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公开(公告)号：US20080082001A1
公开(公告)日：2008-04-03
申请号：US11466925
申请日：2006-08-24
申请人： John D. Hatlestad , Imad Libbus , Aaron Lewicke
发明人： John D. Hatlestad , Imad Libbus , Aaron Lewicke
IPC分类号： A61B5/02
CPC分类号： A61B5/1116 , A61B5/0031 , A61B5/021 , A61B5/02405 , A61B5/076 , A61B5/686 , A61B2562/0219 , A61N1/05
摘要： In an embodiment, an implantable medical device includes a controller circuit, a posture sensing circuit, and a physiological sensing circuit. The controller circuit senses a change in a physiological signal as a result of a change in posture, and generates a response as a function of that change. In another embodiment, the controller circuit identifies a heart failure condition as a function of the change in the physiological signal.
摘要翻译： 在一个实施例中，可植入医疗装置包括控制器电路，姿势感测电路和生理感测电路。 控制器电路作为姿势变化的结果感测生理信号的变化，并产生作为该变化的函数的响应。 在另一个实施例中，控制器电路根据生理信号的变化来识别心力衰竭状况。
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公开(公告)号：US09743859B2
公开(公告)日：2017-08-29
申请号：US12708655
申请日：2010-02-19
申请人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
发明人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
IPC分类号： A61B5/08 , A61B5/11 , A61B5/00 , A61B5/0205
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/1116 , A61B5/7264 , G06F19/00
摘要： A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.
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公开(公告)号：US08417463B2
公开(公告)日：2013-04-09
申请号：US12505926
申请日：2009-07-20
CPC分类号： A61B5/03 , A61B5/021 , A61B5/0537 , A61B5/4878
摘要： This document discusses, among other things, systems and methods for measuring the dynamics of pulmonary congestion in heart failure subjects over time to monitor the subjects susceptibility to pulmonary edema, including sensing and receiving information indicative of a bodily pressure and information indicative of pulmonary fluid, and using the transient responses of these measurements to compute parameters related to the dynamics of thoracic fluid accumulation, such as a critical pressure (Pc), a critical time (Tc), or a filtration index (Kfi).
摘要翻译： 本文件尤其讨论了随着时间的推移，测量心力衰竭受试者的肺充血动力学的系统和方法，以监测受试者对肺水肿的易感性，包括感测和接收指示身体压力的信息和指示肺动脉的信息， 并且使用这些测量的瞬态响应来计算与胸腔积液的动力学相关的参数，例如临界压力（Pc），临界时间（Tc）或过滤指数（Kfi）。
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公开(公告)号：US20120191155A1
公开(公告)日：2012-07-26
申请号：US13437374
申请日：2012-04-02
申请人： John D. Hatlestad , Aaron Lewicke , Keith R. Maile
发明人： John D. Hatlestad , Aaron Lewicke , Keith R. Maile
CPC分类号： G01P21/00 , A61B5/0031 , A61B5/103 , A61B5/1038 , A61B5/1116 , A61B5/686 , A61B2560/0223 , A61B2562/0219 , G01C22/00 , G01C25/00 , G01D18/00 , G01P13/00 , G06F17/40 , G06F19/00
摘要： A system and method automatically calibrate a posture sensor, such as by detecting a walking state or a posture change. For example, a three-axis accelerometer can be used to detect a patient's activity or posture. This information can be used to automatically calibrate subsequent posture or acceleration data.
摘要翻译： 系统和方法通过检测步行状态或姿势变化来自动校准姿势传感器。 例如，可以使用三轴加速度计来检测患者的活动或姿势。 该信息可用于自动校准后续姿势或加速度数据。
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公开(公告)号：US20120172764A1
公开(公告)日：2012-07-05
申请号：US13415281
申请日：2012-03-08
申请人： John D. Hatlestad , Imad Libbus , Aaron Lewicke
发明人： John D. Hatlestad , Imad Libbus , Aaron Lewicke
CPC分类号： A61B5/1116 , A61B5/0031 , A61B5/021 , A61B5/02405 , A61B5/076 , A61B5/686 , A61B2562/0219 , A61N1/05
摘要： In an embodiment, an implantable medical device includes a controller circuit, a posture sensing circuit, and a physiological sensing circuit. The controller circuit senses a change in a physiological signal as a result of a change in posture, and generates a response as a function of that change. In another embodiment, the controller circuit identifies a heart failure condition as a function of the change in the physiological signal.
摘要翻译： 在一个实施例中，可植入医疗装置包括控制器电路，姿势感测电路和生理感测电路。 控制器电路作为姿势变化的结果感测生理信号的变化，并产生作为该变化的函数的响应。 在另一个实施例中，控制器电路根据生理信号的变化来识别心力衰竭状况。
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公开(公告)号：US07704215B2
公开(公告)日：2010-04-27
申请号：US12384271
申请日：2009-04-02
申请人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
发明人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
IPC分类号： A61B5/00
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/1116 , A61B5/7264 , G06F19/00
摘要： A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.
摘要翻译： 一种装置和方法可以根据一天中的时间来监视或趋向于患者的呼吸速率测量。 该装置可以植入或外部收集和分类呼吸速率测量随时间的变化。 关于呼吸率测量的特定类别的趋势化信息然后被传送到远程外部设备，远程外部设备又提供心力衰竭失代偿指示。 呼吸速率测量类别的实例包括每日最大呼吸率值，每日最小呼吸率值，每日最大呼吸率变异值，每日最小呼吸率变异性值和每日中心呼吸率值。 这些呼吸率测量可以进一步分为白天或夜间呼吸率测量。
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公开(公告)号：US20100022911A1
公开(公告)日：2010-01-28
申请号：US12505926
申请日：2009-07-20
IPC分类号： A61B5/00
CPC分类号： A61B5/03 , A61B5/021 , A61B5/0537 , A61B5/4878
摘要： This document discusses, among other things, systems and methods for measuring the dynamics of pulmonary congestion in heart failure subjects over time to monitor the subjects susceptibility to pulmonary edema, including sensing and receiving information indicative of a bodily pressure and information indicative of pulmonary fluid, and using the transient responses of these measurements to compute parameters related to the dynamics of thoracic fluid accumulation, such as a critical pressure (Pc), a critical time (Tc), or a filtration index (Kfi).
摘要翻译： 本文件尤其讨论了随着时间的推移，测量心力衰竭受试者的肺充血动力学的系统和方法，以监测受试者对肺水肿的易感性，包括感测和接收指示身体压力的信息和指示肺动脉的信息， 并且使用这些测量的瞬态响应来计算与胸腔积液的动力学相关的参数，例如临界压力（Pc），临界时间（Tc）或过滤指数（Kfi）。
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公开(公告)号：US07530956B2
公开(公告)日：2009-05-12
申请号：US11820002
申请日：2007-06-15
申请人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
发明人： Aaron Lewicke , Yi Zhang , John D. Hatlestad
IPC分类号： A61B5/00
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/1116 , A61B5/7264 , G06F19/00
摘要： A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.
摘要翻译： 一种装置和方法可以根据一天中的时间来监视或趋向于患者的呼吸速率测量。 该装置可以植入或外部收集和分类呼吸速率测量随时间的变化。 关于呼吸率测量的特定类别的趋势化信息然后被传送到远程外部设备，远程外部设备又提供心力衰竭失代偿指示。 呼吸速率测量类别的实例包括每日最大呼吸率值，每日最小呼吸率值，每日最大呼吸率变异值，每日最小呼吸率变异性值和每日中心呼吸率值。 这些呼吸率测量可以进一步分为白天或夜间呼吸率测量。
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公开(公告)号：US20080262360A1
公开(公告)日：2008-10-23
申请号：US11736058
申请日：2007-04-17
IPC分类号： A61B5/0205
CPC分类号： A61B5/0205 , A61B5/0816 , A61B5/1116 , A61B5/4818 , A61B5/686 , A61N1/3627
摘要： Systems and methods for diagnosing one or more respiration distress manifestations by implantably recognizing their occurrence and evaluating information about the same to provide an indication of present or impending worsening heart failure are discussed. Using information produced by an implantable respiration sensor circuit and an implantable physiological sensor circuit, such as at least one of a physical activity sensor circuit or a posture sensor circuit, an implantable or external processor circuit may detect a respiration disturbance and an associated subsequent arousal from stable state occurrence and thereafter evaluate over time arousal from stable state occurrences to provide the indication of present or impending worsening heart failure. In one example, information about a fluid level within a subject is used in determining the indication of worsening heart failure. In various examples, a regimen is initiated or adjusted in response to the indication of present or impending worsening heart failure.
摘要翻译： 讨论了通过可植入地识别其发生并评估关于其的信息来诊断一种或多种呼吸困扰表现的系统和方法，以提供现在或即将恶化的心力衰竭的指征。 使用由可植入呼吸传感器电路和植入式生理传感器电路产生的信息，例如物理活动传感器电路或姿势传感器电路中的至少一个，可植入或外部处理器电路可以检测呼吸障碍和相关联的随后的唤醒 稳定状态发生，然后评估来自稳定状态发生的随着时间的兴奋，以提供目前或即将恶化的心力衰竭的指征。 在一个示例中，关于受试者内的液位水平的信息用于确定恶化的心力衰竭的指示。 在各种实例中，响应于目前或即将恶化的心力衰竭的指征开始或调整方案。
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公开(公告)号：US09943234B2
公开(公告)日：2018-04-17
申请号：US11736058
申请日：2007-04-17
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/11 , A61B5/00 , A61N1/362
CPC分类号： A61B5/0205 , A61B5/0816 , A61B5/1116 , A61B5/4818 , A61B5/686 , A61N1/3627
摘要： Systems and methods for diagnosing one or more respiration distress manifestations by implantably recognizing their occurrence and evaluating information about the same to provide an indication of present or impending worsening heart failure are discussed. Using information produced by an implantable respiration sensor circuit and an implantable physiological sensor circuit, such as at least one of a physical activity sensor circuit or a posture sensor circuit, an implantable or external processor circuit may detect a respiration disturbance and an associated subsequent arousal from stable state occurrence and thereafter evaluate over time arousal from stable state occurrences to provide the indication of present or impending worsening heart failure. In one example, information about a fluid level within a subject is used in determining the indication of worsening heart failure. In various examples, a regimen is initiated or adjusted in response to the indication of present or impending worsening heart failure.
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