公开(公告)号：US09950279B2

公开(公告)日：2018-04-24

申请号：US15654275

申请日：2017-07-19

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Larry J. Cummings

IPC: B08B3/00 ,  B01D15/20 ,  B08B3/08 ,  B01J20/34

CPC classification number: B01D15/203 ,  B01J20/3475 ,  B08B3/08

Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example after a flow-through collection of a target and prior to cleaning the chromatography solid support.

公开(公告)号：US09914749B2

公开(公告)日：2018-03-13

申请号：US14932080

申请日：2015-11-04

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Larry J. Cummings ,  Mark A. Snyder

IPC: C07K1/14 ,  C07K16/00 ,  B01D15/38 ,  B01D15/42 ,  B01J20/04 ,  B01J20/281 ,  B01J20/282

CPC classification number: C07K1/14 ,  B01D15/3847 ,  B01D15/424 ,  B01J20/048 ,  B01J20/281 ,  B01J20/282 ,  C07K16/00

Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.

公开(公告)号：US20170157533A1

公开(公告)日：2017-06-08

申请号：US15432755

申请日：2017-02-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Larry J. Cummings

IPC: B01D15/20 ,  B01J20/34 ,  B08B3/08

CPC classification number: B01D15/203 ,  B01J20/3475 ,  B08B3/08

Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example after a flow-through collection of a target and prior to cleaning the chromatography solid support.

公开(公告)号：US20160052961A1

公开(公告)日：2016-02-25

申请号：US14932080

申请日：2015-11-04

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Larry J. Cummings ,  Mark A. Snyder

IPC: C07K1/14 ,  C07K16/00

CPC classification number: C07K1/14 ,  B01D15/3847 ,  B01D15/424 ,  B01J20/048 ,  B01J20/281 ,  B01J20/282 ,  C07K16/00

Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.