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公开(公告)号:US20230055979A1
公开(公告)日:2023-02-23
申请号:US17820496
申请日:2022-08-17
Applicant: California Institute of Technology
Inventor: Lihong Wang , Rui Cao
IPC: G01N21/17 , H04N13/254 , H04N13/271 , H04N13/15 , G06V20/69
Abstract: Methods, devices, apparatus, and systems for three-dimensional (3D) contoured scanning photoacoustic imaging and/or deep learning virtual staining.
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公开(公告)号:US11471326B2
公开(公告)日:2022-10-18
申请号:US16178190
申请日:2018-11-01
Applicant: California Institute of Technology
Inventor: Lihong Wang , Frank L. Brodie , Yuecheng Shen , Yan Liu , Haowen Ruan
Abstract: A device for irradiating ocular tissue, including a source of electromagnetic radiation; a beacon scattering the electromagnetic radiation transmitted through an opacity in ocular tissue so as to form scattered electromagnetic radiation; a modulator transmitting output electromagnetic radiation having a field determined from a recording of the scattered electromagnetic radiation transmitted through the opacity, so that the output electromagnetic radiation is transmitted through the opacity to the beacon. The device can be used to treat amblyopia or correct optical aberrations in corneal or lens tissue.
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公开(公告)号:US20200275846A1
公开(公告)日:2020-09-03
申请号:US16806796
申请日:2020-03-02
Applicant: California Institute of Technology
Inventor: Lihong Wang , Xiaoming Wei
IPC: A61B5/0285 , A61B5/00
Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of velocity-matched ultrasonic tagging in photoacoustic flowgraphy.
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公开(公告)号:US20200056986A1
公开(公告)日:2020-02-20
申请号:US16540936
申请日:2019-08-14
Applicant: California Institute of Technology
Inventor: Lihong Wang , Yang Li , Tsz Wai Wong
IPC: G01N21/17
Abstract: Multifocal photoacoustic imaging systems and methods that implement an ergodic relay to encode photoacoustic signals detected from a plurality of illuminated optical foci regions.
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公开(公告)号:US12143557B2
公开(公告)日:2024-11-12
申请号:US18465325
申请日:2023-09-12
Applicant: California Institute of Technology
Inventor: Lihong Wang , Taewoo Kim , Jinyang Liang , Liren Zhu
IPC: H04N13/161 , G01J9/00 , G01J11/00 , G01S7/481 , G01S7/4865 , G01S17/894 , G02B5/04 , G02B21/10 , H04N13/25 , H04N13/254 , H04N13/282 , H04N23/72
Abstract: Compressed ultrafast photography (CUP) techniques that produce spatially encoded images from a first series of images where each spatially encoded image has first and second views of an image of the first series of images superimposed with a pseudo-random binary spatial pattern, that transform the first view and/or the second view such that the first view is rotated 180° relative to second view, that deflect each spatially encoded image by a temporal deflection distance that varies as a function of time-of-arrival, and that integrate the spatially encoded images into a CUP image.
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16.
公开(公告)号:US20240341603A1
公开(公告)日:2024-10-17
申请号:US18633290
申请日:2024-04-11
Applicant: California Institute of Technology
Inventor: Yang Zhang , Sri Sai Narasimha KS Dhara Venkata , Lihong Wang
CPC classification number: A61B5/0095 , A61B5/4064 , A61B5/6814 , A61B5/6835 , G01N21/1702 , A61B2560/0462 , A61B2562/0233
Abstract: Photoacoustic imaging techniques that deliver diffuse light in transmission mode to the brain and detect acoustic waves transmitted through an acoustic window in the skull.
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公开(公告)号:US12053325B2
公开(公告)日:2024-08-06
申请号:US17248048
申请日:2021-01-06
Applicant: California Institute of Technology
Inventor: Lihong Wang , Shuai Na
CPC classification number: A61B8/15 , A61B8/06 , A61B8/4483 , A61B8/488
Abstract: Among the various aspects described herein is the provision of systems and methods of cross-ray ultrasound tomography. In some embodiments, a cross-ray ultrasound tomography system utilizes an ultrasonic emitter configured to emit one or more ultrasonic waves and an ultrasonic detector array configured to generate one or more radio frequency signals in response to detecting ultrasonic waves. The ultrasonic emitter and the ultrasonic detector array are configured such that the one or more ultrasonic waves are emitted by the ultrasonic emitter at an angle to a focal plane of the ultrasonic detector array.
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公开(公告)号:US20240065555A1
公开(公告)日:2024-02-29
申请号:US18450597
申请日:2023-08-16
Applicant: California Institute of Technology
Inventor: Peng Hu , Lihong Wang
CPC classification number: A61B5/0095 , A61B5/725 , G06T11/008 , G06T2210/41
Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of imaging using photoacoustic computed tomography.
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公开(公告)号:US11672426B2
公开(公告)日:2023-06-13
申请号:US16611939
申请日:2018-05-10
Applicant: California Institute of Technology
Inventor: Lihong Wang , Yang Li , Lei Li
IPC: A61B5/00
CPC classification number: A61B5/0095
Abstract: A photoacoustic imaging system is disclosed that includes an ergodic relay coupled optically to a light source configured to produce a light pulse and further coupled acoustically to a transducer. The ergodic relay is further configured to direct at least two PA signals to the transducer. Each of the at least two PA signals are produced at different positions within the field of view of the object to be imaged in response to illumination by a single light pulse. The transducer detects each of the at least two PA signals after each of at least two delays that correspond to the position at which each PA signal was produced.
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20.
公开(公告)号:US20210321874A1
公开(公告)日:2021-10-21
申请号:US17302041
申请日:2021-04-22
Applicant: California Institute of Technology
Inventor: Lihong Wang , Liming Nie , Xin Cai , Konstantin Maslov , Mark A. Anastasio , Chao Huang , Robert W. Schoonover
Abstract: Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.
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