GENE DETECTION SUBSTRATE, GENE DETECTION CHIP AND METHOD FOR PREPARING GENE DETECTION SAMPLE

    公开(公告)号:US20240359174A1

    公开(公告)日:2024-10-31

    申请号:US18029792

    申请日:2022-05-19

    Abstract: A gene detection substrate is provided, including: a substrate; a gene detection channel in the substrate, an opening of the gene detection channel is on one side of the substrate; the gene detection channel includes a sample injection groove, a sample outgoing groove and a flow channel groove sequentially connected and communicated with each other; the flow channel groove includes reaction holes and flow channel structures; the reaction holes are distributed at intervals, and any two adjacent reaction holes are communicated with each other through the flow channel structure; the flow channel structure includes a first, second, and third sub-grooves sequentially connected and communicated with each other; a width of each of the first and third sub-grooves in a first direction is smaller than that of the second sub-groove in the first direction; and the first direction is perpendicular to an arrangement direction of two adjacent reaction holes.

    A QUALITY DETECTION METHOD OF AN IMMUNOCHIP

    公开(公告)号:US20220317116A1

    公开(公告)日:2022-10-06

    申请号:US17600301

    申请日:2021-02-23

    Abstract: A quality detection method of an immunochip is disclosed. At least part of a surface of the immunochip is a modified surface with modifying groups. The method comprises: applying a detection solution containing a labeled antibody on the modified surface of the immunochip, the labeled antibody is an antibody connected with a labeling substance, and the labeled antibody is capable of reacting with the modifying groups and bonding to the modifying groups; removing the labeled antibody that has not reacted with the modifying groups, and detecting the content of residual labeled antibody on the modified surface; and identifying the quality of the immunochip according to the content of residual labeled antibody.

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