Alfred Gagel , Malte Gross , Michael Koch
IPC分类号： A61M1/16
摘要： A dialysis machine has at least one filter for the filtration of dialysis liquid and a device for determining calcification of the dialysis machine. The device has one or more sensors configured and arranged to detect either downstream, or upstream and downstream, of the at least one filter an ion concentration or a parameter representative of the ion concentration or of its change of the dialysis liquid, of a solution serving the decalcification or of another measuring solution. The device for determining the calcification of the dialysis machine has an evaluation or calcification unit configured to determine the calcification of the dialysis machine based on the ion concentration or parameter value detected by the sensor or sensors.
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公开(公告)号：US10010289B2
公开(公告)日：2018-07-03
申请号：US13917944
申请日：2013-06-14
发明人： Alfred Gagel , Andreas Maierhofer
CPC分类号： A61B5/4848 , A61B5/0071 , A61B5/05 , A61B5/14546 , A61B5/1455 , A61B5/14558 , A61B5/4836 , A61B5/6866 , A61B5/7225 , A61M1/16 , A61M1/1609 , A61M1/1619 , A61M1/28 , A61M1/3406 , A61M2205/3306
摘要： The present invention pertains to Method for monitoring a dialysis treatment of a patient, preferably for monitoring a haemodialysis, haemodiafiltration and/or peritoneal dialysis treatment of a patient, the method including the steps of: irradiating a sample of a dialysis fluid used in the dialysis treatment with linearly polarized irradiation light; detecting the intensity of the fluorescence light emitted by the dialysis fluid in a first polarization plane; detecting the intensity of the fluorescence light emitted by the dialysis fluid in a second polarization plane which is different from the first polarization plane; determining the anisotropy of the fluorescence light emitted by the dialysis fluid; and determining the concentration of at least one fluorophore in the dialysis fluid on the basis of both, the determined anisotropy and the intensity of the fluorescence light emitted by the dialysis fluid.
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公开(公告)号：US20170224897A1
公开(公告)日：2017-08-10
申请号：US15501180
申请日：2015-07-20
CPC分类号： A61M1/1615 , A61M1/1617 , A61M1/341 , A61M1/3413 , A61M2205/3334 , A61M2205/70
摘要： The invention relates to a method and to a device for determining an optimum dialysate flow Qdopt for an extracorporeal blood treatment and to a blood treatment device comprising a device 18 for determining an optimum dialysate flow Qdopt. The optimum dialysate flow Qdopt is determined on the basis of a relationship describing the dependence of the clearance K on the dialysate flow Qd. The device according to the invention comprises a measurement device 18B for measuring at least one value which is characteristic of the clearance K, a calculation and/or evaluation unit 18A of the device according to the invention being configured in such a way that the clearance K is determined on the basis of the at least one value which is characteristic of the clearance. The calculation and/or evaluation unit 18A is configured in such a way that the optimum dialysate flow Qdopt is determined from the relationship describing the dependence of the clearance K on the dialysate rate Qd on the basis of the measured clearance K, or the optimum dialysate flow Qdopt is determined from the measured clearance K.
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公开(公告)号：US20170209634A1
公开(公告)日：2017-07-27
申请号：US15328691
申请日：2015-07-20
发明人： Andreas Maierhofer
IPC分类号： A61M1/16
摘要： The invention relates to a device and a method for detecting the direction of fluid flow through a dialyser 1 which comprises a blood chamber 4, through which blood flows, and a dialysate chamber 3, through which dialysate flows, which are separated from one another by a semi-permeable membrane 2. In addition, the invention relates to an extracorporeal blood treatment device comprising a device for detecting the flow direction. A first aspect of the invention is to measure the clearance in order to detect the flow direction and to compare the measured clearance with a specified limit value, a flow direction in countercurrent flow being concluded if the clearance is greater than the specified limit value. This aspect is based on the finding that in the case of blood treatment in practice with operation of the dialyser in co-current flow, clearance values above a certain limit value can no longer be achieved. A second aspect of the invention is to measure the clearance to detect the flow direction and to change the flow rate of the dialysate. Checking the flow direction according to the second aspect is based on the comparison of the measured change in clearance with a calculated expected value of the change in clearance for operation of the dialyser in both countercurrent flow and co-current flow. The invention according to the second aspect is based on the finding that the amount of the relative change in clearance in the event of a change in dialysate rate is always greater in the case of operation in co-current flow than in countercurrent flow.
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公开(公告)号：US09610395B2
公开(公告)日：2017-04-04
申请号：US14306570
申请日：2014-06-17
发明人： Andreas Maierhofer , Malte Gross
IPC分类号： A61M1/36 , F16K11/074 , A61M39/10 , A61M39/22
CPC分类号： A61M1/367 , A61M1/3656 , A61M1/3663 , A61M39/10 , A61M39/105 , A61M39/1055 , A61M39/22 , A61M39/223 , A61M2039/1044 , A61M2039/229 , A61M2205/3515 , A61M2205/3561 , A61M2205/3569 , A61M2205/6018 , A61M2205/6054 , F16K11/074
摘要： The invention relates to a device for reversing the blood flow for an extracorporeal blood treatment device, comprising an extracorporeal blood circuit (I), which includes an arterial blood line (108A) leading from a patient to a blood treatment unit (204) and a venous blood line (106A) leading from the blood treatment unit to the patient. Furthermore, the invention relates to an extracorporeal blood treatment device with a device for reversing the blood flow, and to a method for determining the reversal of the blood flow during an extracorporeal blood treatment. The device for reversing the blood flow for an extracorporeal blood treatment device according to the invention comprises two valve bodies (102, 104) which are rotated relative to one another for reversing the blood flow. The device for reversing the blood flow according to the invention is characterized by a communication device (210) for receiving an electromagnetic high-frequency field from a read unit (270) of the extracorporeal blood treatment device and for generating at least one identifier characterizing the position of the valve bodies which can be read by the read device.
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16.发明公开公开(公告)号：US20230414848A1
公开(公告)日：2023-12-28
申请号：US18462881
申请日：2023-09-07
发明人： Andreas Maierhofer
IPC分类号： A61M1/16 , A61M1/34 , G16H20/40 , G16H50/50 , G16H50/30 , G16H50/20 , G16H40/40 , G16H40/63 , G05B6/02
CPC分类号： A61M1/1611 , A61M1/1605 , A61M1/1613 , A61M1/341 , G16H20/40 , G16H50/50 , G16H50/30 , G16H50/20 , G16H40/40 , G16H40/63 , A61M1/1656 , G05B6/02
摘要： A method for determining a treatment regimen for altering the treatment parameters when dialyzing a patient over a plurality of treatment sessions taking place on future days includes determining a diffusive total target sodium balance; and determining a transitional treatment regimen by which the diffusive total target sodium balance is achieved over the plurality of future treatment sessions. A control device or closed-loop control device is configured to control a blood treatment apparatus using the method.
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公开(公告)号：US11529450B2
公开(公告)日：2022-12-20
申请号：US15998566
申请日：2017-02-15
发明人： Andreas Maierhofer , Wei Zhang
IPC分类号： A61M1/36
摘要： The invention relates to a blood treatment device having an extracorporeal blood circuit which comprises an arterial line, a blood pump, a blood treatment unit and a venous line, wherein the arterial and venous lines can be connected to a blood vessel of a patient, and wherein the blood treatment device has an evaluation and control unit, wherein the evaluation and control unit is configured to carry out the following steps: (a1) determining the blood recirculation in a blood vessel of the patient connected to the extracorporeal blood circuit; and (b) calculating the blood flow in the blood vessel using the blood recirculation determined in accordance with (a1) and using a provided value or a value likewise previously determined for the cardiac output of the patient.
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18.发明授权公开(公告)号：US10532140B2
公开(公告)日：2020-01-14
申请号：US15521571
申请日：2015-10-22
发明人： Andreas Maierhofer
摘要： The invention relates to a system comprising a plurality of medical devices, preferably dialysis devices, which are connected to a common supply system, wherein the system has an evaluation unit which is connected to all devices of the system and which is configured such that values set in the different devices and/or predefined values and/or measured values, which are determined by means of at least one sensor and which relate to corresponding parameters, are compared with at least one expected value for recognizing errors of the supply system and/or of an individual device.
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