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    Device and method for directional delivery of a drug depot
    11.
    发明授权
    Device and method for directional delivery of a drug depot 有权
    用于定向递送药物库的装置和方法

    公开(公告)号：US08702677B2

    公开(公告)日：2014-04-22

    申请号：US12262823

    申请日：2008-10-31

    Applicant: Thomas A. Simonton ,  Sean M. Haddock ,  John Myers Zanella ,  William F. McKay

    Inventor： Thomas A. Simonton ,  Sean M. Haddock ,  John Myers Zanella ,  William F. McKay

    IPC: A61M31/00 ,  A61M5/00 ,  A61M5/178 ,  A61M25/00

    CPC classification number: A61M25/00 ,  A61B5/04001 ,  A61B5/4893 ,  A61M25/007 ,  A61M25/0084

    Abstract: Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.

    Abstract translation: 提供药物库递送装置和方法用于将一个或多个药物储存器递送到具有或不具有重新定位插管的患者皮肤下方的一个或多个部位。 该装置具有能够插入到患者皮肤下方的部位的插管和用于递送药物库的一个或多个侧口开口。 侧端口与钝头间隔开一段距离，这将允许使用者以距离神经一定距离植入。 该装置还可以包括用于检测套管尖端与神经的接近的电子监视器。 在一些实施方案中，通过检测神经并将药物贮存库输送到神经中或附近来提供递送药物库的方法。

    MULTIPLE COMPONENT MIXING AND DELIVERY SYSTEM
    12.
    发明申请
    MULTIPLE COMPONENT MIXING AND DELIVERY SYSTEM 有权
    多元件混合和输送系统

    公开(公告)号：US20100121310A1

    公开(公告)日：2010-05-13

    申请号：US12268075

    申请日：2008-11-10

    Applicant: Thomas A. SIMONTON ,  Sean M. HADDOCK ,  Lehmann K. LI

    Inventor： Thomas A. SIMONTON ,  Sean M. HADDOCK ,  Lehmann K. LI

    IPC: A61M5/31

    CPC classification number: B01F15/0205 ,  B01F7/00075 ,  B01F11/0082 ,  B01F11/0091 ,  B01F13/002 ,  B01F13/0023 ,  B01F15/0215 ,  B01F15/0223 ,  B01F15/0279 ,  B01F2215/0027 ,  B01F2215/0029

    Abstract: A multiple component cartridge includes a barrel defining a chamber and a longitudinal axis. A first plunger is disposed within the chamber and in sealing engagement with the barrel. The first plunger includes at least one member and is movable relative to the barrel such that the at least one member is configured for movement relative to the first plunger to facilitate passage of at least a first component through the first plunger. A second plunger is disposed within the chamber and in sealing engagement with the barrel. The second plunger includes at least one member and is movable relative to the barrel such that the at least one member of the second plunger is configured for movement relative to the second plunger to facilitate passage of at least a second component through the second plunger.

    Abstract translation: 多部件盒包括限定腔室和纵向轴线的筒体。 第一柱塞设置在室内并与筒密封接合。 所述第一柱塞包括至少一个构件并且可相对于所述筒移动，使得所述至少一个构件被构造成相对于所述第一柱塞运动，以促进至少第一构件通过所述第一柱塞。 第二柱塞设置在腔室内并与枪管密封接合。 所述第二柱塞包括至少一个构件并且可相对于所述筒移动，使得所述第二柱塞的所述至少一个构件被构造成相对于所述第二柱塞移动以便于至少第二构件通过所述第二柱塞。

    Injectable collagen material
    13.
    发明授权
    Injectable collagen material 有权
    注射胶原材料

    公开(公告)号：US08399619B2

    公开(公告)日：2013-03-19

    申请号：US11480067

    申请日：2006-06-30

    Applicant: Hai H. Trieu ,  Jeffrey M. Gross ,  Sean M. Haddock ,  Keith M. Kinnane ,  Thomas A. Simonton

    Inventor： Hai H. Trieu ,  Jeffrey M. Gross ,  Sean M. Haddock ,  Keith M. Kinnane ,  Thomas A. Simonton

    IPC: A61K38/39 ,  A61F2/24 ,  A61F2/30

    CPC classification number: A61K9/0019 ,  A61K9/0024 ,  A61K31/00 ,  A61K31/728 ,  A61L27/24 ,  A61L2400/06 ,  A61L2430/38

    Abstract: A collagen material is disclosed and can include a plurality of particles. Each particle can include an elongated, thin body having one or more arcuate portions and one or more straight portions. Further, each particle can include one or more fibers extending from the body. One or more fibers of one particle can engage the one or more fibers of one or more other particles to establish a matrix of material, where a cross-linking agent may be added in the collagen material. Furthermore, an additive including a radiocontrast medium, a drug, a cellular matter, a biological factor, or a combination thereof may be added to the collagen mixture.

    Abstract translation: 公开了胶原材料，并且可以包括多个颗粒。 每个颗粒可以包括具有一个或多个弓形部分和一个或多个直线部分的细长薄体。 此外，每个颗粒可以包括从身体延伸的一个或多个纤维。 一个颗粒的一个或多个纤维可以与一个或多个其它颗粒的一个或多个纤维接合以建立材料基质，其中交联剂可以添加到胶原材料中。 此外，可以向胶原混合物中添加包括放射性对照培养基，药物，细胞物质，生物因子或其组合的添加剂。

    DEVICE AND METHOD FOR DIRECTIONAL DELIVERY OF A DRUG DEPOT
    14.
    发明申请
    DEVICE AND METHOD FOR DIRECTIONAL DELIVERY OF A DRUG DEPOT 有权
    用于方向递送药物剂量的装置和方法

    公开(公告)号：US20100114075A1

    公开(公告)日：2010-05-06

    申请号：US12262823

    申请日：2008-10-31

    Applicant: Thomas A. SIMONTON ,  Sean M. HADDOCK ,  John Myers ZANELLA ,  William F. MCKAY

    Inventor： Thomas A. SIMONTON ,  Sean M. HADDOCK ,  John Myers ZANELLA ,  William F. MCKAY

    IPC: A61K9/22

    CPC classification number: A61M25/00 ,  A61B5/04001 ,  A61B5/4893 ,  A61M25/007 ,  A61M25/0084

    Abstract: Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.

    Abstract translation: 提供药物库递送装置和方法用于将一个或多个药物储存器递送到具有或不具有重新定位插管的患者皮肤下方的一个或多个部位。 该装置具有能够插入到患者皮肤下方的部位的插管和用于递送药物库的一个或多个侧口开口。 侧端口与钝头间隔开一段距离，这将允许使用者以距离神经一定距离植入。 该装置还可以包括用于检测套管尖端与神经的接近的电子监视器。 在一些实施方案中，通过检测神经并将药物贮存库输送到神经中或附近来提供递送药物库的方法。

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