公开(公告)号：US5869451A

公开(公告)日：1999-02-09

申请号：US764640

申请日：1996-12-11

申请人： William J. Dower ,  Ronald W. Barrett ,  Steven E. Cwirla ,  Christian M. Gates ,  Peter J. Schatz ,  Palaniappan Balasubramanian ,  Christopher R. Wagstrom ,  Richard Wayne Hendren ,  Randoph B. DePrince ,  Surekha Podduturi ,  Qun Yin

发明人： William J. Dower ,  Ronald W. Barrett ,  Steven E. Cwirla ,  Christian M. Gates ,  Peter J. Schatz ,  Palaniappan Balasubramanian ,  Christopher R. Wagstrom ,  Richard Wayne Hendren ,  Randoph B. DePrince ,  Surekha Podduturi ,  Qun Yin

IPC分类号： A61K38/00 ,  A61K38/02 ,  A61P7/00 ,  A61P43/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/52 ,  C07K17/08

CPC分类号： C07K14/524 ,  A61K38/00

摘要： Described are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.