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公开(公告)号:US20160222203A1
公开(公告)日:2016-08-04
申请号:US14917795
申请日:2014-09-10
Inventor: Susan P. James , Travis S. Bailey , Ketul C. Popat , David A. Prawel , Jackson T. Lewis , Richard L. Koch
CPC classification number: C08L43/04 , A61F2/16 , A61F2002/1681 , A61L27/48 , C08G77/388 , G02B1/043 , G02C7/049
Abstract: Provided herein is a polymeric material comprising a polymer host; and a guest molecule comprising a glycosaminoglycan; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. In some embodiments, the polymer host comprises a silicone-based polymer. In other embodiments, the glycosaminoglycan is chosen from hyaluronic acid and derivatives thereof.
Abstract translation: 本文提供了包含聚合物主体的聚合物材料; 和包含糖胺聚糖的客体分子; 其中所述客体分子设置在所述聚合物主体内,并且其中所述客体分子共价键合至至少一个其它客体分子。 在一些实施方案中,聚合物主体包含硅氧烷基聚合物。 在其它实施方案中,糖胺聚糖选自透明质酸及其衍生物。