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    Donated blood collection kit
    12.
    发明授权
    Donated blood collection kit 有权
    献血采集套件

    公开(公告)号：US09539374B2

    公开(公告)日：2017-01-10

    申请号：US12778710

    申请日：2010-05-12

    申请人： Lise N. Halpern ,  Tim Costello ,  Jonathan White

    发明人： Lise N. Halpern ,  Tim Costello ,  Jonathan White

    IPC分类号： C12M1/00 ,  B65B5/00 ,  A61M1/02 ,  B01L3/00 ,  B01L9/00

    CPC分类号： A61M1/02 ,  A61M2205/6054 ,  A61M2205/6063 ,  A61M2205/6072 ,  A61M2209/06 ,  B01L3/5453 ,  B01L9/54

    摘要： A donated blood collection kit includes an easy-to-open closed container. Stored within the container are items necessary or useful for collecting donated blood, such as an antiseptic scrub, an antiseptic swab, test tubes, a blood collection container, a gauze pad and a sheet of pre-printed adhesive barcode labels. Each kit is assigned a unique identification when the kit is manufactured. The identification may eventually be used as the unique donor identification for a unit of donated blood that is collected using the items in the kit. The container is pre-labeled with the unique identification, such as by a barcode or an RF-ID tag. The test tubes and, if included, the blood collection container are pre-labeled with the same unique donor identification. The adhesive barcode labels in the container are pre-printed with the same unique donor identification and may be affixed to items that are not provided in the kit but, nonetheless, should be associated with the unit of blood that may be collected using the kit. Information about lot numbers and expiration dates for the items in the kit may be encoded in the kit's unique identification and/or stored in a database in association with the kit's identification.

    摘要翻译： 捐赠的血液收集套件包括一个易于打开的密闭容器。 储存在容器内的是用于收集捐赠血液的必需或有用的物品，例如消毒洗涤剂，防腐拭剂，试管，采血容器，纱布垫和预先印刷的粘合剂条形码标签片。 当套件被制造时，每个套件被分配一个唯一的标识。 该鉴定可能最终被用作使用试剂盒中的物品收集的捐赠血液单位的唯一捐赠者身份。 容器被预先标记有唯一标识，例如通过条形码或RF-ID标签。 试管和（如果包括的话）采血容器用相同的独特供体标识物进行预标记。 容器中的粘合剂条形码标签被预先印有相同的独特的供体标识，并且可以粘贴在试剂盒中未提供的物品上，但仍应与使用试剂盒收集的血液单位相关。 关于套件中项目的批号和有效期的信息可以编码成套件的唯一标识和/或与套件标识相关联的数据库中。

    Radioprotector compounds and methods
    13.
    发明授权
    Radioprotector compounds and methods 有权

    公开(公告)号：US08999993B2

    公开(公告)日：2015-04-07

    申请号：US13640188

    申请日：2011-04-06

    申请人： Roger Francis Martin ,  Jonathan White ,  Pavel Lobachevsky ,  David Winkler ,  Colin Skene ,  Sebastian Marcuccio

    发明人： Roger Francis Martin ,  Jonathan White ,  Pavel Lobachevsky ,  David Winkler ,  Colin Skene ,  Sebastian Marcuccio

    IPC分类号： A61K31/496 ,  C07D235/20 ,  C07D401/14 ,  C07D235/18 ,  C07D403/14 ,  C07D405/14 ,  C07D413/04 ,  C07D413/14

    CPC分类号： C07D401/14 ,  C07D235/18 ,  C07D403/14 ,  C07D405/14 ,  C07D413/04 ,  C07D413/14

    摘要： The invention relates to novel compounds, processes for their preparation and their use in protecting biological materials from radiation damage (radioprotection). Preferred compounds of the invention are those of Formula II, as follows: wherein W represents —N(R1R2) where R1 and R2 are not both hydrogen and where they may together form a 5, 6 or 7 membered ring structure, —NHN(R1R2), —NHR3N(R1R2), —NHR3OR2, —N(R3)R3OR2, —N(R1)R3OR3OR3, —OR3NR1R2, —OR3 or W represents piperidyl, piperazinyl, morpholinyl, thiomorpholinyl or diazepanyl each of which may be optionally substituted by C1 to C4 alkyl, C2 to C4 alkenyl, —N(CO)N(R1R2), —N(CO)OR1, —N(CO)OR3OH, —(CO)NR1R2, —R3(CO)NR1R2, —R3OR1, —OR1, —N(R1R2) or —NH—; R1 and R2 are the same or different and are selected from hydrogen, C1 to C4 alkyl or C2 to C4 alkenyl; R3 is a C1 to C4 alkyl or C2 to C4 alkenyl group or chain; Z is the same or different and represents N or CH; Z′ is the same or different and represents N or C; X represents CH, N or NH, where is a double bond when X is CH or N and a single bond when X is NH; X′ represents N or NH, wherein when X is CH or NX′ is NH and wherein X and X′ are different and further where is a double bond when X′ is N and a single bond when X′ is NH; Q represents H, alkoxyl, —NR1R2, F or Cl; Q1 is absent when Z′ is N and when Z′ is C it represents H, alkoxyl, —NR1R2, F or Cl; A represents a five to ten membered single or multiple ring structure with heterocyclic N or O located at the ortho position, said ring including optional double bonds, substitutions and/or other heteroatoms and pharmaceutically acceptable derivatives thereof.