公开(公告)号：US09289858B2

公开(公告)日：2016-03-22

申请号：US13331472

申请日：2011-12-20

Applicant: Michael Shane Noel ,  Todd C. SeCoy

Inventor： Michael Shane Noel ,  Todd C. SeCoy

IPC: B23K26/00 ,  B23K26/14 ,  B23K26/40 ,  B23K26/38

CPC classification number: B23K26/402 ,  B23K26/388 ,  B23K26/389 ,  B23K2103/42 ,  B23K2103/50

Abstract: A laser machining system is used to precision laser drill holes in an elastomeric material, preferably silicone rubber, to form holes to support miniature electronic components temporarily while they are being processed or tested. The holes are formed by directing laser pulses from a laser to a top surface of the elastomeric material in a plurality of passes in a direction proceeding from a non-zero inner diameter to the desired diameter or from the desired diameter to the inner diameter. The plurality of passes forms a first pattern such that a successive pass of the plurality of passes overlaps a previous pass of the plurality of passes. The first pattern is repeated without changing direction or the first pattern is repeated while reversing the direction until the hole is formed through a bottom surface of the elastomeric material.

Abstract translation: 激光加工系统用于将弹性体材料（优选硅橡胶）中的激光钻孔精确地形成孔，以在处理或测试时临时支撑微型电子部件。 通过在从非零内径到期望直径或从所需直径到内径的方向上以多次通过将激光脉冲从激光引导到弹性体材料的顶表面而形成孔。 多个通道形成第一图案，使得多个通道的连续通过与多个通过的先前通过重叠。 在不改变方向的情况下重复第一图案，或者在反转方向的同时重复第一图案，直到穿过弹性体材料的底表面形成孔。

公开(公告)号：US09068013B2

公开(公告)日：2015-06-30

申请号：US13811981

申请日：2011-07-22

Applicant: Thomas M. Lancaster ,  Robert Butters ,  Naomi Choodnovskiy ,  Todd C. Zion

Inventor： Thomas M. Lancaster ,  Robert Butters ,  Naomi Choodnovskiy ,  Todd C. Zion

IPC: C07K14/42

CPC classification number: C07K14/42

Abstract: In one aspect, the disclosure provides cross-linked materials that include multivalent lectins with at least two binding sites for glucose, wherein the lectins include at least one affinity ligand which is capable of competing with glucose for binding with at least one of said binding sites and is covalently linked to a cysteine residue of the lectins; and conjugates that include two or more separate affinity ligands bound to a conjugate framework, wherein the two or more affinity ligands compete with glucose for binding with the lectins at said binding sites and wherein conjugates are cross-linked within the material as a result of non-covalent interactions between lectins and affinity ligands on different conjugates. These materials are designed to release amounts of conjugate in response to desired concentrations of glucose. Depending on the end application, in various embodiments, the conjugates may also include a drug and/or a detectable label.

Abstract translation: 一方面，本公开提供了交联材料，其包括具有至少两个葡萄糖结合位点的多价凝集素，其中所述凝集素包括至少一种亲和配体，其能够与葡萄糖竞争与至少一个所述结合位点 并与凝集素的半胱氨酸残基共价连接; 以及包含与缀合物框架结合的两个或更多个分离的亲和配体的缀合物，其中所述两个或更多个亲和配体与葡萄糖竞争与所述结合位点处的凝集素结合，并且其中缀合物在材料内交联， 在不同共轭物上的凝集素和亲和配体之间的共价相互作用。 这些材料被设计为响应于期望的葡萄糖浓度释放结合物的量。 根据最终应用，在各种实施方案中，缀合物还可以包括药物和/或可检测标记。

公开(公告)号：US20150004563A1

公开(公告)日：2015-01-01

申请号：US14485351

申请日：2014-09-12

Applicant: Mark H. Blaisdell ,  Todd C. Liston

Inventor： Mark H. Blaisdell ,  Todd C. Liston

IPC: A61C8/00 ,  A61C13/08 ,  A61C9/00

CPC classification number: A61C8/008 ,  A61C8/0001 ,  A61C13/34

Abstract: Anatomical healing abutments, kits and methods for promoting healing of gingival tissue around a subgingival void of a given tooth position. The abutment includes a cuff body having an anatomical subgingival portion extending from an implant end to the gingival margin of the patient, and an emergent crown portion extending occlusally from the subgingival portion beyond the gingival margin. A directional alignment body may be disposed on the cuff body and configured to extend bucally beyond an outer perimeter of the cuff body when the cuff body is anatomically aligned relative to the void. The subgingival portion has an asymmetric cross-section and is occlusally flared to anatomically fill the void and support gingival tissue around the void to minimize slump of tissue into the void. The crown portion has a mesial-distal width that spans a width of the gingival margin and an occlusal height to extend beyond the gingival margin.

Abstract translation: 解剖学治疗基台，成套工具和方法，用于促进齿龈组织周围龈下空隙牙齿位置愈合。 基台包括具有从植入物端延伸到患者牙龈边缘的解剖性龈下部分的袖带体，以及从龈下部分咬合地延伸超过牙龈边缘的出血冠部。 定向对准体可以设置在袖带体上并且构造成当袖带体相对于空隙在解剖学上对准时，蜂窝状体可以延伸超过袖带体的外周。 龈下部分具有不对称的横截面并且被咬合地张开以解剖学地填充空隙并支撑空隙周围的牙龈组织以最小化组织进入空隙的坍落度。 冠部具有跨越牙龈边缘宽度的内侧 - 远侧宽度，并且咬合高度延伸超过牙龈边缘。

公开(公告)号：US08906850B2

公开(公告)日：2014-12-09

申请号：US13145525

申请日：2010-01-27

Applicant: Todd C. Zion ,  Thomas M. Lancaster

Inventor： Todd C. Zion ,  Thomas M. Lancaster

IPC: A61K38/28 ,  C07K14/62

CPC classification number: C07K14/62 ,  A61K38/28 ,  A61K47/549

Abstract: The present disclosure provides crystalline insulin-conjugates. The present disclosure also provides formulations, methods of treatment, methods of administering, and methods of making that encompass these crystalline insulin-conjugates.

Abstract translation: 本公开提供结晶胰岛素缀合物。 本公开还提供了制剂，治疗方法，施用方法以及制备其包括这些结晶性胰岛素缀合物的方法。

公开(公告)号：US20140196335A1

公开(公告)日：2014-07-17

申请号：US14213478

申请日：2014-03-14

Applicant: Patrick J. Barkdoll ,  Stanley C. Valiulis ,  Nicholas C. Juric ,  Todd C. Westberg

Inventor： Patrick J. Barkdoll ,  Stanley C. Valiulis ,  Nicholas C. Juric ,  Todd C. Westberg

IPC: G09F3/20

CPC classification number: G09F3/204 ,  Y10T29/49826

Abstract: A label holder for a retail display apparatus is provided. The label holder comprises a front panel, a sign clip, and a mounting structure for securing the label holder to the retail display apparatus. The sign clip includes a leg portion, including a gripping surface, and resiliently biases to secure a sign between the gripping surface and the front panel. In one embodiment, defined in the front panel are two sign engagement projections that interleavingly interact with the gripping surface. The sign clip is integrally connected to the front panel via an integral hinge and pivots relative to the front panel through the integral hinge between a normal state and a biased state. In the normal state, the leg portion of the clip is positioned proximate the front panel. In the biased state, the leg portion is spaced apart from the front panel and holds a secondary sign therebetween.

Abstract translation: 提供了用于零售显示装置的标签支架。 标签保持器包括前面板，标志夹和用于将标签保持器固定到零售显示装置的安装结构。 标志夹包括包括抓握表面的腿部部分，并且弹性地偏压以在握持表面和前面板之间固定标志。 在一个实施例中，在前面板中限定的是与抓握表面交织地相互作用的两个符号接合突起。 标志夹通过一体式铰链与前面板一体连接，并且在正常状态和偏置状态之间通过整体铰链相对于前面板枢转。 在正常状态下，夹子的腿部位于靠近前面板的位置。 在偏置状态下，腿部与前面板间隔开，并在其间保持次要标志。

公开(公告)号：US08776461B2

公开(公告)日：2014-07-15

申请号：US13166374

申请日：2011-06-22

Applicant: Todd C. Carlson ,  Timothy J. Rogge

Inventor： Todd C. Carlson ,  Timothy J. Rogge

IPC: E06B1/04 ,  E06B3/00 ,  E06B3/988 ,  E04D1/36 ,  E04C2/38

CPC classification number: E06B1/36 ,  E06B1/56 ,  E06B3/20 ,  E06B3/4618 ,  E06B7/14 ,  E06B2001/628

Abstract: A plastic window frame trim is for installation of a window in a corrugated metal building wall having a cut opening with a top edge, bottom edge, and side edges, each of the edges being backed by framing members. The window frame trim includes: a frame header J-channel with a flange; a frame footer J-channel with a flange; a pair of nailing fins; and fasteners. The trim header J-channel, footer J-channel, and nailing fins are attached to the window frame. The window frame is lifted so frame header J-channel flange slides between the top edge of the metal building wall and a framing member at the top of the cut opening. The window is lowered so footer J-channel flange slides between the bottom edge of the metal building wall and a framing member at the bottom of the cut opening so that window frame rest on the window sill. Fasteners attach the window frame to the framing members through the metal building wall. Trim caps snap over the nailing fins to finish the trimmed window.

Abstract translation: 塑料窗框装饰件用于在具有顶部边缘，底部边缘和侧边缘的切割开口的波纹金属建筑物墙壁中安装窗户，每个边缘由框架构件支撑。 窗框修剪包括：具有法兰的框架头J通道; 带法兰的框架脚板J通道; 一对钉子鳍; 和紧固件。 修剪头J通道，页脚J通道和钉子叶片连接到窗框。 窗框被提起，因此框架接头J通道法兰在金属建筑物墙壁的顶部边缘和切割开口顶部的框架构件之间滑动。 窗户下降，所以脚踏板J形通道法兰在金属建筑墙壁的底部边缘和切割开口底部的框架构件之间滑动，以便窗框搁置在窗台上。 紧固件通过金属建筑墙将窗框连接到框架构件。 修剪帽卡在钉子上以完成修剪的窗口。

公开(公告)号：US08769225B2

公开(公告)日：2014-07-01

申请号：US13458872

申请日：2012-04-27

Applicant: Dale H. Anderson ,  Philip M. Doatmas ,  Michael R. Groseclose, Jr. ,  Paul A. Jennas, II ,  Larry Juarez ,  Brian S. McCain ,  David Montgomery ,  Jason L. Peipelman ,  Joshua M. Rhoades ,  Todd C. Sorenson ,  David V. Valverde

Inventor： Dale H. Anderson ,  Philip M. Doatmas ,  Michael R. Groseclose, Jr. ,  Paul A. Jennas, II ,  Larry Juarez ,  Brian S. McCain ,  David Montgomery ,  Jason L. Peipelman ,  Joshua M. Rhoades ,  Todd C. Sorenson ,  David V. Valverde

IPC: G06F13/00 ,  G06F13/28

CPC classification number: G06F3/0647 ,  G06F3/0613 ,  G06F3/0685

Abstract: In one embodiment, pursuant to migrating the data from the first to the second storage medium, the data is allocated to the second storage medium while retaining an allocation of the data in the first storage medium. If the data is migrated from the second storage medium back to the first storage medium, the data is pointed to the allocation of the data in the first storage medium to alleviate data movement from the second storage medium to the first storage medium. If the allocation of the data in the first storage medium is determined to be needed for other data, the allocation of the data in the first storage medium is freed.

公开(公告)号：US08694165B2

公开(公告)日：2014-04-08

申请号：US12826225

申请日：2010-06-29

Applicant: Laura L. Smith ,  Tyrone T. Thorsen ,  Todd C. Tatum ,  Alan D. Gatzke

Inventor： Laura L. Smith ,  Tyrone T. Thorsen ,  Todd C. Tatum ,  Alan D. Gatzke

IPC: G05B13/00

CPC classification number: G06F3/04847 ,  G05B2219/25011

Abstract: An example method is provided and includes establishing a communication pathway to a building element configured to control at least one environmental setting within a room. The method also includes communicating an ability to control the environmental setting within the room to an endpoint configured to participate in a meeting session. The method further includes receiving a command from the endpoint to adjust the environmental setting during the meeting session. The command can be communicated to the building element. In more specific examples, the method can include registering with one or more application program interfaces (APIs) associated with the building element, and communicating a credential to the building element in order to provide an authentication for controlling the environmental setting. In yet other embodiments, the command to adjust the environmental setting is received via a menu of a user interface provided by a video conferencing platform.

Abstract translation: 提供了一种示例性方法，并且包括建立到建筑构件的通信路径，该建筑构件被配置为控制房间内的至少一个环境设置。 该方法还包括传达将房间内的环境设置控制到被配置为参与会议会话的端点的能力。 该方法还包括从会议会话期间接收来自端点的命令以调整环境设置。 该命令可以传达给建筑元件。 在更具体的示例中，该方法可以包括与与构建元件相关联的一个或多个应用程序接口（API）注册，以及将凭证传送给建筑元件，以便提供用于控制环境设置的认证。 在其他实施例中，通过由视频会议平台提供的用户界面的菜单来接收调整环境设置的命令。

公开(公告)号：US08628327B1

公开(公告)日：2014-01-14

申请号：US13633387

申请日：2012-10-02

Applicant: Mark H. Blaisdell ,  Todd C. Liston

Inventor： Mark H. Blaisdell ,  Todd C. Liston

IPC: A61C11/00

CPC classification number: A61C13/34 ,  A61C8/0001 ,  A61C8/008

Abstract: Casting jigs, methods, and kits that may be used in manufacture of anatomical healing caps. A casting jig may include a body having one or more wells within the body, each well being open at a proximal end thereof and having a negative shape corresponding to an anatomical healing cuff body of a given tooth position. Each respective anatomical healing cuff body negative shape includes an asymmetrical cross-section and an irregular surface so that an anatomical healing cuff body having said shape is configured to provide substantially custom filling of at least an emergence portion of a void where a natural tooth once emerged or should have emerged from the void (e.g., in the case of a congenitally missing tooth). The casting jig may further include a socket at a distal end of each well that is configured to releasably receive therein a dental implant or dental implant analog.

Abstract translation: 可用于制造解剖愈合帽的铸造夹具，方法和试剂盒。 铸造夹具可以包括在主体内具有一个或多个孔的主体，每个孔在其近端处是开放的，并且具有对应于给定牙齿位置的解剖学愈合箍体的负形状。 每个相应的解剖修复袖带体负形状包括不对称的横截面和不规则表面，使得具有所述形状的解剖学治疗封套体构造成提供至少一个出现天然牙齿的空隙的出现部分的基本上定制的填充 或者应该从空洞出现（例如，在先天缺失的牙齿的情况下）。 铸造夹具还可以包括在每个孔的远端处的插座，其构造成可释放地容纳牙齿植入物或牙科植入物模拟物。

公开(公告)号：US20140008539A1

公开(公告)日：2014-01-09

申请号：US13931348

申请日：2013-06-28

Applicant: John Magie COFFIN ,  Damian W. ASHMEAD ,  Todd C. STROTHER

Inventor： John Magie COFFIN ,  Damian W. ASHMEAD ,  Todd C. STROTHER

IPC: G01N21/25

CPC classification number: G01N21/0303 ,  G01J3/0202 ,  G01N21/255 ,  G01N21/35 ,  G01N2021/3595 ,  G01N2201/066

Abstract: The present invention is thus directed to an automated system and method of varying the optical path length in a sample that a light from a spectrophotometer must travel through. Such arrangements allow a user to easily vary the optical path length while also providing the user with an easy way to clean and prepare a transmission cell for optical interrogation. Such path length control can be automatically controlled by a programmable control system to quickly collect and stores data from different path lengths as needed for different spectrographic analysis. Such a methodology and system, as presented herein, is able to return best-match spectra with far fewer computational steps and greater speed than if all possible combinations of reference spectra are considered.

Abstract translation: 因此，本发明涉及一种自动化系统和方法，其改变来自分光光度计的光必须穿过的样品中的光程长度。 这样的布置允许用户容易地改变光路长度，同时还为用户提供了清洁和准备用于光询问的传输单元的简单方法。 这种路径长度控制可以由可编程控制系统自动控制，以便根据不同光谱分析的需要快速收集和存储来自不同路径长度的数据。 如本文所述，这种方法和系统能够以比考虑参考光谱的所有可能组合的方式更少的计算步骤和更大的速度返回最佳匹配光谱。